Protein Alignment CG6051 and zfyve28

DIOPT Version :9

• Sequence 1: NP_001097943.1
• Gene: CG6051 / 43271
• FlyBaseID: FBgn0039492
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: NP_001072498.1
• Gene: zfyve28 / 779953
• XenbaseID: XB-GENE-1219057
• Length: 951
• Species: Xenopus tropicalis
• Alignment Length: 1159
• Identity: 351/1159 - (30%)
• Similarity: 496/1159 - (42%)
• Gaps: 395/1159 - (34%)

  Fly     1 MDTFKRWLNKPKADDKSLLARFFHADRSLTAVASELDSFDGRAEPDRCTRLVSRLRQNQDKVLAI 65
            |:.|::||.|||..|..|||:|::||..|..||:||||.|||.:|.|||.||::.|..||.||.|
 Frog     2 MNRFRKWLYKPKRSDPQLLAQFYYADEELNQVAAELDSLDGRKDPQRCTLLVNQFRSCQDNVLNI 66

  Fly    66 TNLIMEELLGEDRDPRAFRAKFPEEVLQENLAGQLWFGAECLAAGSSIMNRETESKEMRPLAQAV 130
            .|.||||.:..:|..|.|..|||||:..:|||||||||||||||||.|||||.||..|||||:.:
 Frog    67 INQIMEECIAHERANRDFCVKFPEEIRHDNLAGQLWFGAECLAAGSIIMNREIESMAMRPLAKDL 131

  Fly   131 TKSLGNVRVLLRDQCLKNNVPNSKTLHLDLNDSTTEQLYESLKIFDRLFAEFELSYVSAMVQVKS 195
            |:||..||.|:|||.|:           ||| ..||::.|||:.||.||||||||||||||.|||
 Frog   132 TRSLEEVRNLIRDQALR-----------DLN-IYTEKMKESLRHFDVLFAEFELSYVSAMVPVKS 184

  Fly   196 RHEYEMQQWIGVLFSETLQRALKIGLLDQEMVDAFDPGLMFSIPRLAIVAGLVVYAKGPLNMDMP 260
            ..||.:||.:.|||.||::||||:|.|.|:|:|.::|.|||:|||||||.||||||:||||::..
 Frog   185 PKEYYVQQEVIVLFCETVERALKLGYLTQDMIDDYEPALMFTIPRLAIVCGLVVYAEGPLNLERK 249

  Fly   261 GDQLSEMFRPFRTILIKIRDLLRNLNNQELYQLEKLLCTNEDI---------------------- 303
            .:.:||:||||.|:|.||||||:.|...||:.||:.||.::|:
 Frog   250 PEDMSELFRPFHTLLRKIRDLLQTLTEDELHTLERNLCISQDVEFPANADPEVPSAISPVLVTAL 314

  Fly   304 -----------NTKVPLG------------------------SSSIEAP----SPEHSSHPTTSS 329
                       ||:|.|.                        ||.:..|    ||.|.::.:..:
 Frog   315 PTEEPPMAKAENTEVELACSMQYDEQELEQLNMMVHRVGDEMSSLLSPPSVYQSPAHRANTSNEA 379

  Fly   330 SQNNNNSSN--------------NNHSSSSTNTTSTTTTTAGTTNTHRTVER------------- 367
            |.......|              :........:..:.||.:...|:....::
 Frog   380 SPCRRALDNLTDEEDRVFFMEDLDGSGEVLARSRPSETTISWVNNSCYNAKQPALYQDSVLQNGD 444

  Fly   368 LVD-------QRNNNHNSNSNSSTNPTVEAATLRSPSML-------------------------- 399
            |.|       ||:.::|:|.:.|......|:...|.|.|
 Frog   445 LADVVSVKDGQRDISNNNNIDGSKMLAASASLQNSCSCLEAPESQLYLNGWDTNGEDAETAEIIA 509

  Fly   400 ------SLSAT-----STPTASPAPSPT-PSHSIASTSSAATSSTNPPADWSDGDDEDEDDDDID 452
                  .:|||     .:.|.||..||. .|:.|.|:|...||            :|:::...:.
 Frog   510 HRTGGMKISATVIFNPKSLTNSPETSPNLASNRIPSSSDPLTS------------NEEDESHKLS 562

