DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6051 and rufy2

DIOPT Version :9

Sequence 1:	NP_001097943.1	Gene:	CG6051 / 43271	FlyBaseID:	FBgn0039492	Length:	989	Species:	Drosophila melanogaster
Sequence 2:	NP_001231848.1	Gene:	rufy2 / 569096	ZFINID:	ZDB-GENE-070424-66	Length:	698	Species:	Danio rerio

Alignment Length:	389	Identity:	84/389 - (21%)
Similarity:	147/389 - (37%)	Gaps:	95/389 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   644 SSLSDDVSLAMRNTTARLKFKS----TENLL------HRLFVCIAGVADQLQTNFAS-------- 690
            |.|.:::::| :|...:|:.::    |||.:      .||.|....::.:|.|...|
Zfish   326 SKLIEELAIA-KNNIIKLQEENHQLRTENSVILMKAQQRLAVTEGDLSCELDTYKQSRQGLDEMY 389

  Fly   691 -----------DLRQILRSVFLMNMSTAQE--------EIDIPEKTK-----ESELFEFRASEND 731
                       .|||.:.:..::.:|..||        |.||.||..     ..:|.|.:|...:
Zfish   390 NEARRQLKEECQLRQDVENELVVQVSMKQEMEMAMKLLEKDIHEKQDTLIGLRHQLDEVKAINVE 454

  Fly   732 VIQESAGSNQSIYSAEEVNPELDNVFSAGGGNQATGQRHSAGASMQRNNTIDLASQPGEGSPSGA 796
            :.|:...|:.|:....::...|:.     ..||.|       |:|::   ::...|..|...:.|
Zfish   455 MYQKMQSSDDSMRQKNDMIARLEE-----KTNQIT-------ATMKQ---LEQRLQDAERERASA 504

  Fly   797 TTATSRSHVTRSRSLGDQEAASSATSSTAQLRQLEQQQQQQQLQIQLQRQRNNSVGSNTPSSASS 861
            .....:.         .|:..:.|.|...|:.|.|:|..|.:..::::|....::.:.......:
Zfish   505 EDGVRKF---------KQDFTNKAESLQKQIVQREKQMTQLETDLKIERDWRQTLQNELERERET 560

  Fly   862 TSSSSEQNSPVSARSGSRRRLQSNNETQMPSSA-------------------------TSTSATL 901
            .:..:.:...::.......|||..| ||:....                         .:..|..
Zfish   561 ITQLAAEAQQINGLKKEFHRLQDEN-TQLKGICEEQEHALEELGCKLSESKLKIEDIKEANKALQ 624

  Fly   902 SPPAWIPDGKAPRCMACQTPFTAFRRRHHCRNCGGVFCGVCSNASAPLPKYGLTKAVRVCRDCY 965
            ....|:.|..|..|..|:..|:..||:|||||||.:||..||:...|||  ...|.||||..|:
Zfish   625 GGQVWLKDKDATHCKLCEKEFSISRRKHHCRNCGEIFCNACSDNELPLP--ASPKPVRVCDTCH 686

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6051	NP_001097943.1	FYVE_LST2	902..966	CDD:277270	28/64 (44%)
rufy2	NP_001231848.1	RUN	135..258	CDD:280855
		Taxilin	300..625	CDD:286771	56/324 (17%)
		FYVE_RUFY2	626..696	CDD:277298	28/63 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584059
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840