DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5909 and Klk1b3

DIOPT Version :9

Sequence 1:	NP_651544.1	Gene:	CG5909 / 43274	FlyBaseID:	FBgn0039495	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_113711.1	Gene:	Klk1b3 / 24594	RGDID:	3175	Length:	265	Species:	Rattus norvegicus

Alignment Length:	266	Identity:	71/266 - (26%)
Similarity:	113/266 - (42%)	Gaps:	50/266 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 KVSGGKTARPGDFPWVALLKYKINDPRPFRCGGSLISERHILTAAHCIIDQPEVIAVRLGEHDLE 193
            :|.||........||...:.|.    ..:.|||.||....::|||||..|..:   |.||.::|.
  Rat    28 RVVGGYNCEMNSQPWQVAVYYF----GEYLCGGVLIDPSWVITAAHCATDNYQ---VWLGRNNLY 85

  Fly   194 SEEDCHYLGGTNRVCIPPYEEYG-IEQIRVHPNYVHGKI-----------SHDVAIIKLDRVVKE 246
            .:|              |:.::. :.|...||.:....|           |:|:.::.|.:....
  Rat    86 EDE--------------PFAQHRLVSQSFPHPGFNQDLIWNHTRQPGDDYSNDLMLLHLSQPADI 136

  Fly   247 KSHIKPVCLPIDQKSQELDFDQSFFVAGWGGTEKE--TVATKLQQALITRKSLNECRQYYNKGEV 309
            ...:|.:.|||    :|.....:...:|||....:  .::..||...|...|..:|.:.: |.||
  Rat   137 TDGVKVIDLPI----EEPKVGSTCLASGWGSITPDGLELSDDLQCVNIDLLSNEKCVEAH-KEEV 196

  Fly   310 SDNHICA-TGTGIKHTCQGDSGGPVFFKHRFKNTYRVVQYGVVSFGGRLCGQ-NQPGVFASVIDM 372
            :|..:|| ...|.|.||:||||||:....        |..|:.|:|...||: .:||::..:|..
  Rat   197 TDLMLCAGEMDGGKDTCKGDSGGPLICNG--------VLQGITSWGFNPCGEPKKPGIYTKLIKF 253

  Fly   373 LPWITQ 378
            .|||.:
  Rat   254 TPWIKE 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5909	NP_651544.1	CLIP	25..82	CDD:197829
		Tryp_SPc	129..376	CDD:214473	69/262 (26%)
		Tryp_SPc	132..379	CDD:238113	70/263 (27%)
Klk1b3	NP_113711.1	Tryp_SPc	28..257	CDD:214473	69/262 (26%)
Klk1b3	NP_113711.1	Tryp_SPc	29..260	CDD:238113	71/265 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000