DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5909 and svh-1

DIOPT Version :9

Sequence 1:	NP_651544.1	Gene:	CG5909 / 43274	FlyBaseID:	FBgn0039495	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_501379.2	Gene:	svh-1 / 182375	WormBaseID:	WBGene00006620	Length:	951	Species:	Caenorhabditis elegans

Alignment Length:	348	Identity:	93/348 - (26%)
Similarity:	144/348 - (41%)	Gaps:	91/348 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 HNQISEMQC---RSTTNTRDFHLCCPNEAPPQSNQESQRKVVRSEGGNLNRYDRQGLQLLNSVTN 121
            :|...::.|   ||::.||...:.|                 .|:.|            ::|.:.
Worm   657 YNVNCDVDCSIRRSSSCTRHARISC-----------------ISQNG------------MSSASQ 692

  Fly   122 CG------------NKGNPKVSGGKTARPGDFPWVALLKYKINDPRPFRCGGSLISERHILTAAH 174
            ||            .....:|.||....||.|||.|.|:.|..  :...||.|::.:.|::||||
Worm   693 CGLRYVEVNARDAAKSRIARVVGGFETVPGAFPWTAALRNKAT--KAHHCGASILDKTHLITAAH 755

  Fly   175 CIIDQPEVIA--VRLGEHD---LESEEDCHYLGGTNRVCIPPYEEYGIEQIRVHPNYVHGKISHD 234
            |..:...|.:  |.:|:.|   .:..|...||                ::|..:|.| ....|||
Worm   756 CFEEDERVSSYEVVVGDWDNNQTDGNEQIFYL----------------QRIHFYPLY-KDIFSHD 803

  Fly   235 VAIIKLDRV-VKEKSHIKPVCLPIDQKSQELDF----DQSFFVAGWGGTEKETVATKLQQALITR 294
            :||:::... ::...:.:|:|||      ..||    .:...|:|||..... .|.:||.|||..
Worm   804 IAILEIPYPGIEFNEYAQPICLP------SKDFVYTPGRQCVVSGWGSMGLR-YAERLQAALIPI 861

  Fly   295 KSLNEC---RQYYNKGEVSDNHICA--TGTGIKHTCQGDSGGPVFFKHRFKNTYRVVQYGVVSFG 354
            .:..:|   .|.|:  .:|.:..||  ...|| .:|||||||| |...|....:  |..||:|:|
Worm   862 INRFDCVNSSQIYS--SMSRSAFCAGYLEGGI-DSCQGDSGGP-FACRREDGAF--VLAGVISWG 920

  Fly   355 GRLCGQNQPGVFASVIDMLPWIT 377
            .....:.|||::..|...|.||:
Worm   921 DGCAQKKQPGIYTMVAPYLSWIS 943

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5909	NP_651544.1	CLIP	25..82	CDD:197829	6/24 (25%)
		Tryp_SPc	129..376	CDD:214473	79/261 (30%)
		Tryp_SPc	132..379	CDD:238113	80/261 (31%)
svh-1	NP_501379.2	KR	227..306	CDD:214527
		LDLa	320..355	CDD:238060
		PAN_AP_HGF	373..434	CDD:238532
		LDLa	558..590	CDD:197566
		SRCR_2	599..681	CDD:382996	6/23 (26%)
		Tryp_SPc	713..945	CDD:238113	81/263 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910