DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5909 and CG33225

DIOPT Version :9

Sequence 1:	NP_651544.1	Gene:	CG5909 / 43274	FlyBaseID:	FBgn0039495	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_001286682.1	Gene:	CG33225 / 2768860	FlyBaseID:	FBgn0053225	Length:	307	Species:	Drosophila melanogaster

Alignment Length:	293	Identity:	83/293 - (28%)
Similarity:	138/293 - (47%)	Gaps:	55/293 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 GLQLLNS--VTN-CGNKGNP----KVSGGKTARPGDFPWVALLKYKINDPRPFRCGGSLISERHI 169
            |.:|.:|  :|| ||...:|    :|.||..|.....||:.::   :.:...| |.||||:...:
  Fly    32 GARLGSSTLLTNDCGTTRHPSRIRRVVGGNDADRFANPWMVMV---LGENNVF-CSGSLITRLFV 92

  Fly   170 LTAAHCIIDQPEVIAVRLGEHDLESEEDCHYLGGTNRVCIPPYEEYGIEQIRVHPNYVHGKI--- 231
            ||:|.|::..|:  .|.|||:|    .:|     |:..|....:...|:|     ..:||:.
  Fly    93 LTSASCLLSLPK--QVILGEYD----RNC-----TSADCTSIRQVIDIDQ-----KIIHGQFGLE 141

  Fly   232 ---SHDVAIIKLDRVVKEKSHIKPVCLPID-QKSQELDFDQSFFVAGWGGTEKETVATKLQQALI 292
               .:|:|:::|.:.|....:::|:||.:| |..:.:   |.|...|||.||....:|.||..
  Fly   142 TVKKYDIALLRLAKKVSISDYVRPICLSVDRQVGRSV---QHFTATGWGTTEWNEPSTILQTV-- 201

  Fly   293 TRKSLNECRQYYNKGEVSDN----HICATGTGIKHTCQGDSGGPVFF------KHRFKNTYRVVQ 347
               :|::..:.|.||.:..|    .:|..|.. |.||.||:|||:..      ..::.|..|...
  Fly   202 ---TLSKINRKYCKGRLRQNIDASQLCVGGPR-KDTCSGDAGGPLSLTLKIDGDGKWNNKSRAFL 262

  Fly   348 YGVVSFGGRLCGQNQPGVFASVIDMLPWITQNL 380
            .|:||:|...|  :..||:.:|...:.||.:.:
  Fly   263 IGIVSYGSSSC--SGIGVYTNVEHYMDWIVRTI 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5909	NP_651544.1	CLIP	25..82	CDD:197829
		Tryp_SPc	129..376	CDD:214473	73/263 (28%)
		Tryp_SPc	132..379	CDD:238113	74/263 (28%)
CG33225	NP_001286682.1	Tryp_SPc	56..289	CDD:214473	73/263 (28%)
CG33225	NP_001286682.1	Tryp_SPc	57..292	CDD:238113	75/265 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	1	0.900	-	-		E33208_3BQ4K
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810