Protein Alignment CG6051 and PLEKHM2

DIOPT Version :9

• Sequence 1: NP_001097943.1
• Gene: CG6051 / 43271
• FlyBaseID: FBgn0039492
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: XP_016856246.1
• Gene: PLEKHM2 / 23207
• HGNCID: 29131
• Length: 1032
• Species: Homo sapiens
• Alignment Length: 637
• Identity: 126/637 - (19%)
• Similarity: 207/637 - (32%)
• Gaps: 229/637 - (35%)

  Fly    59 QDKVLAITNLIMEELLGEDRDPRAFRAKFPEEVLQ---ENLAGQLWFGAECLAAGSSIM----NR 116
            :|::.||.|                    .::|||   |:|...|.:|.:.|::|..::    .|
Human    42 EDEIPAIRN--------------------HDKVLQRLCEHLDHALLYGLQDLSSGYWVLVVHFTR 86

  Fly   117 ETESKEMRPLAQAVTKSLGNVRVLLRDQCLKNNVPNSKTLHLDLNDSTTEQLYESLKIFDRLFAE 181
            ....|::..| |.|..:||..|.               .|:|.||::       ||:.:.|||
Human    87 REAIKQIEVL-QHVATNLGRSRA---------------WLYLALNEN-------SLESYLRLF-- 126

  Fly   182 FELSYVSAMVQVKSRHEYEMQQWIGVLFSETLQRALKIGLLDQEMVDAFDPGLMFSIPRLAIVAG 246
                                |:.:|:|....::.||         |.:.|...:|    |.:|:|
Human   127 --------------------QENLGLLHKYYVKNAL---------VCSHDHLTLF----LTLVSG 158

  Fly   247 LVVYAKGPLNMDMP----GDQLSEMFRPFRTILIKIRDLL-RNLNNQELYQLEKLLCTNEDINTK 306
            | .:.:..|::|.|    ...:.:.::|  ..|:...|.| .:::..:...|...   |...:|.
Human   159 L-EFIRFELDLDAPYLDLAPYMPDYYKP--QYLLDFEDRLPSSVHGSDSLSLNSF---NSVTSTN 217

  Fly   307 VPLGSSSIEAPS----------PEHSSHPTTSSSQNNNNSSNNNHSSSSTNTTSTTTTTAGTTNT 361
            :....|:| |||          |...|.|:|.....:...:.:...|::::.||:..:|...|
Human   218 LEWDDSAI-APSSEDYDFGDVFPAVPSVPSTDWEDGDLTDTVSGPRSTASDLTSSKASTRSPT-- 279

  Fly   362 HRTVERLVDQRNNNHNSN-----SNSSTNPT-------VEAATLRSPSMLS-------------- 400
                     ||.|..|..     |:|.|.|.       .||..|..|...:
Human   280 ---------QRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQALDPPDACTELEVIRVTKKKKIG 335

  Fly   401 --LSATSTPTASPAPSPTPSHSIASTSSAATSSTNPPADWSDGDD-----EDEDDDDIDVDEEDI 458
              ..:.|...|||. .|..|....:......|....|:...|..|     ..|:.:......|..
Human   336 KKKKSRSDEEASPL-HPACSQKKCAKQGDGDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTESS 399

  Fly   459 ESSDDG--------TDEEQL---LKDIVSADCASGYLIPNT------------------------ 488
            |.|:.|        |..|:|   |..::  |..:|.|.|:|
Human   400 ERSEPGLLIPEMKDTSMERLGQPLSKVI--DQLNGQLDPSTWCSRAEPPDQSFRTGSPGDAPERP 462

  Fly   489 ---------------------------------NLGNLLQPQEVPLTDNFVASEDDEYGTAEQQG 520
                                             :...|.||..||.:.. .|.:::|.|..|.|.
Human   463 PLCDFSEGLSAPMDFYRFTVESPSTVTSGGGHHDPAGLGQPLHVPSSPE-AAGQEEEGGGGEGQT 526

  Fly   521 HQGLEEDEPSTSAAMLAATRTLQRLRLPSSDNEPLAEPTTIKASEEHMQQPS 572
            .:.||  :.:..|..|.|..:|.| ..|.|:.||..:....:...:   |||
Human   527 PRPLE--DTTREAQELEAQLSLVR-EGPVSEPEPGTQEVLCQLKRD---QPS 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6051	NP_001097943.1	FYVE_LST2	902..966	CDD:277270
PLEKHM2	XP_016856246.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149913
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930