Protein Alignment CG6051 and Zfyve26

DIOPT Version :10

• Sequence 1: NP_001097943.1
• Gene: CG6051 / 43271
• FlyBaseID: FBgn0039492
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: XP_038968219.1
• Gene: Zfyve26 / 314265
• RGDID: 1307820
• Length: 2544
• Species: Rattus norvegicus
• Alignment Length: 1144
• Identity: 217/1144 - (18%)
• Similarity: 350/1144 - (30%)
• Gaps: 466/1144 - (40%)

  Fly    25 ADRSLTAVASELDSFDGRA--------EPDRCTRLVSRLRQNQDKVLA----ITNLIMEELLGED 77
            |:|.|::      |.:||.        .||. .|....:.|...|:|:    :|.|...|.| |:
  Rat   993 AERRLSS------SLEGRGRRLDQVVLNPDG-MRGFPFVLQQISKILSYPLTVTGLTKSETL-EE 1049

  Fly    78 RDPRAFRAKFPEEVLQENLAGQLW--FGAECLAAGSSIMNRETESKEMRPLAQAVTKSLGN---- 136
            |...|.|... .|:||     ..|  ...:|:|:.:|:..:..::  ::.|.:|:|.| |.
  Rat  1050 RGGGAPRCSI-SELLQ-----MCWPSLTEDCIASHTSLSQQLDQA--LQSLREALTLS-GTEPKS 1105

  Fly   137 --VRVLLRDQCLKNNVPNSKTLHLD---LNDSTTEQLYESLKIFDRLFAEFELSYVSAMVQVKSR 196
              :..|:.....|.....:..:|:.   |..:..:|.....:..|.:.|.|  ||.|::.:|..|
  Rat  1106 TPLTCLVEQAAQKAPEAEAHPVHIQSQLLQKTLGKQTLAGPRQTDYVGAFF--SYCSSLAKVLLR 1168

  Fly   197 HEYEMQQWIGVLFSETLQRALKIGLLDQEMVDAFDPGLMFSIPRLAIVAGLVVYAKGPLNMDMPG 261
            .          |.|:.....:|:|          :|.::.......:|:.|:      |...:|.
  Rat  1169 S----------LSSDPDNVEVKVG----------NPFVLLQQSSSQLVSHLL------LERQVPP 1207

  Fly   262 DQLSEMFRPFRTILIKIRDLLRNLNNQELYQLEKLLCTNEDINTKVP--LGSSSIEAPSPEHSSH 324
            |:|:                              .|...|.:|..||  :.|...|
  Rat  1208 DRLA------------------------------ALLAQEHLNLSVPQVIVSCCCE--------- 1233

  Fly   325 PTT--SSSQNNNNSSNNNHSSSSTNTTSTTTTTAGTTNTHRTVERLVDQRNNNHNSNSNSSTNPT 387
            |.|  .|.|:...||...|..                        ::.|.:.:|..:.
  Rat  1234 PLTLCLSRQSQQASSLTAHLG------------------------MLAQGHASHLLDG------- 1267

  Fly   388 VEAATLRSPSMLSLSATSTPTASPAPS------PTPSHSIASTSSAATSSTNPPADWSDGDDEDE 446
                       |.||...:|..|..||      .:|..|:.:.:::|.:...
  Rat  1268 -----------LPLSVLGSPRPSENPSAERKSDSSPKDSLPAFTASALAFLK------------- 1308

  Fly   447 DDDDIDVDEEDIESSDDGTDEEQLLKDIVSADCASGYLI--PNTNLGNLLQPQEVPLTDNFVASE 509
                               ...::|..:.....:.|..:  |:.:...|...:|.|||...||.|
  Rat  1309 -------------------SRSKILAMVACLRASRGTKVSRPSLSWKELRGRREAPLTAEKVAQE 1354

