DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42813 and Nudt14

DIOPT Version :9

Sequence 1:	NP_001303547.1	Gene:	CG42813 / 43276	FlyBaseID:	FBgn0261995	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_079675.1	Gene:	Nudt14 / 66174	MGIID:	1913424	Length:	222	Species:	Mus musculus

Alignment Length:	222	Identity:	94/222 - (42%)
Similarity:	135/222 - (60%)	Gaps:	19/222 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MENVSKIWLGPLPQDSPYVKPFRLYYVQNGVEKNWDLLKVHDSVAIILYNTSRQKLVLVRQFRPA 65
            ||.:..:.:| |...|||::||.|:|.|:||:|:||.:|.||||.|:::|:||:.||||:|||||
Mouse     1 MERIDGVAVG-LCAHSPYLRPFTLHYRQDGVQKSWDFMKTHDSVTILMFNSSRRSLVLVKQFRPA 64

  Fly    66 VYHGIIS-------SAKGTFDEVDLKE-FPPAIGVTLELCAGIVDK-NKSWVEIAREEVVEECGY 121
            ||.|.:.       :|.......:|:: .|.:.||.:||||||||: ..|..|.|.:|..|||||
Mouse    65 VYAGEVERHFPGSLTAVNQDQPQELQQALPGSAGVMVELCAGIVDQPGLSLEEAACKEAWEECGY 129

  Fly   122 DVPVERIEEVMVYRSGVGSSGAKQTMYYCEVTDADKATGGGGV--DDEIIEVVELSLEEAKRMIQ 184
            .:....:..|..|.||||.:.::|||:|.|||||.:...|||:  :.|:|||:.|:|::|    |
Mouse   130 RLVPTDLRRVATYMSGVGLTSSRQTMFYAEVTDAQRGGPGGGLAEEGELIEVIHLNLDDA----Q 190

  Fly   185 QGAVNNSPPSCL---MGLMWFFANRAP 208
            ..|.|...|..|   ..:.|||:...|
Mouse   191 AFADNPDIPKTLGVIYAISWFFSQVVP 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42813	NP_001303547.1	ADPRase_NUDT5	41..205	CDD:239516	75/177 (42%)
Nudt14	NP_079675.1	TIGR00052	17..210	CDD:129162	84/196 (43%)
Nudt14	NP_079675.1	Nudix box	111..129		7/17 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837976
Domainoid	1	1.000	116	1.000	Domainoid score	I5933
eggNOG	1	0.900	-	-		E1_COG0494
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11930
Inparanoid	1	1.050	157	1.000	Inparanoid score	I4260
Isobase	1	0.950	-	0	Normalized mean entropy	S5871
OMA	1	1.010	-	-		QHG59770
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006309
OrthoInspector	1	1.000	-	-		otm42486
orthoMCL	1	0.900	-	-		OOG6_106416
Panther	1	1.100	-	-	LDO	PTHR11839
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4212
SonicParanoid	1	1.000	-	-		X6035
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740