Protein Alignment CG6051 and Zfyve26

DIOPT Version :9

• Sequence 1: NP_001097943.1
• Gene: CG6051 / 43271
• FlyBaseID: FBgn0039492
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: XP_017170500.1
• Gene: Zfyve26 / 211978
• MGIID: 1924767
• Length: 2546
• Species: Mus musculus
• Alignment Length: 1270
• Identity: 236/1270 - (18%)
• Similarity: 386/1270 - (30%)
• Gaps: 454/1270 - (35%)

  Fly    64 AITNLIMEEL--LGEDRDPRAFRAKFPEE----VLQENLAGQLWFGAECLAAG--------SSIM 114
            |..:|:.|:|  :...|.|.  ..|.||:    ..::.|..:|...::.|:..        |:..
Mouse   676 AFLSLLQEQLTEISSHRTPE--ETKLPEDQSCSAARDGLQSRLHRFSKVLSEAQWRYKVVTSNQG 738

  Fly   115 NRETESKEMRPLAQAVTKSLGNVRVLLR---DQCLKNNVPNSKTLHLDLNDSTTEQLYESLKIFD 176
            :.|..|:..||:|.. ..||...|...|   |...:.:.|:.:....:|:.||:|.
Mouse   739 SEEQPSRRYRPIATR-HSSLRRGRRTRRTRADGRERGSNPSLEGTSSELSTSTSEG--------- 793

  Fly   177 RLFAEFELSYVSAMVQVKSRHEYEMQQWIGVLFSETLQRALKIGLLDQEMVDAFDPGLMFS---- 237
                  .||.||..|:..||.:.:.|..|..:...|.:..|...:|.....:|....|||:
Mouse   794 ------SLSAVSGQVESDSRFQTQPQSSIIPMMFSTPESLLASCILRGNFAEAHQVVLMFNLKSS 852

  Fly   238 ---------------IPRLAIV----------------------------------AGLVVYAKG 253
                           |..||.|                                  ||:|.|:..
Mouse   853 PIAGELMFVERYQEVIQELARVEHKIENQNSDGGNNTIRRTGSGRSTLQAIGSAAAAGMVFYSIS 917

  Fly   254 PLNMDM------PGDQLSEMF----RPFRTILIKIRDLLRNLNNQELYQLEKLLC-------TNE 301
            .:...:      |...|.|.|    .|..| ...:|::|.:|:...:...:...|       ..:
Mouse   918 DVTEKLLSPSEDPIPTLQEDFWINATPMET-TTPLREVLEDLSPPAMAAFDLACCQCQLWKTCKQ 981

  Fly   302 DINTKVPLGSSSIEAP---------SPEHS--------------SHPTTSSSQNNNNSSNNNHSS 343
            .:.|.....|||:|:.         :|:..              |:|...:....:.:.......
Mouse   982 LLETAERRLSSSLESRGRRLDQVVLNPDGMRGFPFVLQQISKILSYPLMQTGLAKSETLEERGGG 1046

  Fly   344 SSTNTTST------TTTTAGTTNTHRTVERLVDQRNNNHNSNSNSSTNPTVEAATLRSPSMLSLS 402
            :..::.|.      .:.|.....:|.::.:.::|           :.....||..|.......||
Mouse  1047 APRSSISELLQMCWPSLTEDCVASHTSLSQQLEQ-----------ALQSLREALALPESKSTPLS 1100

  Fly   403 ATSTPTASPAPSPT--PSHSIASTSSAATSSTNPPADWSDGD--------------------DED 445
            ......|..||...  |.| |.|.....|.....||.....|                    ..|
Mouse  1101 CLVEQAAQKAPEAEAHPVH-IQSQLLQKTLGRQTPAGHRQTDYVGAFFSYCSSLAAVLLRSLSSD 1164

  Fly   446 EDDDDIDVDEEDI---ESSDDGTD----EEQLLKD------------------IVSADC------ 479
            .|..::.|....:   :||.....    |.|:..|                  |||..|
Mouse  1165 PDHVEVRVGNPFVLLQQSSSQLVSHLLLERQVPPDRLAALLAQEHLNLSVPQVIVSCCCEPLTLC 1229

