DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser and AgaP_AGAP005682

DIOPT Version :9

Sequence 1:	NP_001287558.1	Gene:	Ser / 43275	FlyBaseID:	FBgn0004197	Length:	1407	Species:	Drosophila melanogaster
Sequence 2:	XP_315695.4	Gene:	AgaP_AGAP005682 / 1276358	VectorBaseID:	AGAP005682	Length:	452	Species:	Anopheles gambiae

Alignment Length:	346	Identity:	77/346 - (22%)
Similarity:	105/346 - (30%)	Gaps:	110/346 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   674 PLGYSGSLCEEAKENCTPSPCLEGHCLNTPEGYYCHCPPDRAGKHCEQLRPLCSQPPCNEGCF-- 736
            |..|.|:..::...|         |..|.|:.::...||.....|..|..|..|||....|..
Mosquito    90 PYQYPGTTGQQHWGN---------HHGNQPQHHHRETPPQHRRHHRGQAHPSHSQPSSPPGAAGW 145

  Fly   737 ------ANVSLATSATTTTTTTTTATTTRKMAKPSGLPCSGHGSCEMSDVGTFCKCHVGHTGTFC 795
                  ..|..|...|...|.:.|..:.|.....||              ...|..||     :.
Mosquito   146 RRTSGNGGVPAARPVTRMLTRSGTVGSARHNNSTSG--------------KNVCTVHV-----YR 191

  Fly   796 EHNLNECSPNPCRNGGICLDGDGDFTCE------CMSGWTGKRCSERATGCYAGQCQNGGTCMPG 854
            :..:......|||:...|. |...::..      |..||  :..:..|.||:...||.
Mosquito   192 KSVIKTYQGAPCRDPANCY-GLRTYSAPVATREVCCRGW--ETTTTVADGCFKPICQT------- 246

  Fly   855 APDKALQPHCRCAPGWTGLFCAEAIDQCRGQPCHNGGTCESGAGWFRCVCAQGFSGPDCRINVNE 919
                                           ||.|||.|.:..   ||.|..||:|..|.::|||
Mosquito   247 -------------------------------PCRNGGRCTAPD---RCTCPAGFTGKYCELDVNE 277

  Fly   920 CSP-QPCQGGATCIDGIGGYSCICPPGRHGLRCEILLSDPKSACQNASN---------TISPYTA 974
            |.. :||.  .||.:..|.|.|.|..|       .:|...:..|:....         ....|..
Mosquito   278 CKEHKPCD--QTCYNTEGSYYCTCRDG-------FMLQSDRQTCKKIGKLGHRGTPGAMEEKYAT 333

  Fly   975 LNRSQNWLDIALTGRTEDDEN 995
            ||.:.   |:|...|  |.||
Mosquito   334 LNETN---DLATEAR--DMEN 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser	NP_001287558.1	MNNL	83..161	CDD:284966
		DSL	220..282	CDD:279722
		EGF_CA	350..388	CDD:238011
		EGF_CA	490..526	CDD:238011
		EGF_CA	610..645	CDD:238011
		EGF_CA	647..683	CDD:238011	3/8 (38%)
		EGF_CA	798..833	CDD:238011	8/40 (20%)
		EGF_CA	879..913	CDD:238011	12/33 (36%)
		EGF_CA	916..952	CDD:238011	13/36 (36%)
		VWC_out	<993..1053	CDD:214565	2/3 (67%)
AgaP_AGAP005682	XP_315695.4	EGF_CA	<247..272	CDD:238011	12/27 (44%)
AgaP_AGAP005682	XP_315695.4	EGF_CA	274..313	CDD:214542	14/47 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910