DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6051 and Zfyve1

DIOPT Version :9

Sequence 1:	NP_001097943.1	Gene:	CG6051 / 43271	FlyBaseID:	FBgn0039492	Length:	989	Species:	Drosophila melanogaster
Sequence 2:	NP_001346095.1	Gene:	Zfyve1 / 217695	MGIID:	3026685	Length:	777	Species:	Mus musculus

Alignment Length:	110	Identity:	37/110 - (33%)
Similarity:	55/110 - (50%)	Gaps:	6/110 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   862 TSSSSEQNSPVSAR--SGSRRRLQSNNETQM-PSSATSTSAT--LSPPAWIPDGKAPRCMACQTP 921
            |.:..:.|:..:.|  .|.....||.:|..: |:.|.::..|  ::|..|.|:.:...|..|.|.
Mouse   546 TDAFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQILSCNQCATS 610

  Fly   922 FTAFRRRHHCRNCGGVFCGVCSNASAPLPKYGLTKA-VRVCRDCY 965
            |.....:||||.||..||..||:.:.|:|:.|...| ||||..||
Mouse   611 FKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDSCY 655

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6051	NP_001097943.1	FYVE_LST2	902..966	CDD:277270	27/65 (42%)
Zfyve1	NP_001346095.1	Bbox1_ZFYVE1_rpt1	16..63	CDD:380877
		Bbox1_ZFYVE1_rpt2	69..121	CDD:380878
		GBP	174..410	CDD:206650
		Required for localization in the lipid droplets. /evidence=ECO:0000250\|UniProtKB:Q9HBF4	416..777		37/110 (34%)
		FYVE_like_SF	594..655	CDD:333710	24/60 (40%)
		FYVE_ZFYV1	711..771	CDD:277273
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839964
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840