DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6051 and FAB1

DIOPT Version :9

Sequence 1:	NP_001097943.1	Gene:	CG6051 / 43271	FlyBaseID:	FBgn0039492	Length:	989	Species:	Drosophila melanogaster
Sequence 2:	NP_116674.2	Gene:	FAB1 / 850574	SGDID:	S000001915	Length:	2278	Species:	Saccharomyces cerevisiae

Alignment Length:	298	Identity:	71/298 - (23%)
Similarity:	116/298 - (38%)	Gaps:	81/298 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   745 SAEEVN-----PELDNVFSAGGGNQATGQRHSAGASMQRNN-----------------TIDLASQ 787
            |:||.:     |:..:|.|:..|   |...::..|::.|.|                 |.||.:.
Yeast     2 SSEEPHASISFPDGSHVRSSSTG---TSSVNTIDATLSRPNYIKKPSLHIMSTSTTSTTTDLVTN 63

  Fly   788 P----------GEGSPSGATTATSRSHVTRSRSLGDQEA-ASSATS---------------STAQ 826
            |          ...:.|...||||.||||.:.|..:.:| |:::||               |:..
Yeast    64 PILSNISVPKISPPTSSSIATATSTSHVTGTASHSNIKANANTSTSVNKKNLPPTTSGRIPSSTI 128

  Fly   827 LRQLEQQQQQQQLQIQLQRQRNNSVGSNTPSSASSTSSSSEQNSPVSARSGSRRRLQSNNE---- 887
            .|...:.:....||:.::...|....|...|.::.|:.....|.|:|.::...|...|:::
Yeast   129 KRYPSRYKPSHSLQLPIKNDSNFKRSSIYASKSTVTAIPIRNNRPISMQNSYARTPDSDHDDVGD 193

  Fly   888 ----TQMPSSA---------------------TSTSATLSPPAWIPDGKAPRCMACQTPFTAFRR 927
                .:..||:                     ||.:..||...|:.|..:..|.:|...|..|||
Yeast   194 EVSSIKSASSSLTASLSKSFLFAFYNNRKKDKTSNNGVLSKEYWMKDESSKECFSCGKTFNTFRR 258

  Fly   928 RHHCRNCGGVFCGVCSNASAPLPKYGLTKAVRVCRDCY 965
            :||||.||.:||..|: ......::|....:|||.:||
Yeast   259 KHHCRICGQIFCSSCT-LLIDGDRFGCHAKMRVCYNCY 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6051	NP_001097943.1	FYVE_LST2	902..966	CDD:277270	24/64 (38%)
FAB1	NP_116674.2	PHA03255	<64..>145	CDD:165513	19/80 (24%)
		FYVE_like_SF	236..296	CDD:333710	23/61 (38%)
		Fab1_TCP	797..1056	CDD:239450
		MSS4	1597..2278	CDD:227578
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2108
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030