Protein Alignment CG31064 and zfyve28b

DIOPT Version :10

• Sequence 1: NP_001287560.1
• Gene: CG31064 / 43277
• FlyBaseID: FBgn0051064
• Length: 877
• Species: Drosophila melanogaster
• Sequence 2: XP_002936998.2
• Gene: zfyve28b / 100493455
• XenbaseID: XB-GENE-25919023
• Length: 580
• Species: Xenopus tropicalis
• Alignment Length: 649
• Identity: 129/649 - (19%)
• Similarity: 238/649 - (36%)
• Gaps: 186/649 - (28%)

  Fly   309 SDHLPLQHFFIVIEHVLGHGLRPKKGLLGPRKELWDLLQSVEHYCPEAQDITASVRDLPTVRTHI 373
            ||...|..||.|.|.|        .|::...:.| ||.:..::|......:.:|...:      :
 Frog    16 SDPRLLAKFFYVNEEV--------SGIVNELESL-DLRKDPQNYLVLLNQLHSSQERM------L 65

  Fly   374 GRARAWLRIALMQKKLS-DYLQALIEHREDSLFDYYEPHALMMSDEIVVIMGILVGLNVIDCNLC 437
            |.....:.:.:..|:.. ||   |::..::...:....|.|..::       :|||...|:
 Frog    66 GVIEQIMELCVPTKRQQRDY---LLKFPDEVAHENMTTHLLFSAE-------LLVGGTYIE---- 116

  Fly   438 VKEED--------LDSQQGVIDFSLYLRSSSRNADAAPEDSAPPALLDATGQGNMIAVLDQKNYI 494
            |:|.|        .:..:.:.|....||..|.....:..::...|||
 Frog   117 VEEADGSLLRPLAQELLRSLADLRFALREQSFEDPGSYPETIHKALL------------------ 163

  Fly   495 EELNRHLNATVGNLQAKVESLTTTNALMKEDLAIARNSLLALQAENQAMRQSTSAGDNNSTGSGG 559
                 |.:|.....:.:..||..:....:|..:....::|..:..::|::
 Frog   164 -----HYDALCAEFELRYVSLLVSVKTPEEIYSQQEVAVLFCETVSRALK--------------- 208

  Fly   560 SSDKDKEKASEELVEERRKNSELEKELKLQVSLKAESDMAMKLLEKDIHEKQDTIVSLRRQLDDI 624
                 |...::|:::      ..|.||.:.:...|        :...:....|..::|::|.:::
 Frog   209 -----KGYLTQEMID------HCEPELMISIPRLA--------IISGLLIYPDGPLNLQKQPEEM 254

  Fly   625 KQINLEMYR-------KLQDCKASLTHKTELMTKLE-----VQKEDMA---STIDQLEKKWSHDK 674
                .|::|       |:|:....||.: ||:: ||     ...:|.:   |.|.:...||:...
 Frog   255 ----CELFRPFHGLLKKIQELLCILTEQ-ELIS-LERALCCASSDDPSGHLSAISESPNKWNFIS 313

  Fly   675 SNLGEILKTTSQTLTTQVTASEERAARAEAESRIEREWRISLQ-EKELKLKEKIANL-------- 730
            ...|    |.|:..:|.:..||.  .|.|..|..|.. .||:| :..:.:....|:.
 Frog   314 HATG----TPSEPKSTIMGISEN--PRPEVPSTWETH-SISIQCQSPVTIHSNYASNYCKSDRSN 371

  Fly   731 -----QGCLKELSEEKERNGKLK-----------------ADLDKVRTQWSEAQTTLEELGIQLS 773
                 ||.:|.:..|...|.:.:                 ..|..||:::......|..|.:.::
 Frog   372 RTYRDQGIIKTVGFEHSGNAETEYARSQHHNQHVKYAHRNLRLQHVRSRYRSDSDMLHRLFVCIA 436

  Fly   774 ----------VSKLKV------SEMQDQERRQRQLLSGSA----------QSLQAMPEAVGSPGI 812
                      .|.|:|      ..:..:::.:|:..:.:|          .:::....|...|..
 Frog   437 GVADQLQTNFASDLRVILKTVFETVSSKQQEEREKTTDNAFRLSDCHLCQSNIEHHTVAKSVPPE 501

  Fly   813 WAPDSIATHCTACEREFNLTRRKHHCRSCGEIFCKACSEH--TLPLLNAQGQPGKPVRVCDNCY 874
            |.||:.::.|.:|...|.|.||:|||||||:|||..||.:  |||.|.:.    .|||||.:||
 Frog   502 WLPDNASSQCMSCYASFTLLRRRHHCRSCGKIFCSRCSAYSSTLPYLVST----HPVRVCSHCY 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31064	NP_001287560.1	RUN_RUFY1_like	281..436	CDD:439043	25/127 (20%)
		Smc	<562..>807	CDD:440809	53/316 (17%)
		FYVE_RUFY1_like	813..874	CDD:277261	30/62 (48%)
zfyve28b	XP_002936998.2	FYVE_LST2	499..561	CDD:277270	31/65 (48%)