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Protein Alignment Ser and megf10

DIOPT Version :9

Sequence 1:	NP_001287558.1	Gene:	Ser / 43275	FlyBaseID:	FBgn0004197	Length:	1407	Species:	Drosophila melanogaster
Sequence 2:	NP_001072726.1	Gene:	megf10 / 780183	XenbaseID:	XB-GENE-491974	Length:	1114	Species:	Xenopus tropicalis

Alignment Length:	1377	Identity:	305/1377 - (22%)
Similarity:	417/1377 - (30%)	Gaps:	557/1377 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 SSFVLSDPGVGAIVLPFTFRWTKSFTLILQAL------DMYNTSYPD--------AERLIEETSY 210
            ||..|.||.|.:       .| :|:::.:|..      .:|.||..|        ..|:...|:|
Frog    23 SSLNLEDPNVCS-------HW-ESYSVTVQESYSHPYDQVYYTSCTDILNWFKCTRHRISYRTAY 79

  Fly   211 SGVILPSPEWKTLDHIGRNARITYRVRVQCAVTYYNTTCTTFCRPRDDQFGHYACGSEGQKLCLN 275
            .                |..:..||.:.||...:|                      |.:::|:
Frog    80 R----------------RGEKTMYRRKSQCCPGFY----------------------ESREMCV- 105

  Fly   276 GWQGVNCEEAICKAGCDPVHGKCDRPGECECRPGWRGPLCNECMVYPGCKHGSCNGSAWKCVCDT 340
                     ..|...|  |||:|..|..|:|.|||.||.|:.                   .||.
Frog   106 ---------PHCADKC--VHGRCIAPNTCQCEPGWGGPNCSS-------------------ACDV 140

  Fly   341 -NWGGILCDQDLNFCGTHEPCKHGGTCENTAPDKYRCTCAEGLSGEQCE------IVEHPCATR- 397
             :||        ..|.:...||:|..|.   |....|.|:.|..|.:||      ...:.|..:
Frog   141 DHWG--------PHCSSRCQCKNGALCN---PITGACHCSSGYKGWRCEERCDQGTYGNDCQQKC 194

  Fly   398 PCRNGGTCTLKTSNRTQAQVYRTSHGRSNMGRPVRRSSSMRSLDHLRPEGQALNGSSSPGLVSLG 462
            .|:||.:|                                   ||:..|
Frog   195 QCQNGASC-----------------------------------DHVTGE---------------- 208

  Fly   463 SLQLQQQLAPDFTCDCAAGWTGPTCEINIDECAGG----------PCEHGGTCIDLIGGFRCECP 517
                         |.|..|:||..||   |.|..|          ||::||.|..:.|  .|.||
Frog   209 -------------CRCPPGYTGAFCE---DLCPPGKHGSQCEERCPCQNGGVCHHVTG--ECSCP 255

  Fly   518 PEWHGDVCQVDVNECEAPHSAGIAANALLTTTATAIIGSNLSSTALLAALTSAVASTSLAIGPCI 582
            ..|.|.||
Frog   256 AGWMGTVC--------------------------------------------------------- 263

  Fly   583 NAKECRNQPGSFACICKEGWGGVTCAENLDDCVGQCRNGATCIDLVNDYRCACASGFKGRDCETD 647
                  .||      |.||..|..|::   :|  ||.||.||.....  :|.|:.|:.|..|:.:
Frog   264 ------GQP------CPEGRYGRNCSQ---EC--QCHNGGTCDSATG--QCYCSPGYNGERCQEE 309

  Fly   648 ID------ECA-TSPCRNGGECVDMVGKFNCICPLGYSGSLCEEAKENCTPSPCLEG-------- 697
            ..      :|| |..|.|||:|..:.|.  |:|..||:|..||      ||. |.||
Frog   310 CPVGLYGVKCAQTCQCLNGGKCYHISGA--CLCEPGYTGERCE------TPL-CSEGTYGMKCDK 365

  Fly   698 ----HCLNT----PEGYYCHCPPDRAGKHCEQLRPLCSQPPCNEGCFANVSLATSATTTTTTTTT 754
                |...|    |....|.|.|.|:|.:|.:        .|:.|.:.......
Frog   366 KCPCHLQYTQSCHPMSGECACKPGRSGLYCNE--------TCSLGFYGEFCQQI----------- 411

