Protein Alignment CG31064 and Zfyve26

DIOPT Version :10

• Sequence 1: NP_001287560.1
• Gene: CG31064 / 43277
• FlyBaseID: FBgn0051064
• Length: 877
• Species: Drosophila melanogaster
• Sequence 2: XP_038968219.1
• Gene: Zfyve26 / 314265
• RGDID: 1307820
• Length: 2544
• Species: Rattus norvegicus
• Alignment Length: 1147
• Identity: 221/1147 - (19%)
• Similarity: 355/1147 - (30%)
• Gaps: 429/1147 - (37%)

  Fly     5 VEDTKRTKLSSANNNNLSSTSGSGRIKSSSLATGSSASGS----------------SSKPL---- 49
            ||.....:.|...||.:..| ||||  |:..|.||:|:..                |..|:
  Rat   881 VEHKIENQNSDGGNNTVRRT-GSGR--STLQAIGSAAAAGMVFYSISDVTDKLLSPSEDPIPTLQ 942

  Fly    50 --------RSAVKTPTSGSATSLSSGTMAAKKAPQTGQQQVGKSAKSATAATPTGTTATAIGATA 106
                    .:...||..|....||...|||... ...|.|:.|:.|.....
  Rat   943 EDFWINAALTETNTPLRGVLEDLSPPAMAAFDL-ACCQCQLWKTCKQLLET-------------- 992

  Fly   107 TTRAQAAAAKSQKGQNPPSQQVQPKQQPPQPQQTQQQPLVLQQQQASNSSNTIALPKA----SHA 167
               |:...:.|.:|:.....||     ...|...:..|.||||     .|..::.|..    :.:
  Rat   993 ---AERRLSSSLEGRGRRLDQV-----VLNPDGMRGFPFVLQQ-----ISKILSYPLTVTGLTKS 1044

  Fly   168 NTSEELAGG-----VQDTIYLCNFRVSVDGEWLCLKELQDIDVAGGTGNQAAQTSEKLAGGSSSQ 227
            .|.||..||     :.:.:.:|         |..|.|    |......:.:.|..:.|
  Rat  1045 ETLEERGGGAPRCSISELLQMC---------WPSLTE----DCIASHTSLSQQLDQAL------- 1089

  Fly   228 TGGFGSNYNVGSSSSKRNSKRFSGLSTGSGSGGNAGGGGGLDITDNARDTAEIERSNLVNICKLV 292
                         .|.|.:...||                            .|..:....|
  Rat  1090 -------------QSLREALTLSG----------------------------TEPKSTPLTC--- 1110

  Fly   293 VKELLEQSLRYGRMLDSD--HLPLQHFFIVIEHVLGHGLRPKKGLLGPRKELWDLLQSVEHYCPE 355
               |:||:.:.....::.  |:..|    :::..||     |:.|.|||:.  |.:.:...||..
  Rat  1111 ---LVEQAAQKAPEAEAHPVHIQSQ----LLQKTLG-----KQTLAGPRQT--DYVGAFFSYCSS 1161

  Fly   356 -AQDITASVRDLP-TVRTHIGRARAWLRIALMQKKLSDYLQALIEHRE---DSLFDYYEPHALMM 415
             |:.:..|:...| .|...:|..     ..|:|:..|..:..|:..|:   |.|       |.::
  Rat  1162 LAKVLLRSLSSDPDNVEVKVGNP-----FVLLQQSSSQLVSHLLLERQVPPDRL-------AALL 1214

  Fly   416 SDEIVVIMGILVGLNVIDC-----NLCVKEEDLDSQQG-----------------VIDFSLYLR- 457
            :.|   .:.:.|...::.|     .||:..:   |||.                 ::| .|.|.
  Rat  1215 AQE---HLNLSVPQVIVSCCCEPLTLCLSRQ---SQQASSLTAHLGMLAQGHASHLLD-GLPLSV 1272

