DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6051 and Rundc3a

DIOPT Version :9

Sequence 1:	NP_001097943.1	Gene:	CG6051 / 43271	FlyBaseID:	FBgn0039492	Length:	989	Species:	Drosophila melanogaster
Sequence 2:	XP_006533751.1	Gene:	Rundc3a / 51799	MGIID:	1858752	Length:	465	Species:	Mus musculus

Alignment Length:	395	Identity:	79/395 - (20%)
Similarity:	136/395 - (34%)	Gaps:	105/395 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 GQLWFGAECLAAGSSIMNRETESKE-MRPLAQAVTKSLGNVRVLLRDQCLKNNVPNSKTLHLDLN 161
            ||..|......|.|.:.|....|.| |..::.|..|....:||.|.::.:...:..:      |.
Mouse   100 GQRGFWDYIRLACSKVPNNCVSSIENMENISTARAKGRAWIRVALMEKRMSEYITTA------LR 158

  Fly   162 DS-TTEQLYESLKIFDRLFAEFELSYVSAMVQVKSRHEYEMQQWIGVLFSETLQRALKIGLLDQE 225
            |: ||.:.|:|..|..|    .|.:.::.|:...|..::..              .||..:||.:
Mouse   159 DNRTTRRFYDSGAIMLR----EEATVLTGMLIGLSAIDFSF--------------CLKGEVLDGK 205

  Fly   226 --MVDAFDPGLMFS--------------------------IPRLAIVAG---------------L 247
              :|..:.|.|.|:                          .|.|.:|..               .
Mouse   206 TPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPLVTDEDSWYNKWHKMEQKFR 270

  Fly   248 VVYA-KGPLN--MDMPGDQLSEMFRPFRTILIKIRDLLRNLNNQELYQLEKLLCTNEDINTKVPL 309
            :||| ||.|.  :.:...||.::....|.:.:::.:.... |.:|..:||.::.   ::..::|
Mouse   271 IVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQ-NQREKRELEGVIL---ELQEQLP- 330

  Fly   310 GSSSIEAPSPEHSSHPTTSSSQNNNNSSNNNHSSSSTNTTSTTTTTAGTTNTHRTVERLVDQRNN 374
                 :.|.|     |.|....       .:|:..:..:...||:......:..|:.|.....|:
Mouse   331 -----DPPPP-----PRTGLIP-------GDHAPLAQGSKELTTSLVNQWPSLSTLHRPEGASNS 378

  Fly   375 N-HNSNSNSSTNPTVEAATLRSPS--MLSLSATSTPTASPAPSPTPS--------HSIASTSSAA 428
            . :..:|..||.|....|:|.|.|  :........|.......||||        .||.|..|.|
Mouse   379 KLYRRHSFMSTEPLSAEASLSSDSQRLGEAKRDEEPWGPIGKDPTPSMLGLCGSLASIPSCKSLA 443

  Fly   429 TSSTN 433
            :..:|
Mouse   444 SFKSN 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6051	NP_001097943.1	FYVE_LST2	902..966	CDD:277270
Rundc3a	XP_006533751.1	RUN	60..197	CDD:367169	25/120 (21%)
Rundc3a	XP_006533751.1	UPF0242	<266..>329	CDD:369080	13/66 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839963
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930