DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31064 and rundc3aa

DIOPT Version :9

Sequence 1:	NP_001287560.1	Gene:	CG31064 / 43277	FlyBaseID:	FBgn0051064	Length:	877	Species:	Drosophila melanogaster
Sequence 2:	XP_001922267.3	Gene:	rundc3aa / 100148117	ZFINID:	ZDB-GENE-130530-533	Length:	424	Species:	Danio rerio

Alignment Length:	422	Identity:	106/422 - (25%)
Similarity:	182/422 - (43%)	Gaps:	105/422 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   251 GLSTGSGSGGNAGGGGGLDITDNARDTAEIERSNLVNICKLVVKELLEQSLRY-GRMLDSDHLPL 314
            ||::...|..|.|                :||.||:.:|:..||.|||   :| ...:|......
Zfish     4 GLTSKKTSSRNIG----------------VERKNLITVCRFSVKTLLE---KYTAEPIDDSSEEF 49

  Fly   315 QHFFIVIEHVLGHGLRPKKGLLGP--RKELWDLLQSVEHYCPEA-QDITASVRDLPTVRTHIGRA 376
            .:|..::||:|.|..:...|....  ::..||.::..   |.:. .:..:|:..:..:.|...:.
Zfish    50 INFAAILEHILSHRFKGPGGWFSSDGQRSFWDYIRLA---CSKVYNNCISSIESIENISTSRAKG 111

  Fly   377 RAWLRIALMQKKLSDYLQ-ALIEHREDSLFDYYEPHALMMSDEIVVIMGILVGLNVIDCNLCVKE 440
            |||:|:|||:|:||:|:. ||.:.|....|  |:..|:|:.:|..|:.|:|:||:.||.:.|:|.
Zfish   112 RAWIRVALMEKRLSEYVAIALRDTRTTRRF--YDDGAVMLREEATVLTGMLIGLSAIDFSFCLKG 174

  Fly   441 EDLDSQ-QGVIDFSLYLR-----------SSSRNADAAPEDSAP------PALLDATGQGNMIAV 487
            |.||.: ..|||::.||:           ...|:.|::..|.:.      |.:.|.....|....
Zfish   175 EVLDGKTPAVIDYTPYLKFTQSYDYLSDEEDRRSVDSSASDESVAEHPYIPLVTDEETWSNKCRK 239

  Fly   488 LD--------QKNYIEELNRHLNATVGN-------LQAKVESLTTTNALMKEDL-AIARNSLLAL 536
            ::        ||.|:|||.|...:.:.|       |.||:|.|...:...|::| ||    :|.|
Zfish   240 MEQRFKIVNAQKGYLEELVRLRESQLKNVETENKRLDAKLEELQVQSQQEKKELEAI----ILEL 300

  Fly   537 QAENQA-----------------MRQSTSAGDNNSTGSGGSSDKDKEKASEELVEERRKNSELEK 584
            ||:...                 :.|..:|...|:.|:               |:..|:.|....
Zfish   301 QAQITGIIPCEPSHLVKGLSIPLINQWATAQATNNQGN---------------VKLFRRRSFHSL 350

  Fly   585 ELKLQVSLKAESDMAMKLLEKDIHEKQDTIVS 616
            :|...:||.::|.      ::|.::..||:.|
Zfish   351 DLSADLSLNSDSQ------KEDGNQNGDTVWS 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31064	NP_001287560.1	RUN	316..439	CDD:280855	38/126 (30%)
		CASP_C	495..>634	CDD:285395	33/147 (22%)
		FYVE_RUFY1_like	813..874	CDD:277261
rundc3aa	XP_001922267.3	RUN	51..174	CDD:280855	38/127 (30%)
rundc3aa	XP_001922267.3	Prefoldin	241..>301	CDD:298833	18/63 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584055
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4381
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740