  Fly   755 ATTTRKMAKPSGLPCSGHGSCEMSDVGTFCKCHVGHTGTFCEHNLNECSPNP----------CRN 809
                          ||.....:...|...|.|..|.||..|.   ..|.|..          |:|
Frog   412 --------------CSCQNGADCDSVTGKCICAPGFTGVDCS---TACPPGTYGVNCSSLCNCKN 459

  Fly   810 GGICLDGDGDFTCECMSGWTGKRCS------ERATGC-YAGQCQNGGTCMPGAPDKALQPHCRCA 867
            ..:|...||  :|.|.:||.|..||      ....|| ...||.|||.|.|      |...|.||
Frog   460 NAVCSPVDG--SCTCKAGWHGVDCSINCPRGSWGLGCNLTCQCLNGGACNP------LDGTCTCA 516

  Fly   868 PGWTGLFC----------AEAIDQC---RGQPCHNG-GTCESGAGW--FRC--VCAQGFSGPDCR 914
            |||.||.|          ...|::|   ....||.. |.|...|||  ..|  ||..|..||:|.
Frog   517 PGWRGLKCELPCQDGTYGMNCIERCDCSHADGCHPATGYCRCLAGWAGMHCDSVCPGGHWGPNCS 581

  Fly   915 I-----NVNECSPQPCQGGATCIDGIGGYSC--ICPPGRHGLRCEILLSDPKSACQNASNTISPY 972
            :     |...|||.  .|...|..|..|.:|  ||.||.:|.||       ..||....::..|.
Frog   582 LSCDCKNGASCSPD--DGICECAPGYRGTTCQRICSPGFYGHRC-------SQACPQCVHSNGPC 637

  Fly   973 TALNRSQNWL---------DIALTGRTEDDENC-NACVCEN--------GTSRCTNLWCGL---- 1015
            ..:....:.|         ::..:||.  .:|| ..|.|.|        ||.:|...|.|.
Frog   638 HHVTGQCDCLAGFMGSLCNEVCPSGRY--GKNCAGVCACTNNGTCNPIDGTCQCYPGWIGNDCSQ 700

  Fly  1016 --------PNCYKVDPLSKSSNLS---GVCKQHEVCVPALS---------------ETCLSSPCN 1054
                    |||.........:..|   |.||    |.|..:               |..|...|.
Frog   701 ACPPGHWGPNCIHTCNCHNGAYCSAYDGECK----CSPGWTGLYCTQRCPLGYYGKECTLVCQCQ 761

  Fly  1055 VRGDCRALEPSRRVAPPRLPAKSSCWPNQAVVNENCARLTILLALERVG-KGASVEGLCSLVRVL 1118
            ...||           ..:..:.:|                     |.| .|...|..|
Frog   762 NGADC-----------DHITGQCTC---------------------RTGFMGKFCEQKC------ 788

  Fly  1119 LAAQLIKKPASTFGQDPGMLMVLCD-LKTGTNDTVELTVSSS-----KLNDPQLPVAVGLLGELL 1177
                    |::::|.  |...| || |...|.|.:..|...|     ...|..:.:.||
Frog   789 --------PSASYGY--GCRQV-CDCLNNSTCDHITGTCYCSPGWKGARCDQAVMIVVG------ 836

  Fly  1178 SFRQLNGIQRRKELELQHAKLAALTSIVEVKLETARVADGSGHSLLIGVLCGVFIVLVGFSVFIS 1242
               .||.:.|              ||       .|..||......:.|::..|.:||...::||.
Frog   837 ---NLNSLSR--------------TS-------AAIPADSYQIGAIAGIIILVLVVLFLLALFII 877

  Fly  1243 LYWKQRLAYRTSSGMNLTPSL----------DALRHEEEKSNNLQNEENLRRYTNPLKGSTSSLR 1297
            ...||:........:..||::          |.|.|     ||:.| .|.:.::||...:.|  :
Frog   878 YRQKQKGKDTAMPAVAYTPAVRVLSTDYTIADTLPH-----NNVVN-ANSQYFSNPSYHTLS--Q 934

  Fly  1298 AATGMELSLNPAPELAASAASSSALHRSQPLFPPCDFERELDSSTGLKQAHKRSSQILLHKTQNS 1362
            ..||.:  :|....:..|.:.||.|..:.....|......:| .||...|..:....|    ..:
Frog   935 CTTGPQ--VNSMDRMMVSRSKSSQLFVNLKNLDPGKRSHTID-YTGTLPADWKQGGFL----NEN 992

  Fly  1363 DMRKNTVGSLDS 1374
            .:.||:..|:.:
Frog   993 GLLKNSAYSIST 1004

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.