DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31064 and fab1

DIOPT Version :9

Sequence 1:	NP_001287560.1	Gene:	CG31064 / 43277	FlyBaseID:	FBgn0051064	Length:	877	Species:	Drosophila melanogaster
Sequence 2:	NP_611269.1	Gene:	fab1 / 37033	FlyBaseID:	FBgn0028741	Length:	1809	Species:	Drosophila melanogaster

Alignment Length:	287	Identity:	59/287 - (20%)
Similarity:	106/287 - (36%)	Gaps:	79/287 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   601 KLLE--KDIHEKQDTIVSLRRQLDDIKQINLEMYRKLQD-----CKASLTHKTELMTKLEVQKED 658
            ||.|  ::..:|.:::..  |.::.|:.:..:.|..:.|     ..:|.|...:::.|.:...:.
  Fly    20 KLTEFARNFEDKPESLFG--RVVNKIQNVYNQSYNTVNDISSGSSSSSSTQPVQVVGKSQFFSDS 82

  Fly   659 MASTIDQLEKKWSHDKSNLGE-----ILKTTSQTLTTQVTASEERAARAEAESRIEREWRISLQE 718
            ..||.:..:.:.|...|...:     .::|.|:|..|. |:|...|..:|...|:|   .:.|..
  Fly    83 QTSTAEIADVETSSQSSVRPQPPTTLSIRTNSETRGTS-TSSNTAAEDSETSDRVE---TLPLPT 143

  Fly   719 KELKLKEKIANLQGCLKELSEEKERNGKLKADLDKVRTQWSEAQTTLEELGIQLSVSKLKVSEMQ 783
            .|......::|:...:..:...|..|                            .:...|.:|:|
  Fly   144 SEANQGRTVSNVLKHISNIVATKNNN----------------------------DLRNYKDTELQ 180

  Fly   784 DQERRQRQLLSGSAQSLQAMPEAVGSPGIWAPDSIATHCTACEREFNLTRRKHHCRSCGEIFCKA 848
                                       ..|.|||.|..|..|.::|:..|||||||.||:|||..
  Fly   181 ---------------------------RFWMPDSKAKECYDCSQKFSTFRRKHHCRLCGQIFCSK 218

  Fly   849 CSEHTLP--LLNAQGQPGKPVRVCDNC 873
            |....:|  ::...|.    ::||:.|
  Fly   219 CCNQVVPGMIIRCDGD----LKVCNYC 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31064	NP_001287560.1	RUN	316..439	CDD:280855
		CASP_C	495..>634	CDD:285395	7/34 (21%)
		FYVE_RUFY1_like	813..874	CDD:277261	26/63 (41%)
fab1	NP_611269.1	FYVE_PIKfyve_Fab1	182..243	CDD:277264	26/64 (41%)
		DEP	329..397	CDD:214489
		Fab1_TCP	464..717	CDD:239450
		PIPKc	1413..1797	CDD:295374
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2108
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.030