Protein Alignment CG6051 and ZFYVE26

DIOPT Version :9

• Sequence 1: NP_001097943.1
• Gene: CG6051 / 43271
• FlyBaseID: FBgn0039492
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: XP_016876613.1
• Gene: ZFYVE26 / 23503
• HGNCID: 20761
• Length: 2545
• Species: Homo sapiens
• Alignment Length: 998
• Identity: 215/998 - (21%)
• Similarity: 322/998 - (32%)
• Gaps: 300/998 - (30%)

  Fly   107 LAAGSSIMNRETESKEMRPLAQAVTKSLGNVRVLLRDQCLKNNVPNSKTLHLDLNDSTTEQLYES 171
            |.:.|...:...|.|...|...::|:.|......|.:.|:.::...|:.|     |...:.|.|:
Human  1038 LMSASQTKSESVEEKGGGPPRCSITELLQMCWPSLSEDCVASHTTLSQQL-----DQVLQSLREA 1097

  Fly   172 LKIFDRLFAEFELSYVSAMVQVKSR-------HEYEMQ-------------------QWIGVLFS 210
            |::     .|.....:|::|:..::       |..::|                   .::|..||
Human  1098 LEL-----PEPRTPPLSSLVEQAAQKAPEAEAHPVQIQTQLLQKNLGKQTPSGSRQMDYLGTFFS 1157

  Fly   211 --ETLQRAL-------------KIG---LLDQEMVDAFDPGLMF--SIP--RLAIVAGLVVYAKG 253
              .||...|             |:|   :|.|:........|:|  .:|  |||     .:.|:.
Human  1158 YCSTLAAVLLQSLSSEPDHVEVKVGNPFVLLQQSSSQLVSHLLFERQVPPERLA-----ALLAQE 1217

  Fly   254 PLNMDMPGDQLSEMFRPFRTILIKIR------DLLRNLNNQELYQLEKLLCTNEDINTKVPLGSS 312
            .|::.:|...:|....|.  .|...|      .||..|..  |.||....|. :|:....|....
Human  1218 NLSLSVPQVIVSCCCEPL--ALCSSRQSQQTSSLLTRLGT--LAQLHASHCL-DDLPLSTPSSPR 1277

  Fly   313 SIEAP--------SPEHSSHPTTSSSQNNNNSSN------------------NNHSSSSTNTTST 351
            :.|.|        ||..||.|..:||......|.                  :..|.|.......
Human  1278 TTENPTLERKPYSSPRDSSLPALTSSALAFLKSRSKLLATVACLGASPRLKVSKPSLSWKELRGR 1342

  Fly   352 TTTTAGTTNTHRTVERLVDQRNNNHNSNSNSSTNPTVEAATLRSPSML--------SLSATSTPT 408
            ...........|..|||::|             .|..||..|.:...|        ||:......
Human  1343 REVPLAAEQVARECERLLEQ-------------FPLFEAFLLAAWEPLRGSLQQGQSLAVNLCGW 1394

  Fly   409 ASPAPSPTPSHS-IA-STSSAATSSTNPPADWSDGDDEDE----DDDDIDVDEEDIESSDDGTDE 467
            ||.:......|| || ...|.|...:....|||......|    |.||:...::.:.|.....|:
Human  1395 ASLSTVLLGLHSPIALDVLSEAFEESLVARDWSRALQLTEVYGRDVDDLSSIKDAVLSCAVACDK 1459

  Fly   468 EQLLKDIVSADCASGYLIP--NTNLGNLLQPQEV---PLTDNFVASEDDEYGTAEQQGHQGLEED 527
            |           ...||.|  :.:|.:.|..|.|   ||..   ..|...|..::....:|| :.
Human  1460 E-----------GWQYLFPVKDASLRSRLALQFVDRWPLES---CLEILAYCISDTAVQEGL-KC 1509

  Fly   528 EPSTSAAMLAATRTLQRLRLPS--SDNEPL-----AEPTTI-----KASEEHMQQ------PSGR 574
            |.....|.|...:.:..|:.|.  .|.:.|     .:|:|:     :|.|..:.:      |..|
Human  1510 ELQRKLAELQVYQKILGLQSPPVWCDWQTLRSCCVEDPSTVMNMILEAQEYELCEEWGCLYPIPR 1574

  Fly   575 HRDSHSHRHHQRHHHHHHHRHPH----QHQHRQPHPHRTTRSGRKRCSLEAADPERIQPDREQNL 635
               .|....||:|..|...|..|    |...|.|.|        ..| ||..:
Human  1575 ---EHLISLHQKHLLHLLERRDHDKALQLLRRIPDP--------TMC-LEVTE------------ 1615

  Fly   636 ASGDTSAASSLSDDVSLAMRNTTARLKFKSTENLLHRLFVCIAGVADQLQTNFASDLRQILRSVF 700
                    .||....|||            |.:.|          |:.|.|:|...|..:.....
Human  1616 --------QSLDQHTSLA------------TSHFL----------ANYLTTHFYGQLTAVRHREI 1650

  Fly   701 LMNMSTAQEEIDIPEKTKESELFEFRASENDVIQESAGSNQSIYSAEE--VNPELDNVFSAGGGN 763
            ......::..:.:||        :.|||.:.:      |:..::..|:  :|.::|....|....
Human  1651 QALYVGSKILLTLPE--------QHRASYSHL------SSNPLFMLEQLLMNMKVDWATVAVQTL 1701

  Fly   764 QATGQRHSAGASMQRNNTIDLASQPGEGSPSGATTATSRSHVTRSRSLGDQEAASSATSSTAQLR 828
            |........|.:|...::  |.|:..|       .|....:..|.:    :.|.|.:|.|...|:
Human  1702 QQLLVGQEIGFTMDEVDS--LLSRYAE-------KALDFPYPQREK----RSAFSLSTDSVIHLQ 1753

  Fly   829 QLEQQQQQQQLQIQLQRQRNNSVGSNTPSSASSTSSSS--EQNSPVSARSGSRRRLQSNNETQMP 891
            ::..|....:   .|.|..:.......|...||..|.|  |::.|               .|| |
Human  1754 EIVHQAADPE---TLPRSPSAEFSPAAPPGISSIHSPSLRERSFP---------------PTQ-P 1799

  Fly   892 SSATSTSATLSPPA---WIPDGKAPRCM-ACQTPFTAFRRRHHCRNCGGVFCGVCSNASAPLPKY 952
            |......||  |||   |:||.....|| .|:..||.|.||||||.||.:.|..||
Human  1800 SQEFVPPAT--PPARHQWVPDETESICMVCCREHFTMFNRRHHCRRCGRLVCSSCS--------- 1853

  Fly   953 GLTKAV----------RVCRDCY 965
              ||.:          |||..||
Human  1854 --TKKMVVEGCRENPARVCDQCY 1874

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6051	NP_001097943.1	FYVE_LST2	902..966	CDD:277270	30/78 (38%)
ZFYVE26	XP_016876613.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149918
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930