DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser and Egfl8

DIOPT Version :9

Sequence 1:	NP_001287558.1	Gene:	Ser / 43275	FlyBaseID:	FBgn0004197	Length:	1407	Species:	Drosophila melanogaster
Sequence 2:	NP_001004070.1	Gene:	Egfl8 / 406166	RGDID:	1549706	Length:	291	Species:	Rattus norvegicus

Alignment Length:	109	Identity:	39/109 - (35%)
Similarity:	53/109 - (48%)	Gaps:	19/109 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   585 KECRNQPGSFACICKEGW-----GGVTCAENLDDCVGQCRNGATCIDLVNDYRCACASGFKGRDC 644
            :|.|.:......:|.:||     |.:|| |.:  |...|.||..|   ....:|.||||:.|:.|
  Rat    82 REVRREVQQTHVVCCQGWKKPHPGALTC-EAI--CSKPCLNGGVC---AGPDQCECASGWAGKHC 140

  Fly   645 ETDIDECATS--PCRNGGECVDMVGKFNCICP----LGYSGSLC 682
            ..|:|||.||  .|.:|  |::.:|.|.|.||    ||..|..|
  Rat   141 HVDVDECRTSLTLCSHG--CLNTLGSFTCSCPNPLVLGPDGRAC 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser	NP_001287558.1	MNNL	83..161	CDD:284966
		DSL	220..282	CDD:279722
		EGF_CA	350..388	CDD:238011
		EGF_CA	490..526	CDD:238011
		EGF_CA	610..645	CDD:238011	11/34 (32%)
		EGF_CA	647..683	CDD:238011	18/42 (43%)
		EGF_CA	798..833	CDD:238011
		EGF_CA	879..913	CDD:238011
		EGF_CA	916..952	CDD:238011
		VWC_out	<993..1053	CDD:214565
Egfl8	NP_001004070.1	EMI	36..100	CDD:400092	4/17 (24%)
		vWFA	<108..181	CDD:412136	32/80 (40%)
		EGF_CA	143..>170	CDD:214542	12/28 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910