Protein Alignment CG31064 and Zfyve28

DIOPT Version :9

• Sequence 1: NP_001287560.1
• Gene: CG31064 / 43277
• FlyBaseID: FBgn0051064
• Length: 877
• Species: Drosophila melanogaster
• Sequence 2: XP_006251318.1
• Gene: Zfyve28 / 305454
• RGDID: 1310151
• Length: 917
• Species: Rattus norvegicus
• Alignment Length: 881
• Identity: 160/881 - (18%)
• Similarity: 282/881 - (32%)
• Gaps: 325/881 - (36%)

  Fly   282 RSNLVNICKLVVKELLEQS-------LRYGRMLDSDHLPLQHFF---------IVIEHVL-GHGL 329
            :.|::||...:::|.:.|.       :::...:..|:|..|.:|         |::...| ...:
  Rat    60 QDNVLNIINQIMEECIPQDRAPRDFCVKFPEEIRHDNLAGQLWFGAECLAAGSIIMNRELESMAM 124

  Fly   330 RPKKGLLGPRKELWDLLQSVEHYCPEAQDITASVRD--LPTVRTHIGRARAWLR---IALMQKKL 389
            ||.      .||   |.:|:|       |:..::||  |..:.|:..:.|..||   :...:.:|
  Rat   125 RPL------AKE---LTRSLE-------DVRGTLRDQALRDLNTYTEKMREALRRFDVLFAEFEL 173

  Fly   390 SDYLQALI---EHRE-------------------------DSLFDYYEPHALMMSDEIVVIMGIL 426
            | |:.|::   ..||                         ..:.|.|||..:.....:.::.|::
  Rat   174 S-YVSAMVPVKSPREYYVQQEVIVLFCETVERALEFGYLTQDMIDDYEPALMFTIPRLAIVCGLV 237

  Fly   427 V---------------------------------------GLNVIDCNLCVKEEDLDSQQGVIDF 452
            |                                       .|:.::.:|||.:          |.
  Rat   238 VYADGPLNLDRKVEDMSELFRPFHTLLRKIRDLLQALTEEELHTLERSLCVSQ----------DV 292

  Fly   453 SLYLRSSSRNADA-APEDS---APPALLDATGQGNMIAVLDQKNY----IEELNRHLN------- 502
            .|.:|:.::...| ||..|   ||...|.|:.......:.....|    :|||:|.::
  Rat   293 ELPIRADAQAPSALAPSFSASLAPEETLSASANNPEEELACSMQYDDQELEELSRMVHRAGDEMS 357

  Fly   503 -------------------------ATVGNLQAKVESLTTTNALMKEDLAIARNSLLALQAENQA 542
                                     |:....|.|..|.........:|:.:..:   ..:.|:..
  Rat   358 SLLSPPSACQSPAHRAGSEASPRGEASPARAQLKSGSDEEERVFFMDDVEVTES---PARPESPR 419

  Fly   543 MRQSTSAGDNNSTGSGGSSDKDKEKASEELVEERRKNSELEKELKLQVSLKAESDMAMKLLEKDI 607
            .....:.|:....|..|.|.:...:|...:.||...|:.:|.: |::::..|.| .:...|:..:
  Rat   420 STFELTQGNVQQRGQDGQSGEVGVRAPALVKEEDWSNNNIEGD-KIKLASLAGS-TSCSCLDSQL 482

  Fly   608 H--------EKQDTIVSLRRQLDDIKQ-----INLEMYRKLQDCKASLTHKTELMTKLEVQKEDM 659
            :        |..:|...:..:...:|.     .|.:....|....||.......::.||.:.|..
  Rat   483 YLDGWEVSAEDAETAEMIAHRTGGMKLSATVIFNPKSPTSLDSAAASQEVPGHSISPLEPRAEGT 547

  Fly   660 ASTIDQLEKKWSH------------------------DKSNLGEILKTTSQTLTTQVTASEERAA 700
            .....:|....::                        :|...|.:|..::.:::......:|...
  Rat   548 GDNTHKLSTTATNCLLHSCVCCGSCGDSREDAVECLREKCGPGSVLSASNPSVSLAKGGEKEPER 612

  Fly   701 RAEAES---RIEREWRISLQEKELKLKEK-IANLQG----CLKELSEEKERNGKLKADLDKVRTQ 757
            ..||:.   .:..|...|.||.:.....| :|:..|    ....|..|.|..|:.:.:   .|.|
  Rat   613 LEEAQPSDVTLPAEDASSRQEPKAPASNKCLAHTSGPQVDTASRLQGESEVKGQPEPE---ARKQ 674

  Fly   758 WSE--------------AQT---------------------------TLEELGIQLSVSKLKVSE 781
            .||              |||                           :|:...::::.:.:.|:.
  Rat   675 DSEKSPVVSGDSPRGDTAQTEPQHLSGSRAGDRTQGLALPSSTTGSCSLDSTRLEVTTAVMPVTP 739

  Fly   782 MQDQERRQRQL-------------LSGSAQSLQA------------------------------- 802
            |..:|:.:.:.             :||.|..||.
  Rat   740 MATREKIRSRFHGSHDLIHRLFVCISGVADQLQTNYASDLRSILKTLFEVMATKPETDDKEKLKK 804

  Fly   803 ---------------MPEAVGS--------------PGIWAPDSIATHCTACEREFNLTRRKHHC 838
                           ..|.|.|              |..|.||.....||:|:..|.:.||||||
  Rat   805 VTQSLRSAALEDCALCQETVSSSELAAKTRDGDFEDPPEWVPDEACGVCTSCKAPFTVIRRKHHC 869

  Fly   839 RSCGEIFCKACSEHTLPLLNAQGQPGKPVRVCDNCY 874
            ||||:|||..||.|:.| |...||. ||||||.:||
  Rat   870 RSCGKIFCSRCSSHSAP-LPRYGQV-KPVRVCTHCY 903

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31064	NP_001287560.1	RUN	316..439	CDD:280855	33/204 (16%)
		CASP_C	495..>634	CDD:285395	27/183 (15%)
		FYVE_RUFY1_like	813..874	CDD:277261	33/60 (55%)
Zfyve28	XP_006251318.1	FYVE_LST2	840..904	CDD:277270	36/66 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343792
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840