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Protein Alignment CG6051 and SNX29

DIOPT Version :9

Sequence 1:	NP_001097943.1	Gene:	CG6051 / 43271	FlyBaseID:	FBgn0039492	Length:	989	Species:	Drosophila melanogaster
Sequence 2:	XP_011521040.1	Gene:	SNX29 / 92017	HGNCID:	30542	Length:	879	Species:	Homo sapiens

Alignment Length:	731	Identity:	145/731 - (19%)
Similarity:	237/731 - (32%)	Gaps:	236/731 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   374 NNHNSNSNSSTNPTV----EAATLRSPSMLSLSATSTP------TASPA------------PSPT 416
            :|.:.|..|...|||    :.:|....|:|..|.....      |||.|            |.|.
Human   188 DNKDLNGQSKFAPTVSDLLKESTQNVTSLLKESTQGVSSLFREITASSAVSILIKPEQETDPLPV 252

  Fly   417 PSHSIASTSSA--ATSSTNPPADWSDGDDEDEDDDDIDVDEEDI---ESSDDGTDEEQLLKDIVS 476
            .|.::::.:..  .........:....|||:::.:..||.::..   |||:|.:|...:  :|:|
Human   253 VSRNVSADAKCKKERKKKKKVTNIISFDDEEDEQNSGDVFKKTPGAGESSEDNSDRSSV--NIMS 315

  Fly   477 A-DCASGYLIPNTN---LGNLLQPQEVPLTDNF------VAS---------EDDEYGTAEQQGHQ 522
            | :...|   ||:|   ..|..:...:.|...|      |.|         |||.||.:..:.|:
Human   316 AFESPFG---PNSNGSQSSNSWKIDSLSLNGEFGYQKLDVKSIDDEDVDENEDDVYGNSSGRKHR 377

  Fly   523 GLEE--DEPSTSAAMLAATRTLQRLRLPSSDNEPLAEPTTIKASEEHMQQPSGRHRDSHSHRHHQ 585
            |..|  ::|......|:...:...|::..:|::.|. |.:...|......|.|...:...
Human   378 GHSESPEKPLEGNTCLSQMHSWAPLKVLHNDSDILF-PVSGVGSYSPADAPLGSLENGTG----- 436

  Fly   586 RHHHHHHHRHPHQHQHRQPHPHRTTRSGRKRCSLEAADPERIQPDREQNLASGDTSAASSLSDDV 650
                        ...|..|.|       ..|.|:||:.|             |..|..|||....
Human   437 ------------PEDHVLPDP-------GLRYSVEASSP-------------GHGSPLSSLLPSA 469

  Fly   651 SLAMRNTTARLKFKSTENLLHRLFVCIAGVADQLQTNFASDLRQILRSVFLMNMSTAQEEIDIPE 715
            |:....|.:.|: ::|..:::|        .|:|:....| ||.:|......:.:..||...:..
Human   470 SVPESMTISELR-QATVAMMNR--------KDELEEENRS-LRNLLDGEMEHSAALRQEVDTLKR 524

  Fly   716 KTKESE-----LFEFRASENDV----IQESAGSNQSIYSAEEVNPELDNVFSAGG----GNQATG 767
            |..|.|     ..:..|.||:|    :::..|:.|.: ..|....|:.|::|..|    ..|..|
Human   525 KVAEQEERQGMKVQALARENEVLKVQLKKYVGAVQML-KREGQTAEVPNLWSVDGEVTVAEQKPG 588

  Fly   768 QRHSAGASMQRNNTIDLASQPGE------------------------------GSPSGATTATSR 802
            :.....||......|::|...||                              |...|..:.||
Human   589 EIAEELASSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQELIDLRGPVPGDLSQTS- 652

  Fly   803 SHVTRSRSLGDQEAASSATSST-----------------------------------AQLRQLEQ 832
                ..:||.|.|.::.|..:.                                   .:.|.|..
Human   653 ----EDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNIYRRYTEFRSLHH 713

  Fly   833 QQQQQQLQIQLQR-QRNNSVGSNTPSS-------ASSTSS------------SSEQNSPVSARSG 877
            :.|.:..|::... ....::|:..|.|       ||..:|            :||..|...|:..
Human   714 KLQNKYPQVRAYNFPPKKAIGNKPPPSPAWMTAAASLLASLLPALPPLNLQVTSEVTSSQDAKFV 778

  Fly   878 SRRRLQSNNETQ---------MPSSATS----TSATLSP-----PAWIPDGKAPRCMA-----CQ 919
            ..||.|..|..:         :|..|.|    |...|.|     ..|.|:.:...|:.     ||
Human   779 EERRKQLQNYLRSVMNKVIQMVPEFAASPKKETLIQLMPFFVTSWCWDPENQTQTCLQGTLGYCQ 843

  Fly   920 TPFTAFRRRHHCRNCG 935
            :        |...:||
Human   844 S--------HFWISCG 851

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.