Protein Alignment Ser and Dlk2

DIOPT Version :9

• Sequence 1: NP_001287558.1
• Gene: Ser / 43275
• FlyBaseID: FBgn0004197
• Length: 1407
• Species: Drosophila melanogaster
• Sequence 2: XP_017451911.1
• Gene: Dlk2 / 316232
• RGDID: 1309143
• Length: 405
• Species: Rattus norvegicus
• Alignment Length: 519
• Identity: 126/519 - (24%)
• Similarity: 171/519 - (32%)
• Gaps: 212/519 - (40%)

  Fly   272 LCLNGWQGVNCEEAICKAGCDPVHGKCDRPGECECRPGWRGPLCNECMVYPGCKHGSCNGSAWKC 336
            ||:.|..........|.:.||..||.|...|.|.|.|||.|..|..|:..|||:||:|: ..|:|
  Rat    37 LCILGATSQPARADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGCQHGTCH-QPWQC 100

  Fly   337 VCDTNWGGILCDQDLNFCGTHEPCKHGGTCENTAPDKYRCTCAEGLSGEQCEIVEHPC--ATRPC 399
            :|.:.|.|..||:|.:.|.:..||::||.|......:|.|.|..|..|..||....||  |..||
  Rat   101 ICHSGWAGKFCDKDEHICTSQSPCQNGGQCVYDGGGEYHCVCLPGFRGRGCERKAGPCEQAGFPC 165

  Fly   400 RNGGTCTLKTSNRTQAQVYRTSHGRSNMGRPVRRSSSMRSLDHLRPEGQALNGSSSPGLVSLGSL 464
            :|||.|                  :.|                   :|.|||
  Rat   166 QNGGQC------------------QDN-------------------QGFALN------------- 180

  Fly   465 QLQQQLAPDFTCDCAAGWTGPTCEINIDECAGGPCEHGGTCIDLIGGFRCECPPEWHGDVCQVDV 529
                     |||.|.||:.|..||:|:|:|...|
  Rat   181 ---------FTCRCLAGFMGAHCEVNVDDCLMRP------------------------------- 205

  Fly   530 NECEAPHSAGIAANALLTTTATAIIGSNLSSTALLAALTSAVASTSLAIGPCINAKECRNQPGSF 594
                                                                             
  Rat   206 ----------------------------------------------------------------- 205

  Fly   595 ACICKEGWGGVTCAENLDDCVGQCRNGATCIDLVNDYRCACASGFKGRDCETDIDECATSPCRNG 659
                                   |.|||||||.:|.:.|.|..||.||.|..::|:||:.||:.|
  Rat   206 -----------------------CANGATCIDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRG 247

  Fly   660 GECVDMVGKFNCICPLGYSGSLCEEAKENCTPSPCLEGHCLNTPEGYYCHCP------------P 712
            ..|.|.|..|:|:||.||.|..||..    .|:|  :...:.||:     .|            |
  Rat   248 ARCRDRVHDFDCLCPSGYGGKTCELV----LPAP--DPATIGTPQ-----APASAVVVPATGSAP 301

  Fly   713 DRAGKHCEQL--RPLCSQPPCNEGCFANVSLA-----TSATTTTTTTTTATTTRKMAKPSGLPC 769
            ..||....::  :.:..:.....|..:.|:|.     |:|....|...|....|:...|:| ||
  Rat   302 HSAGAGLLRISVKEVVRRQEAGLGESSLVALVVFGSLTAALVLATVLLTLRAWRRGICPTG-PC 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser	NP_001287558.1	MNNL	83..161	CDD:284966
		DSL	220..282	CDD:279722	3/9 (33%)
		EGF_CA	350..388	CDD:238011	12/37 (32%)
		EGF_CA	490..526	CDD:238011	4/35 (11%)
		EGF_CA	610..645	CDD:238011	15/34 (44%)
		EGF_CA	647..683	CDD:238011	16/35 (46%)
		EGF_CA	798..833	CDD:238011
		EGF_CA	879..913	CDD:238011
		EGF_CA	916..952	CDD:238011
		VWC_out	<993..1053	CDD:214565
Dlk2	XP_017451911.1	EGF_CA	112..152	CDD:238011	13/39 (33%)
		EGF_CA	<164..195	CDD:238011	18/89 (20%)
		EGF_CA	197..233	CDD:238011	19/154 (12%)
		EGF_CA	235..271	CDD:238011	16/35 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000