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Protein Alignment CG5909 and TMPRSS4

DIOPT Version :10

Sequence 1:	NP_651544.1	Gene:	CG5909 / 43274	FlyBaseID:	FBgn0039495	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	XP_005271670.1	Gene:	TMPRSS4 / 56649	HGNCID:	11878	Length:	494	Species:	Homo sapiens

Alignment Length:	269	Identity:	80/269 - (29%)
Similarity:	122/269 - (45%)	Gaps:	49/269 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 CGNK-GNPKVSGGKTARPGDFPWVALLKYKINDPRPFRCGGSLISERHILTAAHCIIDQPEVI-- 183
            ||.. ..|:|.|.:.|....:||...::|    .:...||||::....:||||||.....:|.
Human   196 CGKSLKTPRVVGVEEASVDSWPWQVSIQY----DKQHVCGGSILDPHWVLTAAHCFRKHTDVFNW 256

  Fly   184 AVRLGEHDLESEEDCHYLGGTNRVCIPPYEEYGIEQIRVHPNYVHGKISHDVAIIKLDRVVKEKS 248
            .||.|...|.|              .|......|..|..:|.|..   .:|:|::||...:....
Human   257 KVRAGSDKLGS--------------FPSLAVAKIIIIEFNPMYPK---DNDIALMKLQFPLTFSG 304

  Fly   249 HIKPVCLPIDQKSQELDFDQSFFVAGWGGTEKE--TVATKLQQALI-----TRKSLNECRQYYNK 306
            .::|:|||.  ..:||......::.|||.|::.  .::..|.||.:     ||.:.::..|
Human   305 TVRPICLPF--FDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQ---- 363

  Fly   307 GEVSDNHICATGTGIKH----TCQGDSGGPVFFKHRFKNTYRVVQYGVVSFGGRLCGQNQPGVFA 367
            |||::..:||   ||..    |||||||||:.::   .:.:.||  |:||:|....|.:.|||:.
Human   364 GEVTEKMMCA---GIPEGGVDTCQGDSGGPLMYQ---SDQWHVV--GIVSWGYGCGGPSTPGVYT 420

  Fly   368 SVIDMLPWI 376
            .|...|.||
Human   421 KVSAYLNWI 429

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.