Protein Alignment Ser and egas-1

DIOPT Version :9

• Sequence 1: NP_001287558.1
• Gene: Ser / 43275
• FlyBaseID: FBgn0004197
• Length: 1407
• Species: Drosophila melanogaster
• Sequence 2: NP_001359624.1
• Gene: egas-1 / 180219
• WormBaseID: WBGene00013486
• Length: 922
• Species: Caenorhabditis elegans
• Alignment Length: 587
• Identity: 151/587 - (25%)
• Similarity: 215/587 - (36%)
• Gaps: 158/587 - (26%)

  Fly   535 PHSAGIAANALLTTTATAIIGSNLSSTALLAALTSAVASTSLAIGPCINAKECRNQPGSFACICK 599
            ||.   .||..|.|..|                |:.|:||::::   |....|  .|.:  |.|.
 Worm    30 PHG---CANYGLCTDVT----------------TTLVSSTNISV---IYEYGC--DPDN--CYCL 68

  Fly   600 EG-WGGVTCAENLDDCVGQCRNGA-------TCIDLVNDYRCACASGFKGRDCETDI-DECATSP 655
            || ..|....:.::|   ||.|..       .|...:..|.|:|..||.|.||:::: ..|||||
 Worm    69 EGTTNGTEPCDTIED---QCGNNPCGDPKYFLCTSKIKSYSCSCKPGFTGNDCKSELGSACATSP 130

  Fly   656 CRNGGEC--VD-MVGKFNCICPLGYSGSLCEEAKENCTPSPCLEGHCLNTPE--GYYCHCPPDRA 715
            ||:|..|  || ....:.|||.....|..||.......|.....|:|....:  .:.|.|||...
 Worm   131 CRSGATCESVDNSTAGYKCICKWNQMGENCEYDNFCANPQCQNNGNCSMVVDNANWICSCPPGWQ 195

  Fly   716 GKHCEQLRPLCSQPPCNEGCFANVSLATSATTT----------------------TTTTTTATTT 758
            |:.|| .....:.||..:||:.....:..||||                      |.|....|..
 Worm   196 GRRCE-TPDTVTTPPVWDGCYKYNFQSIGATTTKFSDNQLTVDKCNKYALQQSSDTVTMNYLTLC 259

  Fly   759 RKMAKPSGLP---------------CSGH-----------------GSCEMS----DVGTFCKCH 787
            ......|..|               |.|:                 |:.|:.    |..|||...
 Worm   260 GGFCMVSEGPLCNDTSNWDDDCKKKCGGNNNEFCGVLNKRCIVYEAGTAEVDENACDNSTFCSAD 324

  Fly   788 VGH----------------------TGTFCEHNLNE-CSPNPCRNGGICL-DGDGDFTCECMSGW 828
            :|.                      ||..||:.:.| |:|:||.||...| |....|||.|..|:
 Worm   325 LGQGLCINWQSDFTDGYACICKPLWTGRNCENPVPEACTPSPCLNGTCVLNDQYNKFTCVCDDGF 389

  Fly   829 TGKRCSERATGCYAGQCQNGGTC--MPGAPDKALQPHCRCAPGWTGLFCAEAIDQC-RGQPCHNG 890
            .|.:| :.:..|.:..|..||||  :.....|     |.|...:.|..| |.|::| .|:||:||
 Worm   390 FGDKC-QYSDICTSATCLYGGTCTELNNGDYK-----CDCLLQYFGKNC-EVINRCDYGKPCNNG 447

  Fly   891 ---GTCESGAGWFRCVCAQGFSGPDCRINVNECSPQPCQGGATCIDGIGGYSCICPPGRHGLRCE 952
               .|.:.....:.|.|..|::|.:|...::.|.|.||...:||.....||.|.|..|..|:.|.
 Worm   448 KCASTIDGITTNYTCTCDDGWTGTNCDTMIDFCIPNPCSYNSTCKPKFKGYDCTCITGLTGVNCS 512

  Fly   953 ILLSDPKSACQNASNTISPYTALNRSQNWLDIALTGRTEDDENC----NACVCENGTSRCTNLWC 1013
            .::           :...||.  :.:..|:......: :|..||    |...|..| .:.|:..|
 Worm   513 TII-----------DLCVPYK--DSTGKWIKTPCNSK-DDMANCTKGINTLTCSCG-DKWTDTLC 562

  Fly  1014 GL 1015
            .|
 Worm   563 DL 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser	NP_001287558.1	MNNL	83..161	CDD:284966
		DSL	220..282	CDD:279722
		EGF_CA	350..388	CDD:238011
		EGF_CA	490..526	CDD:238011
		EGF_CA	610..645	CDD:238011	12/41 (29%)
		EGF_CA	647..683	CDD:238011	15/39 (38%)
		EGF_CA	798..833	CDD:238011	15/36 (42%)
		EGF_CA	879..913	CDD:238011	12/37 (32%)
		EGF_CA	916..952	CDD:238011	12/35 (34%)
		VWC_out	<993..1053	CDD:214565	8/27 (30%)
egas-1	NP_001359624.1	deg-1	<595..908	CDD:273309

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000