  Fly   510 DDEYGTAEQQGHQGLEEDEPSTSAAMLAATRTLQRLRLPSSDNEP-------------------- 554
            .:.           |.|..|...||:||....||:    :|::.|
  Rat  1355 CEH-----------LLEQFPVFEAALLANWEPLQQ----ASESRPSLAASLCGQARLSTVLLGLH 1404

  Fly   555 --LAEPTTIKASEEHMQQPSGRHRDSHSHRHHQRHHHHHHHRHPHQHQHRQPHPHRTTRSGRKRC 617
              ||:....:|.||
  Rat  1405 STLAQDVVTEAFEE--------------------------------------------------- 1418

  Fly   618 SLEAAD-PERIQPDREQNLASGDTSAASSLSDDV-------------------SLAMRNTTARLK 662
            :|.|.| |..:|   ..::...|:...||:.|.|                   ..::|:..| |:
  Rat  1419 ALVARDWPRALQ---LIDVYGQDSDDLSSVRDSVLTCATVCDKEGWQYLFPVKDASLRSQLA-LR 1479

  Fly   663 FKS---TENLLHRLFVCIAGVA--DQLQTNF---ASDLR-----------------QILRSVFLM 702
            |..   .|:.|..|..|::.:|  ::|::..   .::||                 |.|||....
  Rat  1480 FVDKWPLESCLEILAYCVSDMAVPEELKSELQRKLTELRVYQKILGLQDPPVWCDWQTLRSCCAE 1544

  Fly   703 NMSTAQEEIDIPEKTKESELFEFRASENDVIQE---SAGSNQSIYSAEEVNPELDNVFSAGGGNQ 764
            :.||.   :|:...::|.||.|.......:.:|   |......:|..|....|
  Rat  1545 DPSTV---MDMMLGSQEYELCEEWGCLYPIPREHLVSLHHKHLLYLLERREYE------------ 1594

  Fly   765 ATGQRHSAGASMQR----NNTIDLASQPGEGSPSGATT---------------ATSRSHVTRSRS 810
                  .|...:||    ...:::..:..:..||.||:               .|.|.|..::..
  Rat  1595 ------KALQLLQRIPDPTMCLEVTERSLDQHPSLATSHFLANYLTSHFYGELTTDRHHEIQALY 1653

  Fly   811 LG--------DQEAASSATSSTAQLRQLEQ--------------QQQQQQL-------------- 839
            :|        :|..||.|..|::.|..|||              |..||.|
  Rat  1654 MGSKVLLTLPEQHRASYAHLSSSPLLMLEQLLMNMKVDWATTAVQTLQQLLAGQDIGFTLDEVDS 1718

  Fly   840 -----------------------QIQLQRQRNNSVGSNTPSSASSTSSSSEQNSPVSARSGS--- 878
                                   .|.||...:.:....|.|.:||...|:...:|..|..||
  Rat  1719 LLSRYAGKALDLPYPLREKRSDSMIHLQEPVHQASDPETLSRSSSAEFSAAAAAPAPAAPGSALV 1783

  Fly   879 ---RRRLQSNNETQMPSSATSTSATLSPPA---WIPDGKAPRCM-ACQTPFTAFRRRHHCRNCGG 936
               ..:.::..:||.|.......   :|||   |:||.....|| .|:..||.|.||||||.||.
  Rat  1784 CSPSPKERAFPQTQPPLEFVPPE---TPPARDQWVPDETESMCMVCCREHFTMFNRRHHCRRCGR 1845

  Fly   937 VFCGVCSNASAPLPKYGLTKAV----------RVCRDCY 965
            :.||.||           ||.:          |||..||
  Rat  1846 LVCGSCS-----------TKKMVVEGCRENPTRVCDQCY 1873

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6051	NP_001097943.1	FYVE_LST2	902..966	CDD:277270	31/78 (40%)
Zfyve26	XP_038968219.1	FYVE_ZFY26	1814..1874	CDD:277263	28/71 (39%)