DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5909 and F10

DIOPT Version :9

Sequence 1:	NP_651544.1	Gene:	CG5909 / 43274	FlyBaseID:	FBgn0039495	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_058839.1	Gene:	F10 / 29243	RGDID:	61850	Length:	482	Species:	Rattus norvegicus

Alignment Length:	405	Identity:	107/405 - (26%)
Similarity:	175/405 - (43%)	Gaps:	82/405 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 TPAQAAGQC---IRYQECPFVQKILGIYGRN---IPRK---IHNQISEMQCRSTTNT------RD 76
            :|.|..|:|   :....|...:   |..|:|   ..||   :.|...:..||...|:      :.
  Rat    93 SPCQNQGECRDGLGSYTCTCTE---GFEGKNCELFVRKLCSLDNGDCDQFCREEQNSVVCSCAKG 154

  Fly    77 FHL-----CCPNEAPPQSNQESQRKVVRSEGGNLNRY--DRQGL--------------QLLNSVT 120
            :.|     .|.:.||....:.::.:..||...|.:..  |.:.|              :|||.
  Rat   155 YFLGNDGKSCLSTAPFPCGKTNKGRAKRSVALNTSNSEPDPEDLMPDADILYPTESPSELLNL-- 217

  Fly   121 NCGNKGNP--------KVSGGKTARPGDFPWVALLKYKINDPRPFRCGGSLISERHILTAAHCII 177
               ||..|        ::.||:..:.|:.||.||| :...:...| |||::::|.:||||||| :
  Rat   218 ---NKTEPEANSDDVIRIVGGQECKRGECPWQALL-FSDEETDGF-CGGTILNEFYILTAAHC-L 276

  Fly   178 DQPEVIAVRLGEHDLESEEDCHYLGGTNRVCIPPYEEYGIEQIRVHPNYVHGKISHDVAIIKLDR 242
            .|.:...||:|:.:.|.|:     ||.        ..:.::.|..|..:.......|:|:::|..
  Rat   277 HQAKRFKVRVGDLNTEQED-----GGE--------MVHEVDMIIKHNKFQRDTYDFDIAMLRLKT 328

  Fly   243 VVKEKSHIKPVCLP-IDQKSQELDFDQSFFVAGWGGT-EKETVATKLQQALITRKSLNECRQYYN 305
            .:..:.::.|.||| .|.....|...::..|:|:|.| ||...:..|:...:.....|.|| ...
  Rat   329 PITFRENVAPACLPQKDWAEATLMTQKTGIVSGFGRTHEKGRQSKVLKMMEVPYVDRNTCR-LST 392

  Fly   306 KGEVSDNHICATGTGIKH--TCQGDSGGPVFFKH--RFKNTYRVVQYGVVSFGGRLCGQNQPGVF 366
            ...::.|..|| |...|.  .||||||||    |  |||:||.|.  |:||:|.....:.:.|::
  Rat   393 SFSITQNMFCA-GYDAKQEDACQGDSGGP----HVTRFKDTYFVT--GIVSWGEGCARKGKYGIY 450

  Fly   367 ASVIDMLPWITQNLQ 381
            ..|...|.||.::::
  Rat   451 TKVTAFLKWIDRSMK 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5909	NP_651544.1	CLIP	25..82	CDD:197829	15/74 (20%)
		Tryp_SPc	129..376	CDD:214473	76/252 (30%)
		Tryp_SPc	132..379	CDD:238113	78/252 (31%)
F10	NP_058839.1	GLA	23..84	CDD:214503
		EGF_CA	86..122	CDD:238011	8/31 (26%)
		FXa_inhibition	129..164	CDD:405372	5/34 (15%)
		Tryp_SPc	232..462	CDD:238113	78/253 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920