Protein Alignment CG31064 and CG3632

DIOPT Version :10

• Sequence 1: NP_001287560.1
• Gene: CG31064 / 43277
• FlyBaseID: FBgn0051064
• Length: 877
• Species: Drosophila melanogaster
• Sequence 2: NP_001096996.1
• Gene: CG3632 / 32589
• FlyBaseID: FBgn0030735
• Length: 1250
• Species: Drosophila melanogaster
• Alignment Length: 1155
• Identity: 228/1155 - (19%)
• Similarity: 365/1155 - (31%)
• Gaps: 425/1155 - (36%)

  Fly    58 SGSATSLSSGT-MAAKKAPQTGQQQVGKSAKSATAATPTGTTAT-AIGATATTRAQAAAAKSQKG 120
            ||..::.::|. :.||....|....:.|...:.||:.|....|: .|.|..:.|.|.:.......
  Fly   158 SGIVSAQANGNGLIAKDRCLTLHNGLAKPTANVTASNPLPDPASETISAAMSNRLQRSVRYESDF 222

  Fly   121 QNPPSQ--------------QVQPKQQPPQPQQTQQQPLVLQQQQASNSSN---TIALPKA--SH 166
            :|..::              ....|..|..|.:. ..|..:..:...|.:|   :..||..  .|
  Fly   223 KNEVARLGFDLKGSWRISTANADFKLCPSYPPKL-LVPCCITDEMLHNVANFRGSRRLPAVVWRH 286

  Fly   167 ANTSEELAGGVQDTIYLCNFRVSVDGEWLCLKELQDIDVAGGTGNQA-----AQTSEKLAGGSSS 226
            ..:...||...|..:....:|.:.|.:  .||.|.|. .|...|..|     |....:...||..
  Fly   287 QKSGAILARCSQPEVGWLGWRNTRDEQ--LLKALADA-CAFDRGEHARHSTCANAKAQPTKGSKE 348

  Fly   227 QTGGFG----SNYNVGSSSSKR------------NSKRFSGLSTGSGSGGNAGGGGGLDITDNAR 275
            ..|..|    |:.::..||.:.            :::.::...|      |...|||.:..: ..
  Fly   349 TNGQSGLSGKSSPSLDDSSHEELTLDEIKKILIVDARSYTSAVT------NRARGGGCECIE-YY 406

  Fly   276 DTAEIERSNLVNICKL-----VVKEL-------------LEQSL--------------------R 302
            ..||||..||.||..:     .|::|             ||:::                    :
  Fly   407 PCAEIEFMNLGNIHAIRKSFHAVRQLCASSPDDPNWYGQLEKTMWMQHLSGLLGATMTVVHTIEK 471

  Fly   303 YGR----------------------MLDSDHLPLQHFFIVIEHV---LGHGLRPKKGLLGPRKE- 341
            .||                      .||..:..::.|.:::|..   .||....:.| .||..:
  Fly   472 NGRPVLVHCSDGWDRTPQIVATAQLCLDPYYRTVEGFRVLVEREWLNFGHKFADRSG-NGPNSDE 535

  Fly   342 ---------LW-DLLQSVEHYCPEAQDITASVRDLPTVRTHIGRARAWLRIALMQKKLS----DY 392
                     .| ||:..:....|.:.:.:.|                 ..|.|.|..||    .:
  Fly   536 VNERCPVFLQWLDLVHQIHRQYPCSFEFSIS-----------------YLIKLAQHSLSCLFGTF 583

  Fly   393 L-QALIEHREDSLFD-------------YYEPHALMMSDEIV--------------VIMGILVGL 429
            | .:|.|..|:|:||             |..|.....:::::              |.:|.|...
  Fly   584 LCNSLRERIENSVFDRTFSVWPFLAETMYRNPLYKHETEKVLWPAHSVRFLYFWSDVYLGSLGNK 648

  Fly   430 NVIDCNLCVKE---------------EDLDSQ---QGVIDFSLYLRSSSRNADAAPEDSAPPALL 476
            |..|..|...|               |||.:.   |..|        |.|::|  |..:....:.
  Fly   649 NGTDLPLLSNERQSGHNGLMAKTRSSEDLTTNELGQSTI--------SRRSSD--PNLTVESIVT 703

