DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser and ankle2

DIOPT Version :9

Sequence 1:	NP_001287558.1	Gene:	Ser / 43275	FlyBaseID:	FBgn0004197	Length:	1407	Species:	Drosophila melanogaster
Sequence 2:	XP_004910629.2	Gene:	ankle2 / 100380184	XenbaseID:	XB-GENE-948912	Length:	996	Species:	Xenopus tropicalis

Alignment Length:	179	Identity:	41/179 - (22%)
Similarity:	54/179 - (30%)	Gaps:	51/179 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   674 PLGYSGSLCEEAKENC--TPSPCL--EGHCLNTPEGYYCHCPPDRAGKHCEQLRPLCSQPPCNEG 734
            |..|....|....|.|  .|.|||  ...||..||.  |..||:.           |..||  |.
Frog    45 PCLYPPEPCLYPPEPCLYPPEPCLYPPEPCLYPPEP--CLYPPEP-----------CLYPP--EP 94

  Fly   735 CFANVSLATSATTTTTTTTTATTTRKMAKP---------SGLPCSGHGS---------------- 774
            |.:....||.......:.....:..|:..|         :||.|....|
Frog    95 CLSAPRPATEVQLVAQSMDNILSQLKLLNPDQLREEILKAGLKCGPITSTTRFIFEKKLARVLLE 159

  Fly   775 ---CEMSDVGTFCKCHVGHTGTFCEHNLNECSPNPCRNGGICLDGDGDF 820
               ..:.:..|.|..:.|.:|.....|....:....:|   ||: ||||
Frog   160 QQGVNLEETTTVCDGNAGASGNAGTDNRQHTNYTQKKN---CLE-DGDF 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser	NP_001287558.1	MNNL	83..161	CDD:284966
		DSL	220..282	CDD:279722
		EGF_CA	350..388	CDD:238011
		EGF_CA	490..526	CDD:238011
		EGF_CA	610..645	CDD:238011
		EGF_CA	647..683	CDD:238011	2/8 (25%)
		EGF_CA	798..833	CDD:238011	8/23 (35%)
		EGF_CA	879..913	CDD:238011
		EGF_CA	916..952	CDD:238011
		VWC_out	<993..1053	CDD:214565
ankle2	XP_004910629.2	Cytadhesin_P30	<36..106	CDD:284643	23/75 (31%)
		LEM_ANKL2	118..160	CDD:240591	6/41 (15%)
		Cauli_VI	248..298	CDD:396314
		Ank_2	400..479	CDD:423045
		ANK repeat	400..453	CDD:293786
		ANK repeat	455..488	CDD:293786
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BAFT
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900