  Fly   453 VDEED--IES-----SDDGTDEEQL--LKDIVSAD---CASGYLIPNTNLGNL------LQPQEV 499
            :...:  |.|     |.:.|.|:.|  |:::.|:.   .||..||.:..||:|      :..:|:
 Frog   563 IAATNCLINSCVCCGSCEDTREDSLEGLRNVPSSGKVINASYSLIKSKELGHLDRSDCTVSAKEL 627

  Fly   500 PLTDNFVASEDDEYGTAEQQGHQGLEEDEPSTSAAMLAATRTLQRLRLPSSDNEPLAEPTTIKAS 564
            ...|:......::..|.::|.:....:..|..|.:         ::.:.|..:|||.      ||
 Frog   628 LKMDSPTVLLAEKETTRQEQPYPNSSKCLPLNSGS---------QVEMDSESDEPLT------AS 677

  Fly   565 EEHMQQPSGRHRDSHSHRHHQRHHHHHHHRHPHQHQHRQPHPHRTTRSGRKRCSLEAADPERIQP 629
            .:.::..|.|....:..|             |.:.....|    :.|:.....:..::..:.::.
 Frog   678 RDQLRSESNRQETGNKER-------------PSEEVEEPP----SDRASADNITSSSSSQDGLRD 725

  Fly   630 DREQNLASGD-------TSAASSL-------SDD-----VSLAMR------NTTARLKFKSTENL 669
            ....:::|.|       |.:.||:       |||     :.||::      ....|.:|.|:.:|
 Frog   726 SALSSISSSDYESVSVTTCSLSSIDSLSSCSSDDIDQEEIQLALQAAKIASRQKIRSRFHSSNDL 790

  Fly   670 LHRLFVCIAGVADQLQTNFASDLRQILRSVFLMNMSTAQEEIDIPEKTKESELFEFRASENDVIQ 734
            :|||||||:|||||||||:|||||.||:::|.: |:|.||..|   |.|:.:
 Frog   791 IHRLFVCISGVADQLQTNYASDLRSILKTLFEV-MATKQETDD---KGKQKK------------- 838

  Fly   735 ESAGSNQSIYSAEEVNPELDNVFSAGGGNQATGQRHSAGASMQRNNTIDLASQPGEGSPSGATTA 799
                :||.:
 Frog   839 ----ANQGL-------------------------------------------------------- 843

  Fly   800 TSRSHVTRSRSLGD----QEAASSATSSTAQLRQLEQQQQQQQLQIQLQRQRNNSVGSNTPSSAS 860
                   ||.:|.|    ||
 Frog   844 -------RSAALEDCALCQE--------------------------------------------- 856

  Fly   861 STSSSSEQNSPVSARSGSRRRLQSNNETQMPSSATSTSATLSPPAWIPDGKAPRCMACQTPFTAF 925
             |.:|||  ....||.|...                     .||.|:||.....|.||:.|||..
 Frog   857 -TITSSE--LAAKARDGEFE---------------------DPPDWVPDEVCSLCTACKAPFTVI 897

  Fly   926 RRRHHCRNCGGVFCGVCSNASAPLPKYGLTKAVRVCRDCYVREV------RSGM 973
            ||:||||:||.:||..||:.|||||:||..|.||||..||:..|      |:||
 Frog   898 RRKHHCRSCGKIFCSRCSSHSAPLPRYGQMKPVRVCTHCYMFHVTPFYSDRAGM 951

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6051	NP_001097943.1	FYVE_LST2	902..966	CDD:277270	36/63 (57%)
zfyve28	NP_001072498.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	360..382		5/21 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	527..557		12/41 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	641..726		16/116 (14%)
		FYVE_LST2	874..938	CDD:277270	36/63 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	406	1.000	Domainoid score	I699
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	502	1.000	Inparanoid score	I1319
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D215217at33208
OrthoFinder	1	1.000	-	-		FOG0005719
OrthoInspector	1	1.000	-	-		otm49480
Panther	1	1.100	-	-	LDO	PTHR46465
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2108
SonicParanoid	1	1.000	-	-		X4713
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.190