DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5909 and try-1

DIOPT Version :9

Sequence 1:	NP_651544.1	Gene:	CG5909 / 43274	FlyBaseID:	FBgn0039495	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_494910.2	Gene:	try-1 / 173856	WormBaseID:	WBGene00006619	Length:	293	Species:	Caenorhabditis elegans

Alignment Length:	263	Identity:	79/263 - (30%)
Similarity:	117/263 - (44%)	Gaps:	42/263 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 KVSGGKTARPGDFPWVALLKYKINDPRPFRCGGSLISERHILTAAHCIID--QPEVIAVRLGEHD 191
            ::.||..:.|..:||...|..::..   .|||||||....:||||||...  :|...:||:|.|.
Worm    57 RLIGGSESSPHSWPWTVQLLSRLGH---HRCGGSLIDPNFVLTAAHCFAKDRRPTSYSVRVGGHR 118

  Fly   192 LESEEDCHYLGGTNRVCIPPYEEYGIEQIRVHPNYVHG-KISHDVAIIKLDRVVKEKSHIKPVCL 255
            ..|       |..:||          ..:.:||.|..| ..|:|.||:::...|...:..:|:||
Worm   119 SGS-------GSPHRV----------TAVSIHPWYNIGFPSSYDFAIMRIHPPVNTSTTARPICL 166

  Fly   256 PIDQKSQELDFDQSFFVAGWGGT-EKETV-ATKLQQALITRKSLNECRQYYNK-GEVS-DNHICA 316
            |    |.....::...|.|||.| |..:: |..|::..:...|...|....|. |.:. .:.:||
Worm   167 P----SLPAVENRLCVVTGWGSTIEGSSLSAPTLREIHVPLLSTLFCSSLPNYIGRIHLPSMLCA 227

  Fly   317 -TGTGIKHTCQGDSGGPVFFKH--RFKNTYRVVQYGVVSFGGRLCGQNQPGVFASVIDMLPWITQ 378
             ...|...:||||||||:....  .::.|      ||||:|........|||:.:|.....||
Worm   228 GYSYGKIDSCQGDSGGPLMCARDGHWELT------GVVSWGIGCARPGMPGVYGNVHSASTWI-- 284

  Fly   379 NLQ 381
            ||:
Worm   285 NLE 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5909	NP_651544.1	CLIP	25..82	CDD:197829
		Tryp_SPc	129..376	CDD:214473	75/256 (29%)
		Tryp_SPc	132..379	CDD:238113	77/256 (30%)
try-1	NP_494910.2	Tryp_SPc	59..285	CDD:238113	77/257 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910