DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5909 and f10

DIOPT Version :9

Sequence 1:	NP_651544.1	Gene:	CG5909 / 43274	FlyBaseID:	FBgn0039495	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_001015728.1	Gene:	f10 / 548445	XenbaseID:	XB-GENE-971433	Length:	464	Species:	Xenopus tropicalis

Alignment Length:	364	Identity:	105/364 - (28%)
Similarity:	170/364 - (46%)	Gaps:	61/364 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 GQCIRYQECPFVQK----------ILGIYGRN-IPRKIHNQISEMQCRSTTNTRDFHLCCPNEAP 86
            |:|.:|  |..|.:          |||..|:: :|.:.::.......|....|: .|     |..
Frog   133 GECDQY--CKAVDRDVVCSCTNGYILGENGKSCLPTEKYSCGRRHMKRERRETK-LH-----END 189

  Fly    87 PQSNQESQRKVVRSEGGNLNRYDRQGLQLLNSVTNCGNKGNPKVSGGKTARPGDFPWVALLKYKI 151
            .:::.:||.:|..::.|.|...:..|:.:||.     |..|.::.||:....|:.||.|||   :
Frog   190 KKNHTDSQNEVKMNQTGTLPERNVTGINILNP-----NDPNVRIVGGRECSQGECPWQALL---V 246

  Fly   152 NDPRPFRCGGSLISERHILTAAHCIIDQPEVIAVRLGEHDLESEEDCHYLGGTNRVCIPPYEEYG 216
            :|.....|||:::|...||||||| ::|.:...|.:||.:.:..|      ||..:       :.
Frog   247 SDEDEGFCGGTILSREFILTAAHC-MNQTKYFKVVVGELNTKISE------GTESI-------HK 297

  Fly   217 IEQIRVHPNYVHGKISHDVAIIKLDRVVKEKSHIKPVCLPIDQ-KSQELDFDQSFFVAGWG---- 276
            :|:|.:||.:|.....:|:|:|||...:....:|.|.|:|..: ..|.|..:....|:|:|
Frog   298 VEKIIMHPRFVKSTYDYDIAVIKLKEAINFTENIIPACIPDPEFADQVLMNEPDAMVSGFGRIHE 362

  Fly   277 -GTEKETVATKLQQALITRKSLNECRQYYNKGEVSDNHICA-TGTGIKHTCQGDSGGPVFFKH-- 337
             |.:..|: ..||...|.|.|..|...:    .:::|..|| ..|.:|..||||||||    |
Frog   363 RGRQASTL-QMLQVPYIKRHSCKESSTF----AITENMFCAGFDTEVKDACQGDSGGP----HVT 418

  Fly   338 RFKNTYRVVQYGVVSFGGRLCGQNQPGVFASVIDMLPWI 376
            .||.||.|.  |:||:|.....:.:.||:..|..:..|:
Frog   419 PFKGTYFVT--GIVSWGEGCARKGKFGVYTKVSKLHRWL 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5909	NP_651544.1	CLIP	25..82	CDD:197829	13/59 (22%)
		Tryp_SPc	129..376	CDD:214473	80/255 (31%)
		Tryp_SPc	132..379	CDD:238113	81/254 (32%)
f10	NP_001015728.1	GLA	22..84	CDD:214503
		EGF_CA	85..121	CDD:238011
		FXa_inhibition	128..163	CDD:373209	9/31 (29%)
		Tryp_SPc	228..456	CDD:238113	81/256 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920