DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment grass and Prss3

DIOPT Version :9

Sequence 1:	NP_651543.1	Gene:	grass / 43273	FlyBaseID:	FBgn0039494	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_035775.1	Gene:	Prss3 / 22073	MGIID:	102758	Length:	246	Species:	Mus musculus

Alignment Length:	275	Identity:	84/275 - (30%)
Similarity:	128/275 - (46%)	Gaps:	53/275 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 DENFDCGNFLSQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQN 170
            |::...|.:..|..|..|:|.|:|              ....|||::|:::::::||||    ..
Mouse    20 DDDKIVGGYTCQENSVPYQVSLNS--------------GYHFCGGSLINDQWVVSAAHC----YK 66

  Fly   171 DLYEIRLGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVPF 235
            ...::|||||.|:..|...|          .||..  |.:.|..::.:.:.:||.||||:..|..
Mouse    67 TRIQVRLGEHNINVLEGNEQ----------FVNAA--KIIKHPNFNRKTLNNDIMLLKLSSPVTL 119

  Fly   236 QKHIKPICLPITDELKEKAEQISTYFVTGWGTTEN-GSSSDVLLQA-NVPLQPRSACSQAYRRAV 298
            ...:..:.||     ...|...:...::|||.|.: |.|...|||. :.||.|::.|..:|...:
Mouse   120 NARVATVALP-----SSCAPAGTQCLISGWGNTLSFGVSEPDLLQCLDAPLLPQADCEASYPGKI 179

  Fly   299 PLSQLCVG---GGDLQDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVTCGQISLPGLYTN 360
            ..:.:|.|   ||  :|||:||||||:....:..          ||||.| ..|.....||:||.
Mouse   180 TGNMVCAGFLEGG--KDSCQGDSGGPVVCNRELQ----------GIVSWG-YGCALPDNPGVYTK 231

  Fly   361 VGEYVQWITDTMASN 375
            |..||.||.||:|:|
Mouse   232 VCNYVDWIQDTIAAN 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
grass	NP_651543.1	CLIP	32..90	CDD:197829
grass	NP_651543.1	Tryp_SPc	121..371	CDD:238113	76/254 (30%)
Prss3	NP_035775.1	Tryp_SPc	23..239	CDD:214473	77/263 (29%)
Prss3	NP_035775.1	Tryp_SPc	24..242	CDD:238113	79/265 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910