DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment grass and Prss8

DIOPT Version :9

Sequence 1:	NP_651543.1	Gene:	grass / 43273	FlyBaseID:	FBgn0039494	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_579929.1	Gene:	Prss8 / 76560	MGIID:	1923810	Length:	339	Species:	Mus musculus

Alignment Length:	278	Identity:	88/278 - (31%)
Similarity:	127/278 - (45%)	Gaps:	53/278 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 CGNFLSQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCV---HGLQNDL 172
            ||..:..|::.|...|....||...:.|    :...:|||:::|.:::::||||.   |  ..:.
Mouse    37 CGAVIQPRITGGGSAKPGQWPWQVSITY----DGNHVCGGSLVSNKWVVSAAHCFPREH--SREA 95

  Fly   173 YEIRLGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVPFQK 237
            ||::||.|::.:..:           ..||:. :.:.:.|..|.......||||::|:..|.|.:
Mouse    96 YEVKLGAHQLDSYSN-----------DTVVHT-VAQIITHSSYREEGSQGDIALIRLSSPVTFSR 148

  Fly   238 HIKPICLPITDELKEKAEQISTYFVTGWGTTENGSSSDV---LLQANVPLQPRSACSQAYR-RAV 298
            :|:|||||..:.........:   |||||......|...   |.|..|||..|..||..|. .||
Mouse   149 YIRPICLPAANASFPNGLHCT---VTGWGHVAPSVSLQTPRPLQQLEVPLISRETCSCLYNINAV 210

  Fly   299 P-------LSQLCVG---GGDLQDSCKGDSGGPLQAPAQ---YLGEYAPKMVEFGIVSQGVVTCG 350
            |       ...||.|   ||  :|:|:|||||||..|.:   ||.         ||||.| ..||
Mouse   211 PEEPHTIQQDMLCAGYVKGG--KDACQGDSGGPLSCPMEGIWYLA---------GIVSWG-DACG 263

  Fly   351 QISLPGLYTNVGEYVQWI 368
            ..:.||:||....|..||
Mouse   264 APNRPGVYTLTSTYASWI 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
grass	NP_651543.1	CLIP	32..90	CDD:197829
grass	NP_651543.1	Tryp_SPc	121..371	CDD:238113	85/268 (32%)
Prss8	NP_579929.1	Tryp_SPc	45..284	CDD:238113	85/270 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910