  Fly   458 ----------SSSRNADAAPEDSAPPALLDATGQGNMIAVLDQKNYIEELNRHLNATVG------ 506
                      |:.|.:|::|:||.|.....|      :|.|..::.|..:...|.|:.|
  Rat  1273 LGSPRPSENPSAERKSDSSPKDSLPAFTASA------LAFLKSRSKILAMVACLRASRGTKVSRP 1331

  Fly   507 -----NLQAKVESLTTTNAL------MKEDLAIARNSLLA----LQAENQAMRQSTSAG----DN 552
                 .|:.:.|:..|...:      :.|...:...:|||    ||..::: |.|.:|.    ..
  Rat  1332 SLSWKELRGRREAPLTAEKVAQECEHLLEQFPVFEAALLANWEPLQQASES-RPSLAASLCGQAR 1395

  Fly   553 NSTGSGGSSDKDKEKASEELVEERRKNSELEKELKLQVSLKAESDMAMKLLEKDIHEKQDTIVSL 617
            .||...|......:....|..||.....:..:.|:|......:||        |:...:|::::.
  Rat  1396 LSTVLLGLHSTLAQDVVTEAFEEALVARDWPRALQLIDVYGQDSD--------DLSSVRDSVLTC 1452

  Fly   618 RRQLD--------DIK------QINLEMYRK--LQDCKASLTH-----------KTEL---MTKL 652
            ....|        .:|      |:.|....|  |:.|...|.:           |:||   :|:|
  Rat  1453 ATVCDKEGWQYLFPVKDASLRSQLALRFVDKWPLESCLEILAYCVSDMAVPEELKSELQRKLTEL 1517

  Fly   653 EVQKEDMASTIDQLEKKWSHDKSNLGEILKTTSQTLTTQVTASEERAARAE--AESRIEREWRIS 715
            .|.::.:......:...|...:|...|    ...|:...:..|:|.....|  ....|.||..:|
  Rat  1518 RVYQKILGLQDPPVWCDWQTLRSCCAE----DPSTVMDMMLGSQEYELCEEWGCLYPIPREHLVS 1578

  Fly   716 LQ-------------EKELKLKEKIANLQGCLKELSEEKERN------------------GKLKA 749
            |.             ||.|:|.::|.:...||:......:::                  |:|..
  Rat  1579 LHHKHLLYLLERREYEKALQLLQRIPDPTMCLEVTERSLDQHPSLATSHFLANYLTSHFYGELTT 1643

  Fly   750 D----------------------------------------LDKVRTQW--SEAQT--------- 763
            |                                        |..::..|  :..||
  Rat  1644 DRHHEIQALYMGSKVLLTLPEQHRASYAHLSSSPLLMLEQLLMNMKVDWATTAVQTLQQLLAGQD 1708

  Fly   764 ---TLEELGIQLSVSKLK----------------------VSEMQDQERRQRQLLSGSAQ-SLQA 802
               ||:|:...||....|                      |.:..|.|...|   |.||: |..|
  Rat  1709 IGFTLDEVDSLLSRYAGKALDLPYPLREKRSDSMIHLQEPVHQASDPETLSR---SSSAEFSAAA 1770

  Fly   803 MPEAVGSPGI---------------------------------WAPDSIATHCTACERE-FNLTR 833
            ...|..:||.                                 |.||...:.|..|.|| |.:..
  Rat  1771 AAPAPAAPGSALVCSPSPKERAFPQTQPPLEFVPPETPPARDQWVPDETESMCMVCCREHFTMFN 1835

  Fly   834 RKHHCRSCGEIFCKACSEHTLPLLNAQGQPGKPVRVCDNCYA 875
            |:||||.||.:.|.:||...:.:   :|....|.||||.||:
  Rat  1836 RRHHCRRCGRLVCGSCSTKKMVV---EGCRENPTRVCDQCYS 1874

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31064	NP_001287560.1	RUN_RUFY1_like	281..436	CDD:439043	33/166 (20%)
		Smc	<562..>807	CDD:440809	64/384 (17%)
		FYVE_RUFY1_like	813..874	CDD:277261	24/61 (39%)
Zfyve26	XP_038968219.1	FYVE_ZFY26	1814..1874	CDD:277263	25/62 (40%)