DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5909 and f7i

DIOPT Version :9

Sequence 1:	NP_651544.1	Gene:	CG5909 / 43274	FlyBaseID:	FBgn0039495	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_775335.1	Gene:	f7i / 282671	ZFINID:	ZDB-GENE-021206-10	Length:	443	Species:	Danio rerio

Alignment Length:	464	Identity:	102/464 - (21%)
Similarity:	163/464 - (35%)	Gaps:	147/464 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLLCILPQLVISQSSCV----TPAQAAGQCIRYQECPFVQKILGIYGRNIPRKIHNQISEMQ--- 67
            :|||:   |.:..:|.|    ..|.|..|..|.....|:::   :...|:.|:...:|.:.:
Zfish     8 VLLCV---LTLRSTSAVFLSKDEASALLQRFRRANSGFLEE---MKAGNLERECVEEICDYEEAR 66

  Fly    68 --CRSTTNTRDFHLCCPNEAPPQSNQESQRKVVRSEG---------------GNLNRYDRQGLQ- 114
              ......|:.|.|...|:.|..:|.      .|:.|               |...:|..:||:
Zfish    67 EVFEDDDRTKQFWLSYSNKEPCLTNP------CRNNGTCVYLADSYYCLCSEGYEGKYCEKGLEE 125

  Fly   115 -------------------------------LLNSVTNC--------------GNKGNPKVSGGK 134
                                           |.:..|:|              .|....:..||.
Zfish   126 TLKCQYVNGGCEQFCDGSGARRSCSCAEGYALADDGTSCVSQVDYPCGKIPVQKNTSQNQFLGGI 190

  Fly   135 TARPGDFPWVALLKYKINDPRPFRCGGSLISERHILTAAHCIIDQ-PEVIAVRLGEHDLE----S 194
            ....|..||..|:.|.....    |||:|:....::|||||:..: ...:....|||||:    |
Zfish   191 HCPRGHCPWQVLIDYNGESV----CGGALLEGPWLITAAHCVHQKDTRFLKAVTGEHDLDVLDGS 251

  Fly   195 EEDCHYLGGTNRVCIPPYEEYGIEQIRVHPNYVHGKISHDVAIIKLDRVVKEKSHIKPVCLPIDQ 259
            ||              |||   :..:.:||||....:..|:|:::|...|:...:..|:|||..|
Zfish   252 EE--------------PYE---VSAVFIHPNYDPETLDSDLALLRLRVPVQRSLYAVPICLPTPQ 299

  Fly   260 KSQ-ELDFDQSFFVAGWGGTE-----------KETVATKLQQALITRKSLNECRQYYNKGEVSDN 312
            .:: ||...:...::|||...           |...:..||:..:......:|    .....:.|
Zfish   300 LARSELWAARFHTLSGWGTRTAGHNLRREKGLKGPASGTLQRLAVPLLPAAQC----GNANTTAN 360

  Fly   313 HICATGTGIKH-TCQGDSGGPVFFKHRFKNTYRVVQYGVVSF------GGRLCGQNQPG---VFA 367
            ..||..|...| :|:|..|.|:           |.:||..||      .||.||  .||   ::.
Zfish   361 MFCAGYTEGDHASCRGHDGSPL-----------VTRYGETSFLTGVVSWGRGCG--PPGYYWIYT 412

  Fly   368 SVIDMLPWI 376
            .|.:.|.|:
Zfish   413 KVENFLIWM 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5909	NP_651544.1	CLIP	25..82	CDD:197829	12/65 (18%)
		Tryp_SPc	129..376	CDD:214473	71/273 (26%)
		Tryp_SPc	132..379	CDD:238113	72/272 (26%)
f7i	NP_775335.1	GLA	20..82	CDD:214503	12/64 (19%)
		EGF_CA	<91..120	CDD:238011	5/34 (15%)
		FXa_inhibition	129..164	CDD:291342	2/34 (6%)
		Tryp_SPc	188..420	CDD:214473	71/269 (26%)
		Tryp_SPc	188..420	CDD:238113	71/269 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910