DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5909 and CG43335

DIOPT Version :9

Sequence 1:	NP_651544.1	Gene:	CG5909 / 43274	FlyBaseID:	FBgn0039495	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_001247121.1	Gene:	CG43335 / 12798413	FlyBaseID:	FBgn0263040	Length:	281	Species:	Drosophila melanogaster

Alignment Length:	262	Identity:	83/262 - (31%)
Similarity:	125/262 - (47%)	Gaps:	23/262 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 NCGNKGNP-----KVSGGKTARPGDFPWVALLKYKINDPRPFRCGGSLISERHILTAAHCIIDQP 180
            |||.:..|     ::.||..|.....||:|   |..|:...| |.|:||:.:.:|||||| |:..
  Fly    28 NCGIRTMPSFHRTRIIGGSDAEITSHPWMA---YLYNEFHYF-CAGTLITNQFVLTAAHC-IEAS 87

  Fly   181 EVIAVRLGEHDLESEEDCHYLGGTNRVCIPPYEEYGIEQIRVHPNYVHGKISHDVAIIKLDRVVK 245
            :.:.||||...|...:        ..:|....|:|.:.....|..:....:.:|:|:|:|.|.||
  Fly    88 KNLTVRLGGSGLTRSD--------GSMCQITAEDYSVSMAIKHKYFTPSIMLNDIAMIRLARTVK 144

  Fly   246 EKSHIKPVCLPIDQKSQELDFD-QSFFVAGWGGTEKETVATKLQQALITRKSLNECRQYYNKGEV 309
            ...||:|:|:.:|...:.|..| .:....|||..:|......||:|.||..:.|.|.:.|:.. :
  Fly   145 FYDHIRPICIILDPAVRLLLEDGMTLMATGWGLADKRMHPHLLQEAPITVMNRNVCSKLYDVA-I 208

  Fly   310 SDNHICATGTGIKHTCQGDSGGPVFFKHRFKNTYRVVQYGVVSFGGRLCGQNQPGVFASVIDMLP 374
            :...||| |....:||.||||||:.....:....|.||||:.|||...|  ..|.::..:.....
  Fly   209 TQGQICA-GDKETNTCLGDSGGPLGGVVNYYGDLRFVQYGITSFGDIEC--RSPSIYTDLSTYSG 270

  Fly   375 WI 376
            ||
  Fly   271 WI 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5909	NP_651544.1	CLIP	25..82	CDD:197829
		Tryp_SPc	129..376	CDD:214473	77/247 (31%)
		Tryp_SPc	132..379	CDD:238113	79/246 (32%)
CG43335	NP_001247121.1	Tryp_SPc	41..272	CDD:214473	77/247 (31%)
CG43335	NP_001247121.1	Tryp_SPc	42..275	CDD:238113	79/248 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	1	0.900	-	-		E33208_3BQ4K
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25778
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.820