  Fly   477 DA--TGQGNMIAVLDQKNYIEELNRHLNATVGNLQAKVE-----SLTTTNA-------------- 520
            |.  ....:|..:..:.|         |:...|:|..|:     .|..|:|
  Fly   704 DCFNANSNSMFDIRSEAN---------NSVSENVQESVKDSKEVELDVTDATEVGPCGRSNNPIP 759

  Fly   521 --------LMKEDLAIARNSLLALQAENQAMRQSTSAGDNNSTGS---GGSSDKDK----EKASE 570
                    ..|.|:         |:.|:|..|:|:........||   .|||:.||    .::.|
  Fly   760 DFHNDQSTASKRDI---------LEVESQTQRRSSLESSQLIPGSVFIFGSSENDKNAVPSESEE 815

  Fly   571 ELVEERRKNSELEKEL---------KLQVSLKAE--SDMAMKLLEKDIHEKQDTIVSLRRQLDDI 624
            .|...::.|||..:..         :..|.||:|  ||::..|....|....||:
  Fly   816 SLATSQKLNSESGRPFFIFGSSENDQSPVPLKSEDTSDISRALWHGAIETSTDTL---------- 870

  Fly   625 KQINLEMYRKLQDCKASLTHKTELMTKLEVQKEDMASTIDQLEKKWSHDKSNLGEILKTTSQTLT 689
              |..|..:|.....:|..|.|....:|......:.||......|.|...:||.::....:..:.
  Fly   871 --IPAEPVQKPNSDNSSRDHITSPTMELVSGDRKLESTSTVQASKISQSYNNLPKVHIRPNAVIC 933

  Fly   690 TQVTASEERAARAEA-----ESRIEREWRISLQEKELKLKEKIANLQGCLKELSEEKERNGKLKA 749
            .|         |.:|     :.::.||   :....:....||:|      |:.:.....||.|.|
  Fly   934 PQ---------RVDAFPHHLDLQVPRE---TTGNPDRCKPEKLA------KDANANANANGSLLA 980

  Fly   750 --------------DLD---------------KVR------------------------------ 755
                          ||.               ::|
  Fly   981 SDGYNGEESLFISPDLQRFVGQSPFDAPSTGGRIRRNTFGSSYSRDMKFTAENGSAHQFPSSGII 1045

  Fly   756 ----TQWSE-AQTTL---EELGIQLSVSKLKVSE-MQDQERRQRQLL------------------ 793
                |.:.| ||.|:   :.|...||...:::.: :|:.:.|:..||
  Fly  1046 SLPPTPFQERAQFTISCPDGLAHGLSEQNIRLHQIVQEHKLREEMLLREIHGMRLALLEKGCPSC 1110

  Fly   794 ------------------SGSAQSLQAMPEAVG--------------SPGIWAPDSIATHCTACE 826
                              :.|..|.:|:.|..|              |..:|.||...:.|::|:
  Fly  1111 NSIVSTNMEHENGSDIVENASTCSWEAVEERSGPASYAPSSIQEKKASSVLWVPDHAVSRCSSCQ 1175

  Fly   827 REFNLTRRKHHCRSCGEIFCKACSEHTLPLLNAQGQPGKPVRVCDNCYAA 876
            .||.|.||||||||||||||..|||...||.|.  :...|||:|.:||.:
  Fly  1176 TEFWLGRRKHHCRSCGEIFCADCSEFWAPLPNE--KLFNPVRLCGSCYTS 1223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31064	NP_001287560.1	RUN_RUFY1_like	281..436	CDD:439043	44/260 (17%)
		Smc	<562..>807	CDD:440809	62/368 (17%)
		FYVE_RUFY1_like	813..874	CDD:277261	32/60 (53%)
CG3632	NP_001096996.1	PH-like	35..147	CDD:473070
		Myotub-related	221..591	CDD:461958	70/398 (18%)
		FYVE_MTMR4	1162..1221	CDD:277272	32/60 (53%)