| Sequence 1: | NP_001287558.1 | Gene: | Ser / 43275 | FlyBaseID: | FBgn0004197 | Length: | 1407 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_077719.2 | Gene: | NOTCH2 / 4853 | HGNCID: | 7882 | Length: | 2471 | Species: | Homo sapiens |
| Alignment Length: | 965 | Identity: | 290/965 - (30%) |
|---|---|---|---|
| Similarity: | 393/965 - (40%) | Gaps: | 217/965 - (22%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 208 TSYSGVIL--------PSPEWKTLDHIGRNARITYRVRVQC--AVTYYNTTCT-----TFCRPRD 257
Fly 258 DQFGHYACGSEGQKLCL-NGWQ--------GVNCEEAICKAGCDP-VHGKCDRPG----ECECRP 308
Fly 309 GWRGPLC------------------------------------------NECMVYPGCKHGSCNG 331
Fly 332 --SAWKCVCDTNWGGILCDQDLNFCGTHEPCKHGGTCENTAPDKYRCTCAEGLSGEQCEIVEHPC 394
Fly 395 ATRPCRNGGTCTLKTSNRTQAQVYRTSHGRSNMGRPVRRSSSMRSLDHLRPEGQALNGSSSPGLV 459
Fly 460 SLGSLQLQQQLAPDFTCDCAAGWTGPTCEINIDECAGGPCEHGGTCIDLIGGFRCECPPEWHGDV 524
Fly 525 CQVDVNECEAPHSAGIAANALLTTTATAIIGSNLSSTALLAALTSAVASTSLAIGPCINAKECRN 589
Fly 590 QPGSFACICKEGWGGVTCAENLDDCVGQ-CRNGATCIDLVNDYRCACASGFKGRDCETDIDECAT 653
Fly 654 SPCRNGGECVDMVGKFNCICPLGYSGSLCEEAKENCTPSPCL-EGHCLNTPEGYYCHCPPDRAGK 717
Fly 718 HCEQLRPLCSQPPC-NEG----------CFANVSLATSATTTTTTTTTATTTRKMAKPSGLPCSG 771
Fly 772 HGSCEMSDVGTFCKCHVGHTGTFCEHNLNECSPNPCRNGGICLDGDGDFTCECMSGWTGKRCSER 836
Fly 837 ATGCYAGQCQNGGTCMPGAPDKALQPHCRCAPGWTGLFCAEAIDQC-RGQPCHNGGTCESGAGWF 900
Fly 901 RCVCAQGFSGPDCRINVNECSPQPC--QGGATCIDGIGGYSCICPPGRHGLRCEILLS-DPKSAC 962
Fly 963 QNASNTISPYTALNRSQNWLDIALTGRTEDDENCNACVCENGTS--RCTNLWCGLPNCYKVDP-L 1024
Fly 1025 SKSSNLSGVCKQHEVCVPALSETCLSSPCNVRGDCRALEPSRRVAPPRLPAKSSC 1079 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Ser | NP_001287558.1 | MNNL | 83..161 | CDD:284966 | |
| DSL | 220..282 | CDD:279722 | 16/77 (21%) | ||
| EGF_CA | 350..388 | CDD:238011 | 17/37 (46%) | ||
| EGF_CA | 490..526 | CDD:238011 | 15/35 (43%) | ||
| EGF_CA | 610..645 | CDD:238011 | 15/35 (43%) | ||
| EGF_CA | 647..683 | CDD:238011 | 18/35 (51%) | ||
| EGF_CA | 798..833 | CDD:238011 | 15/34 (44%) | ||
| EGF_CA | 879..913 | CDD:238011 | 16/34 (47%) | ||
| EGF_CA | 916..952 | CDD:238011 | 12/37 (32%) | ||
| VWC_out | <993..1053 | CDD:214565 | 16/62 (26%) | ||
| NOTCH2 | NP_077719.2 | EGF_CA | 182..218 | CDD:238011 | |
| EGF_CA | 260..296 | CDD:238011 | |||
| EGF_CA | 298..335 | CDD:238011 | |||
| EGF_CA | 415..454 | CDD:238011 | |||
| EGF_CA | 456..492 | CDD:238011 | |||
| EGF_CA | 495..530 | CDD:238011 | |||
| EGF_CA | 532..568 | CDD:238011 | 3/7 (43%) | ||
| EGF_CA | 570..604 | CDD:238011 | 8/49 (16%) | ||
| EGF_CA | 608..643 | CDD:238011 | 10/34 (29%) | ||
| EGF_CA | 645..679 | CDD:238011 | 10/34 (29%) | ||
| EGF_CA | 682..717 | CDD:238011 | 0/34 (0%) | ||
| EGF_CA | 757..793 | CDD:238011 | 17/37 (46%) | ||
| EGF_CA | 795..831 | CDD:238011 | 12/57 (21%) | ||
| EGF_CA | 873..909 | CDD:238011 | 15/35 (43%) | ||
| EGF_CA | 911..947 | CDD:238011 | 12/79 (15%) | ||
| EGF_CA | 949..985 | CDD:238011 | 15/35 (43%) | ||
| EGF_CA | 987..1022 | CDD:238011 | 18/34 (53%) | ||
| EGF_CA | 1026..1061 | CDD:238011 | 13/34 (38%) | ||
| EGF_CA | 1117..1147 | CDD:238011 | 9/30 (30%) | ||
| EGF_CA | 1151..1185 | CDD:238011 | 14/33 (42%) | ||
| EGF_CA | 1188..1223 | CDD:238011 | 15/38 (39%) | ||
| EGF_CA | 1225..1262 | CDD:238011 | 16/36 (44%) | ||
| EGF_CA | 1264..1302 | CDD:238011 | 12/37 (32%) | ||
| EGF_CA | <1312..1343 | CDD:238011 | 9/49 (18%) | ||
| Notch | 1423..1456 | CDD:278494 | |||
| Notch | 1463..1497 | CDD:278494 | |||
| Notch | 1501..1534 | CDD:278494 | |||
| NOD | 1540..1591 | CDD:284282 | |||
| NODP | 1620..1673 | CDD:284987 | |||
| Ank_2 | <1820..1907 | CDD:289560 | |||
| ANK repeat | 1827..1874 | CDD:293786 | |||
| ANK | 1872..1997 | CDD:238125 | |||
| ANK repeat | 1877..1907 | CDD:293786 | |||
| Ank_2 | 1881..1974 | CDD:289560 | |||
| ANK | 1938..2062 | CDD:238125 | |||
| ANK repeat | 1943..1974 | CDD:293786 | |||
| Ank_2 | 1948..2040 | CDD:289560 | |||
| ANK repeat | 1976..2007 | CDD:293786 | |||
| ANK repeat | 2009..2040 | CDD:293786 | |||
| Chorion_3 | <2292..2421 | CDD:253174 | |||
| DUF3454 | 2381..2444 | CDD:288764 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 47 | 1.000 | Domainoid score | I12003 |
| eggNOG | 1 | 0.900 | - | - | E33208_3BAFT | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.810 | |||||