DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6051 and Rufy3

DIOPT Version :9

Sequence 1:	NP_001097943.1	Gene:	CG6051 / 43271	FlyBaseID:	FBgn0039492	Length:	989	Species:	Drosophila melanogaster
Sequence 2:	XP_006535172.1	Gene:	Rufy3 / 52822	MGIID:	106484	Length:	687	Species:	Mus musculus

Alignment Length:	280	Identity:	57/280 - (20%)
Similarity:	102/280 - (36%)	Gaps:	51/280 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   702 MNMSTAQEEIDIPEK-----TKESELFEFRASENDVIQESAGSNQSIYSAEEVNPELDNVFSAGG 761
            |.::....|.|:.||     :...:|.:.||.::::..:...|:..:....|:|..|:
Mouse   441 MELAMKMLEKDVCEKQDALVSLRQQLDDLRALKHELAFKLQSSDLGVKQKSELNSRLE------- 498

  Fly   762 GNQATGQRHSAGASMQRNNTIDLASQPGEGSPSGATTATSRSHVTRSRSLGDQEAASSATSSTAQ 826
              :.|.|  .|....|....:..|.:             .|........|..|:......|...:
Mouse   499 --EKTNQ--MAATIKQLEQRLRQAER-------------GRQSAELDNRLFKQDFGDKINSLQLE 546

  Fly   827 LRQLEQQQQQQQLQIQLQRQRNNSVGSNTPSSASSTSSSSEQNSPVSARSGSRRRLQSNNETQMP 891
            :..|.:|:.|.:|:::.:::| .|....||...:...         ..|...:.|:|..| .::.
Mouse   547 VEALTRQRTQLELELKQEKER-KSQNRGTPGKGAQKP---------ELRMDGKHRIQEEN-VKLK 600

  Fly   892 SSATSTSATLSPPAWIPDG------KAPRCMACQTPFTAFRRRHHCRNCGGVFCGVCSNASAPLP 950
            .....:...|:.|| ...|      |...|..||...:.  .::.||||.|.||..|:....|||
Mouse   601 KPLEESHRLLTHPA-EEQGQPSLSEKPQVCQLCQEDDSL--TKNTCRNCRGTFCNACTTNELPLP 662

  Fly   951 KYGLTKAVRVCRDCYVREVR 970
              ...|..|||..|:.:.::
Mouse   663 --SSIKPERVCNPCHEQLIK 680

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6051	NP_001097943.1	FYVE_LST2	902..966	CDD:277270	23/69 (33%)
Rufy3	XP_006535172.1	RUN	171..292	CDD:367169
		Smc	<340..>570	CDD:224117	26/153 (17%)
		FYVE_RUFY3	629..675	CDD:277283	18/49 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839956
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930