Protein Alignment CG31064 and Rubicon

DIOPT Version :10

• Sequence 1: NP_001287560.1
• Gene: CG31064 / 43277
• FlyBaseID: FBgn0051064
• Length: 877
• Species: Drosophila melanogaster
• Sequence 2: NP_572496.1
• Gene: Rubicon / 31803
• FlyBaseID: FBgn0030055
• Length: 827
• Species: Drosophila melanogaster
• Alignment Length: 694
• Identity: 131/694 - (18%)
• Similarity: 228/694 - (32%)
• Gaps: 224/694 - (32%)

  Fly   302 RYGRMLDSDHLPLQHFFIVIEHVLGHGLRPKKGLLGP--RKELWD----LLQSV---------EH 351
            |..:..|...|..|....:::|          |||.|  .:.|.|    ||.|.         :.
  Fly    63 RAAKSTDGLQLLAQSCTRILQH----------GLLQPVELRRLADDFEFLLASAGKQQQQTKPQP 117

  Fly   352 YCPE--AQDITASVRDLPTVRTHIGRARAWLRIALMQKKLSDYLQALIEHREDSLFDYYEPHALM 414
            |.|:  |:|..:.|..   |...:|.   |....|..:.||..||.|:...|  |.:.|.|
  Fly   118 YRPDYAARDSASMVNG---VEEFLGE---WTTRCLRARCLSQCLQTLVSDPE--LMELYYP---- 170

  Fly   415 MSDEIVV-----IMGILVGLNVIDCNLCVKEEDLDSQQGVIDFSLYLRSSSR-NADAAPEDSAPP 473
             |:|..:     ...:.|.|..:..|    :..|.||..|.....:.|:.|: |...:|:..|.|
  Fly   171 -SEEAFLRRSGDATALFVCLTAVQLN----QSGLLSQLEVRHQVRHRRTCSQPNFSISPKLQAVP 230

  Fly   474 ALLDATGQGNMIAVLDQKNYIEELNRHLNATVGNLQAKVESLTTTNALMKEDLAIARNSLLALQA 538
            .           ..|.::.::..|.     ::.||..:.|.|       .:..|..|.......:
  Fly   231 E-----------ERLQKRIFLRRLK-----SLPNLSQEDEEL-------DDRAAFRRRCQTFSSS 272

  Fly   539 ENQAMRQSTSAGDNNSTGSGGSSDKDK--------------EKASEELVEERRKNSELEKELKLQ 589
            .:..:|:...  |..||.|..|.|..:              ::..:|:.||..:        |||
  Fly   273 RSHKLREDHL--DAPSTSSCSSHDSPRRIQLINCDDIKIWTDQTPQEVPEEVHE--------KLQ 327

  Fly   590 VSLKAESDMAMKL-----------------LEKDIHEKQDTIVSLRRQLDDIKQINLEMYRKLQD 637
            .:.||.:.:...|                 :..|::...|     ...||....:|   .|||:
  Fly   328 QASKASTSVGGYLGSFFGSPPLYTSWFHRGVGDDLNASGD-----GGMLDTFLPVN---GRKLK- 383

  Fly   638 CKASLTHKTELMTKLEVQKEDMASTIDQLEKKWSHDKSNLGEILKTTSQTLTTQVTASEER---- 698
                  .:..|...:.:..|..:||.......|. .:.:.|:...:|:.:.:..:|...::
  Fly   384 ------KQHTLFEGVSMLDEAASSTACISSAPWD-IQGSAGDSTTSTTASSSVSITPGSDKMDQQ 441

  Fly   699 --------AARAEAESRIERE---WRIS----LQEKELKLKEKIA-------------NLQGCLK 735
                    :.:....:::|:|   :|||    ...:.:|...::|             ||....:
  Fly   442 SLASFLQMSRQTHNNTQLEKENAHFRISEACITAIEHVKWSRRLATPAGPTSHNLSEPNLMPYAE 506

  Fly   736 ELSEEKERNGKLKADLDKVRTQWSEAQTTLEELGIQLSVSKLK--VSEMQ-----------DQER 787
            ::.....:|...:|...::.:::||.|  |..||      .||  |||.:           .|:.
  Fly   507 QIPGGGMQNHSAEAVGLQLISRFSEQQ--LPRLG------HLKWLVSEQEAPQQLLPLPTPKQDH 563

  Fly   788 RQRQLLSGSAQSLQAMPEAVGSPGIWAP---DSIATHCTACEREFNLTRRKHHCRSC-------- 841
            .|..|..|::.              |||   ..|.|...:..|...|.::.|.|..|
  Fly   564 EQASLTRGTSS--------------WAPPRQQIIFTEHPSESRSKVLQKQNHRCAGCGMRVAKHL 614

  Fly   842 ----------GEIFCKACSEHTLPLLNAQGQPGKPVRVCD-NCY 874
                      |:..|..|..:.:..:     |.:.:|..| .||
  Fly   615 QQHFRYCTYLGKYLCTGCHRNQISAI-----PARILRSWDFRCY 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31064	NP_001287560.1	RUN_RUFY1_like	281..436	CDD:439043	36/155 (23%)
		Smc	<562..>807	CDD:440809	52/320 (16%)
		FYVE_RUFY1_like	813..874	CDD:277261	16/82 (20%)
Rubicon	NP_572496.1	RUN_RUBCN	50..207	CDD:439048	41/170 (24%)
		zf-RING_9	619..824	CDD:464030	8/40 (20%)