Protein Alignment CG5909 and TMPRSS5

DIOPT Version :10

• Sequence 1: NP_651544.1
• Gene: CG5909 / 43274
• FlyBaseID: FBgn0039495
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: NP_110397.2
• Gene: TMPRSS5 / 80975
• HGNCID: 14908
• Length: 457
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 84/276 - (30%)
• Similarity: 126/276 - (45%)
• Gaps: 43/276 - (15%)

  Fly   120 TNCGNKGNP---KVSGGKTARPGDFPW---VALLKYKINDPRPFR--CGGSLISERHILTAAHCI 176
            :.||  ..|   ::.||::..||.:||   |||         .||  ||||:::.|.::|||||:
Human   207 SECG--ARPLASRIVGGQSVAPGRWPWQASVAL---------GFRHTCGGSVLAPRWVVTAAHCM 260

  Fly   177 IDQPEVIAVRLGEHDLESEEDCHYLGGTNRVCIPPYEEYGIEQIRVHPNYVHGKISHDVAIIKLD 241
               ......||....:       :.|..:...:.|::...:|:|..||.|......:|||:::|.
Human   261 ---HSFRLARLSSWRV-------HAGLVSHSAVRPHQGALVERIIPHPLYSAQNHDYDVALLRLQ 315

  Fly   242 RVVKEKSHIKPVCLPIDQKSQELDFDQSFFVAGWGGTEKETV--ATKLQQALITRKSLNECRQ-- 302
            ..:.....:..||||  .|.|........:|:|||.|.....  :..||..::...|...|..
Human   316 TALNFSDTVGAVCLP--AKEQHFPKGSRCWVSGWGHTHPSHTYSSDMLQDTVVPLFSTQLCNSSC 378

  Fly   303 YYNKGEVSDNHICATG--TGIKHTCQGDSGGPVFFKHRFKNTYRVVQYGVVSFGGRLCGQNQPGV 365
            .|: |.::...:|| |  .|....||||||||:....  .:|:|:|  ||||:|......|.|||
Human   379 VYS-GALTPRMLCA-GYLDGRADACQGDSGGPLVCPD--GDTWRLV--GVVSWGRGCAEPNHPGV 437

  Fly   366 FASVIDMLPWITQNLQ 381
            :|.|.:.|.||....|
Human   438 YAKVAEFLDWIHDTAQ 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5909	NP_651544.1	CLIP	25..82	CDD:197829
		Tryp_SPc	132..379	CDD:238113	80/257 (31%)
TMPRSS5	NP_110397.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		SRCR_2	116..213	CDD:464747	2/7 (29%)
		Tryp_SPc	217..448	CDD:214473	78/257 (30%)