DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6051 and rundc3b

DIOPT Version :9

Sequence 1:	NP_001097943.1	Gene:	CG6051 / 43271	FlyBaseID:	FBgn0039492	Length:	989	Species:	Drosophila melanogaster
Sequence 2:	NP_001007417.1	Gene:	rundc3b / 492775	ZFINID:	ZDB-GENE-041114-121	Length:	450	Species:	Danio rerio

Alignment Length:	529	Identity:	104/529 - (19%)
Similarity:	170/529 - (32%)	Gaps:	207/529 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 EEVLQENLAGQL-WFGAE------------CLAAGSSIMNRETESKEMRPLAQAVTKSLGNVRVL 140
            |.:|...|.||: |||.|            |.....|.::   ..:.|..:..:..|....:||.
Zfish    62 EHILSHRLKGQVSWFGYESPRSFWDFIRMACSKVPHSCIH---SIENMENVRSSRAKGRAWIRVA 123

  Fly   141 LRDQCLKNNVPNSKTLHLDLND-STTEQLYESLKIFDRLFAEFELSYVSAMVQVKSRHEYEMQQW 204
            |.::.|      |:.:...|.| .||.:.||.                .|::         :.:.
Zfish   124 LMEKRL------SEYISAALRDFKTTRRFYEE----------------GALL---------LGEE 157

  Fly   205 IGVLFSETLQRALKIGLLDQEMVDAFDPGLMFSIPRLAIVAGLVVYAKGP-LNMDMPGDQLSEMF 268
            .|:| ::||     |||      :|.|    ||.           ..||. |:.|.|   :...:
Zfish   158 AGLL-ADTL-----IGL------NAID----FSF-----------CLKGEGLDEDCP---VVIDY 192

  Fly   269 RPFRTILIKIRDLLRNLNNQELYQLEKLLCTNEDINTKVPLGSSSIEAPSPEHSSHPTTSSSQNN 333
            .|:    :|......::::.|           |::.|   ||||..||.:||  ||...|...:.
Zfish   193 TPY----LKFTQTSDSISSDE-----------EEMRT---LGSSGSEAGTPE--SHMAASLMADQ 237

  Fly   334 NNSSNNNH---------------------------SSSSTNTTSTTTTTAGTTNTHR-------- 363
            ::..:.:.                           |.|.:...:.......|..:|:
Zfish   238 SSWFSKSKRLEQKYRVVLEQRGYLEELVRLREAQLSESVSQNKALLQRLTDTEISHKLEKEQLEI 302

  Fly   364 TVERLVDQRN--NNHNSNSNSSTNPTVEAATLRSPSMLSLSATSTPTASPAPSPTPSHSIASTSS 426
            .:..|.||..  .||:               |||...|:...|:   ..|:|.....:::|..:.
Zfish   303 IILELQDQLTVLKNHD---------------LRSRQELTSHLTN---QWPSPGALDGNAVALDTL 349

  Fly   427 AATSSTNPPADWSDGDDEDEDDDDIDVDEEDIESSDDGTDEEQLLKDIVSADCASGYLIPNTNLG 491
            .....|.|   |     |::....::....|:..|....|..||                ||:
Zfish   350 LYRKRTGP---W-----EEKSFPSLEQLSADMSLSQTSLDPVQL----------------NTH-- 388

  Fly   492 NLLQPQEVPLTDNFVASEDDEYGTAEQQGHQGLEEDEPST-----SAAMLAATRTLQRLRLPSSD 551
                            |.|.:.|.|  ..|:..:||.||.     |...:|:.::|..|:    .
Zfish   389 ----------------SLDSKAGLA--HWHREGKEDTPSLRGLCGSLTSMASYKSLASLK----S 431

  Fly   552 NEPLAEPTT 560
            :|.||.|||
Zfish   432 SEYLASPTT 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6051	NP_001097943.1	FYVE_LST2	902..966	CDD:277270
rundc3b	NP_001007417.1	RUN	56..179	CDD:280855	36/177 (20%)
rundc3b	NP_001007417.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	203..225		9/35 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584063
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930