DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6051 and rundc3ab

DIOPT Version :9

Sequence 1:	NP_001097943.1	Gene:	CG6051 / 43271	FlyBaseID:	FBgn0039492	Length:	989	Species:	Drosophila melanogaster
Sequence 2:	NP_956443.1	Gene:	rundc3ab / 393118	ZFINID:	ZDB-GENE-040426-842	Length:	428	Species:	Danio rerio

Alignment Length:	416	Identity:	85/416 - (20%)
Similarity:	136/416 - (32%)	Gaps:	124/416 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 EEVLQENLAGQ-LWFGAE------CLAAGSSIMNRETESKE-MRPLAQAVTKSLGNVRVLLRDQC 145
            |.:|.....|. .||..:      ...|.|.:.|....|.| |..:..:..|....:||.|.::.
Zfish    66 EHILSHRFKGSGSWFDGQRSFWDFIRLACSKVPNNCISSIENMENINSSRAKGRAWLRVALMEKR 130

  Fly   146 LKNNVPNSKTLHLDLNDS-TTEQLYESLKIFDRLFAEFELSYVSAMVQVKSRHEYEMQQWIGVLF 209
            |...:..:      |.|| ||.:.|:...|..|    .|.:.::.|:             || |.
Zfish   131 LSEYIATA------LRDSRTTRRFYDEGAIMLR----EEATVLTGML-------------IG-LG 171

  Fly   210 SETLQRALKIGLLD--QEMVDAFDPGLMFSIPRLAIVAGLVVYAKGPLNMDMPG---------DQ 263
            :......||...||  .|.|..:.|.|.|:            .:...|:.|..|         |.
Zfish   172 AIDFSFCLKGEALDGKSEAVIDYTPYLKFT------------QSYDYLSDDEDGQSVDSSNSDDS 224

  Fly   264 LSEMFRP-------FRTILIKIRDLLRNLNNQELYQLEKLLCTNED-------INTKVPLGSSSI 314
            :...:.|       :|....|:....:.:|.|:.| ||:|:...|.       .|.|:..|...:
Zfish   225 VEHPYIPLVTDEESWRNKCRKMEQRFKIVNAQKGY-LEELVRLRESQLKNVEMENKKLTAGLEEL 288

  Fly   315 EAPSPEH---------------------SSHPTTS-----------SSQNNNNSSNNN--HSSSS 345
            :..|.:.                     .|||.:.           |.||.||..::.  |..|.
Zfish   289 QQQSQKEKGELENIILELQEQLTSLIPGESHPLSKDLSIPLVNQWPSLQNYNNQEDSKLYHRGSF 353

  Fly   346 TNTTSTTTTTAGTTNTHRTVERLVDQRNNNHNSNSNSSTNPTVEAATLRSPSMLSL--SATSTPT 408
            .:.....:.|.|:..|         :|..|..|...:..:.|        ||||.|  |.:|.|:
Zfish   354 PSPEPHISLTTGSQRT---------ERKQNGKSWCTAEKDYT--------PSMLGLCGSMSSLPS 401

  Fly   409 ASPAPSPTPSHSIASTSSAATSSTNP 434
            ....||...:..:.:.|:..:.:..|
Zfish   402 CKSLPSLRSTECLVNISAEPSPALTP 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6051	NP_001097943.1	FYVE_LST2	902..966	CDD:277270
rundc3ab	NP_956443.1	RUN	60..181	CDD:280855	30/138 (22%)
		YlqD	233..>313	CDD:287979	13/80 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	349..375		6/34 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584066
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930