Protein Alignment CG5909 and Tmprss2

DIOPT Version :10

• Sequence 1: NP_651544.1
• Gene: CG5909 / 43274
• FlyBaseID: FBgn0039495
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: NP_056590.2
• Gene: Tmprss2 / 50528
• MGIID: 1354381
• Length: 490
• Species: Mus musculus
• Alignment Length: 406
• Identity: 106/406 - (26%)
• Similarity: 173/406 - (42%)
• Gaps: 75/406 - (18%)

  Fly    23 SSCVTPAQ---AAGQCIR-------YQECPFVQ---KILGIYGRNIPRKIHN------------- 61
            |:|.|...   ::|.||.       ...||..:   :.:.:||::...::::
Mouse   110 SNCSTSEMECGSSGTCISSSLWCDGVAHCPNGEDENRCVRLYGQSFILQVYSSQRKAWYPVCQDD 174

  Fly    62 ---QISEMQCRSTTNTRDFHLCCPNEAPPQSNQESQRKVVRSEGGNLNRY------DRQGLQLLN 117
               ......|:......:|:  .....|.||...|..| :....||::.|      |....:::.
Mouse   175 WSESYGRAACKDMGYKNNFY--SSQGIPDQSGATSFMK-LNVSSGNVDLYKKLYHSDSCSSRMVV 236

  Fly   118 SV--TNCG---NKGNPKVSGGKTARPGDFPW-VALLKYKINDPRPFRCGGSLISERHILTAAHCI 176
            |:  ..||   .|...::.||..|.|||:|| |:|....::     .||||:|:...|:|||||:
Mouse   237 SLRCIECGVRSVKRQSRIVGGLNASPGDWPWQVSLHVQGVH-----VCGGSIITPEWIVTAAHCV 296

  Fly   177 IDQPEVIAVRLGEHDLESEEDCHYLGGTNRVCIPPY-EEYGIEQIRVHPNYVHGKISHDVAIIKL 240
                        |..|.|........|..|..:..| ..:.:|::..||||.....::|:|::||
Mouse   297 ------------EEPLSSPRYWTAFAGILRQSLMFYGSRHQVEKVISHPNYDSKTKNNDIALMKL 349

  Fly   241 DRVVKEKSHIKPVCLPIDQKSQELDFDQSFFVAGWGGT-EKETVATKLQQALITRKSLNECR-QY 303
            ...:.....:||||||  .....||.||..:::|||.| ||...:..|..|::.....::|. :|
Mouse   350 QTPLAFNDLVKPVCLP--NPGMMLDLDQECWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKY 412

  Fly   304 YNKGEVSDNHICATG--TGIKHTCQGDSGGPVFFKHRFKN-TYRVVQYGVVSFGGRLCGQNQPGV 365
            .....::...||| |  .|...:||||||||:.   ..|| .:.::  |..|:|.......:|||
Mouse   413 IYNNLITPAMICA-GFLQGSVDSCQGDSGGPLV---TLKNGIWWLI--GDTSWGSGCAKALRPGV 471

  Fly   366 FASVIDMLPWITQNLQ 381
            :.:|.....||.|.::
Mouse   472 YGNVTVFTDWIYQQMR 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5909	NP_651544.1	CLIP	25..82	CDD:197829	11/85 (13%)
		Tryp_SPc	132..379	CDD:238113	80/253 (32%)
Tmprss2	NP_056590.2	LDLa	112..147	CDD:238060	7/34 (21%)
		SRCR_2	152..247	CDD:464747	15/97 (15%)
		Tryp_SPc	254..485	CDD:238113	80/255 (31%)