  Fly   480 -------ASGYLIPNTNLGNLLQPQEVPLTDNFVAS-----EDDEYGTAEQQGHQGLEEDEPSTS 532
                   ||..|   |:||.|.:.....|.|....|     ...|..:||::.|...::..|:.:
Mouse  1230 LSRQSQQASSLL---THLGMLAREHASHLLDGLPLSTLGSPRPSENPSAERKSHSSPKDSLPAFT 1291

  Fly   533 AAMLAATRTLQRLRLPSSDNEPLAEPTTIKASE-EHMQQPSGRHRDSHSHRHHQRHHHHHHHRHP 596
            |:.||..::..::         ||....::.|. ..:.:|....::....|
Mouse  1292 ASALAFLKSRSKI---------LAMVACLRTSRGTKVSKPGLSWKELRGRR-------------- 1333

  Fly   597 HQHQHRQPHPHRTTRSGRKRCS--------LEAA-----DPERIQPDREQNLASGDTSAA----- 643
                    ....|.....:.|.        .|||     :|.:...:.:|:||:.....|
Mouse  1334 --------EAPLTAEKVAQECEHLLEQFPVFEAALLANWEPLQQASEPKQSLAASLCGQANLSTV 1390

  Fly   644 -----SSLS-------------------------------DDVSL-------------------- 652
                 |||:                               ||:|:
Mouse  1391 LLGLHSSLALDILTEAFEGALVARDWPRALQLIDVYGQDLDDLSIVQDSVLTCAAVCDKEGWQYL 1455

  Fly   653 ------AMRNTTARLKFKS---TENLLHRLFVCIAGVADQLQTNFASDLR--------------- 693
                  ::|:..| |:|..   .|:.|..|..|::.:|  :|....|:|:
Mouse  1456 FPVKDASLRSQLA-LRFVDKWPLESCLEILAYCVSDMA--VQEELKSELQRKLMELRVYQKILGL 1517

  Fly   694 ---------QILRSVFLMNMSTAQEEIDIPEKTKESELFE------------------------F 725
                     |.|||....:.|..   :|:...::|.||.|                        .
Mouse  1518 QDPPVWCDWQTLRSCCAEDPSAV---MDMMLDSQEYELCEEWGRLYPIPREHLVSLHHKHLLHLL 1579

  Fly   726 RASEND-----------------VIQESAGSNQSIYSAEEVNPELDNVFSAGGGNQATGQRHSAG 773
            ..||:|                 |.:.|...:.|:.::.    .|.|..::....:.|..||...
Mouse  1580 ERSEHDKALQLLQRIPDPTMCLEVTERSLDQHPSLATSH----FLANYLTSHFYGELTTDRHREI 1640

  Fly   774 ASMQRNNTIDLASQPGE---------GSP-------------SGATTATSRSH-VTRSRSLG--- 812
            .::...:.: |.:.|.:         .||             ..||||....| :...:.:|
Mouse  1641 QALYMGSKV-LLTLPEQHRASYARLSSSPLLMLEQLLMNMKVDWATTAVQTLHQLLAGQDIGFTL 1704

  Fly   813 DQ------EAASSATSSTAQLRQLEQQQQQQQLQIQLQRQRNNSVGSNTPSSASSTSSSSEQNSP 871
            |:      ..|..|......||    :::.....|.||...:.:..|.|.|.:||...|:.. :|
Mouse  1705 DEVDSLLSRYAGKALDLPYPLR----EKRSADSMIHLQEPVHQASDSETLSRSSSAEFSAAA-AP 1764

  Fly   872 VSA--RSGSRRRLQSNNETQMPSSATSTSATLSPPA---WIPDGKAPRCM-ACQTPFTAFRRRHH 930
            .||  ||.|.:. ::..:||.|.......   :|||   |:||.....|| .|:..||.|.||||
Mouse  1765 GSALVRSPSPKE-RAFPQTQPPVEFVPPE---TPPARDQWVPDETESVCMVCCREHFTMFNRRHH 1825

  Fly   931 CRNCGGVFCGVCSNASAPLPKYGLTKAVRVCRDCY 965
            ||.||.:.||.||.....:..: .....|||..||
Mouse  1826 CRRCGRLVCGSCSTKKMVVEGF-RENPTRVCDQCY 1859

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6051	NP_001097943.1	FYVE_LST2	902..966	CDD:277270	29/68 (43%)
Zfyve26	XP_017170500.1	FYVE_ZFY26	1800..1860	CDD:277263	26/61 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839962
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930