Protein Alignment CG31064 and lst-2

DIOPT Version :9

• Sequence 1: NP_001287560.1
• Gene: CG31064 / 43277
• FlyBaseID: FBgn0051064
• Length: 877
• Species: Drosophila melanogaster
• Sequence 2: NP_508756.2
• Gene: lst-2 / 180712
• WormBaseID: WBGene00003084
• Length: 661
• Species: Caenorhabditis elegans
• Alignment Length: 667
• Identity: 139/667 - (20%)
• Similarity: 237/667 - (35%)
• Gaps: 215/667 - (32%)

  Fly   267 GLDITDNARDTAEIERSNLVNICKLVVKE-------LLEQSLR----YGRMLDSDHLPLQHFFIV 320
            |.:|.|:     |.|...:..:.|.|.|:       |..||||    |..::..:.|.....|..
 Worm   112 GSNIIDH-----ETESDLIRPLAKDVTKQLDFLRDLLKNQSLRDPSAYNPVIKENLLKFDKLFAE 171

  Fly   321 IEHVLGHGLRPKKGLLGPRKELWDLLQSVEHYCPEAQDITASVRDLPTVRTHIGRARAWLRIALM 385
            .|:.....:.|.|.:             .||         .|..|:..:.:.:      |.:||:
 Worm   172 FEYQYVSAMVPVKSV-------------KEH---------DSQLDVAVLFSEV------LSLALV 208

  Fly   386 QKKLSDYLQALIEHREDSLFDYYEPHALMMSDEIVVIMGILVGLNVIDCNLCVKEEDLDSQQGVI 450
            :..::           ..|.||.:|..::....:.::.|:||..|.. .|:.|..|:| |:....
 Worm   209 KDLIT-----------QDLIDYCDPSVMIAIPRLGIVWGLLVYSNGA-LNVDVPAENL-SEMFRP 260

  Fly   451 DFSLYLRSSS------------------RNADAAPEDSAPPALL-----DATGQGNMIAVLDQKN 492
            .:||.::..:                  :...|.|||::....:     :||.:..  |..:|:.
 Worm   261 FYSLLVKIRNLLRILTPTELTKLETVLCKGESAVPEDTSSTLTMSDFRTNATDEEK--AKNNQRV 323

  Fly   493 YIEELNRHLNATVGNLQAKV-ESLTTTNALMKEDLAIARNSLLALQAENQAMRQSTSAGDNNSTG 556
            ::.::.   :.:..:|.:.| :|.:.|.:|....||...:.     :|....:.....||:.:.|
 Worm   324 WMCDMP---SDSTSSLDSSVQDSSSETTSLASSALASPHSG-----SEENVSQIENEEGDDEAIG 380

  Fly   557 SGGSSDK---------------DKEKASEELV----EERRKNSELEKELKLQVS--LKAESD--M 598
            :..:|..               |.|::||..|    :|.|..|:.|....:|.|  |:.|:.  .
 Worm   381 TNSNSSNEVTESPETIEEPDNVDMEESSESEVDTHIDETRNESDDEITDDVQASDVLQVETKKCK 445

  Fly   599 AMKLLEKDIHEKQ-DTIVSLRRQLDDIKQINLEMYRKLQDCKASLTHKTELMTKLEVQKEDMAST 662
            :.:|||:...:|. .||:.:  |.|...||:.:..|........|.|:..:.         :|..
 Worm   446 SSRLLEQKKFDKSVKTIIPM--QTDPRSQIDPKNLRSRFRSSEDLVHRLFVC---------IAGV 499

  Fly   663 IDQLEKKWSHDKSNLGEILKTTSQTLTTQVTASEERAARAEAESRIEREWRISLQEKELKLKEKI 727
            .|||:..:|                                  |.|.:..::.||..|:....::
 Worm   500 ADQLQTNYS----------------------------------SEIRKVLKLILQPSEIIPVYEV 530

  Fly   728 ANLQGCLKELSEEKERNGKLKADLDKVRTQWSEAQTTLEELGIQLSVSKLKVSEMQDQERRQRQL 792
            .|                          .|.:.:||..||.|::
 Worm   531 VN--------------------------AQVANSQTEGEETGVE--------------------- 548

  Fly   793 LSGSAQSLQAMPEAVGSPGIWAPDSIATHCTACEREFNLTRRKHHCRSCGEIFCKACSEHTLPLL 857
                ||....:|..:|..  |.||.....||||...||..||:||||:||.|||..||.:|:. :
 Worm   549 ----AQETLPLPAFMGVR--WVPDEDCEQCTACSMPFNFVRRRHHCRNCGRIFCHKCSCNTIS-I 606

  Fly   858 NAQGQPGKPVRVCDNCY 874
            ...|...| ||||:.||
 Worm   607 PEHGYDRK-VRVCNLCY 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31064	NP_001287560.1	RUN	316..439	CDD:280855	20/122 (16%)
		CASP_C	495..>634	CDD:285395	35/163 (21%)
		FYVE_RUFY1_like	813..874	CDD:277261	29/60 (48%)
lst-2	NP_508756.2	SDA1	<361..>453	CDD:283052	21/96 (22%)
		FYVE_LST2	559..623	CDD:277270	32/68 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2108
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940