Protein Alignment CG5909 and KLK5

DIOPT Version :10

• Sequence 1: NP_651544.1
• Gene: CG5909 / 43274
• FlyBaseID: FBgn0039495
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 85/304 - (27%)
• Similarity: 126/304 - (41%)
• Gaps: 78/304 - (25%)

  Fly   115 LLNSVTNCGNKGNPKVSG---------GKTARPGDF---------------PWVALLKYKINDPR 155
            |.|:..:|.:..|...||         |:.||..|.               ||.|.|..:   |.
Human    28 LANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLR---PN 89

  Fly   156 PFRCGGSLISERHILTAAHCIIDQPEVIAVRLGEHDLESEEDCHYLGGTNRVCIPPYEE-----Y 215
            ...||..|:..:.:||||||   :.:|..||||.:.|.                |.||.     .
Human    90 QLYCGAVLVHPQWLLTAAHC---RKKVFRVRLGHYSLS----------------PVYESGQQMFQ 135

  Fly   216 GIEQIRVHPNYVHGKISHDVAIIKLDRVVKEKSHIKPV-----CLPIDQKSQELDFDQSFFVAGW 275
            |::.| .||.|.|...|:|:.:|||:|.::....::|:     |.....|.         .|:||
Human   136 GVKSI-PHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKC---------LVSGW 190

  Fly   276 GGTEKETV-ATKLQQAL-ITRKSLNECRQYYNKGEVSDNHICATGTGIKHTCQGDSGGPVFFKHR 338
            |.|:...| ..|:.|.| |:..|...|...|.: ::.|...||.....:.:|||||||||.....
Human   191 GTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPR-QIDDTMFCAGDKAGRDSCQGDSGGPVVCNGS 254

  Fly   339 FKNTYRVVQYGVVSFGGRLCGQ-NQPGVFASVIDMLPWITQNLQ 381
            .:        |:||:|...|.: |:|||:.::.....||.:.:|
Human   255 LQ--------GLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5909	NP_651544.1	CLIP	25..82	CDD:197829
		Tryp_SPc	132..379	CDD:238113	79/283 (28%)
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		7/30 (23%)
		Tryp_SPc	66..285	CDD:214473	72/259 (28%)