Protein Alignment CG6059 and cfap58

DIOPT Version :10

• Sequence 1: NP_651541.2
• Gene: CG6059 / 43270
• FlyBaseID: FBgn0039491
• Length: 884
• Species: Drosophila melanogaster
• Sequence 2: NP_001119542.1
• Gene: cfap58 / 779580
• XenbaseID: XB-GENE-5719803
• Length: 871
• Species: Xenopus tropicalis
• Alignment Length: 929
• Identity: 238/929 - (25%)
• Similarity: 417/929 - (44%)
• Gaps: 198/929 - (21%)

  Fly    47 NDKFFSSSYQLVQSLSERFPFLAGKVKL------YVDILSRLHAHYVNE---VEQGRAMHEKVRT 102
            ::|.|.:   |.:...|....|||...|      |..:.|.|...|.||   :.:.|.::.::..
 Frog    12 DEKAFEA---LERDFQEVLQELAGDKSLEKFQIEYEKLHSALKKSYDNEKRLMAKCRELNAEIVA 73

  Fly   103 ADEKLQLALRTTAISEAMMEHLRESLEDAWRNEDATKNREETMQLQLMSL---VRSDQSNMTKGT 164
            ...|:..|::.:...::.:..|::.:|.||:..||...:|:..:..:.||   |:|....:.:|.
 Frog    74 NAAKVATAIKLSQEDQSTISSLKKEIEKAWKMVDAAYEKEQRAKETVNSLKDEVKSLSKLVEQGA 138

  Fly   165 TDHVPISNKDLQLHRLVL-RERDRLAAE--------LKDHQKRLQTNRLYSESVEVMIEVYKEII 220
            .......:.||...:..| :|||.|.||        :|..:.:.:..:...|:.:.:|:..:||.
 Frog   139 GMSAGQEHSDLLSAKEELSKERDELLAEVVKLRENLVKATELQQEAEKSKEEAEQGIIQFQQEIQ 203

  Fly   221 SKLN----------------------ARAKKAELDNFR------LEHRCNVEQDKYEDRLLH--L 255
            .:.|                      |.||:.|:.:.:      .|....:||...|:::|:  :
 Frog   204 MRQNEASRESRKKEKLEKDLRGLQSEAEAKQLEIKSMQQNLTRNKEELQRLEQQLKENKILNERV 268

  Fly   256 NKELVAVVQQNEELQAAEKDFMELAATNEALKQRSDRLSRENHTLTKSLRIMEDEKNKLQTSL-K 319
            :|||..|..:|.:||          ..||.....:|:|::||......|:..|||.|:::..: |
 Frog   269 SKELEQVQMRNNKLQ----------QENEQQSVLNDQLTQENQQKQLELKAKEDEVNQMRQEISK 323

  Fly   320 VSEGLNDAQR---------------RDKL---------DLELARRSAERDAKKKADDSMILERRF 360
            :|:.....||               |:.|         :||.|::.||.|  |||.:.::.||..
 Frog   324 ISKARETIQRKYRQMEEQKIEVEQQRETLKNQITGFERELESAKKQAEID--KKAVEELVRERDM 386

  Fly   361 ---HLLAKKNTELNDQVLVNQNELKVQEKKMLMATAKLNEAIRQKEEIARSRDKLRAEISRLNDI 422
               :||...|.....|.||..:|   |.||      .|.|.|:..:|.|:.:.|:..::.:..|
 Frog   387 LNKNLLRAANATDKQQSLVKLHE---QSKK------NLEEEIQSYKEEAQKQRKIIYQLEKERD- 441

  Fly   423 VAGVRHEIASIRHQMQDLLTDLLRANKQLDEKDLQV----QKIA----REKREQSLELNDAYKKI 479
                     ...::..||...:|:..:.:..:::|:    :|||    :.|::|:|     |:
 Frog   442 ---------RYINEASDLTQKVLQHMEDIKVREMQIFDYKKKIAEAETKLKQQQNL-----YE-- 490

  Fly   480 DGIEETLALKSERLEVLQVELQQKQQEFANVKKQMEVIQSEKVMLMKTMDMCSRDRSTLQNTMTK 544
                   |::|:| .:....|.:.|.|...:|::::::..:       :|....:.|:.::.:.|
 Frog   491 -------AVRSDR-NLYSKNLIEAQDEITEMKRKLKIMNHQ-------VDQLKEEISSKESVLVK 540

  Fly   545 --LTHQINQMTSSLAINEKEISSLKNQIEQLNRTVKQKQNEIHAKSRLLASTKTDLREMKIRLEQ 607
              |.||         ..|||..:||.:::      |.||..:..| :|:.:.:.:.:::...:.:
 Frog   541 VHLEHQ---------RIEKEKEALKAELQ------KMKQQSVETK-QLIDNQEAEEKKLLKIISE 589

  Fly   608 AAHTIDTDEKRFKNMACALDEVTKEKSLVGLQMVRRNDEVRLLREKLDMMQKAIDRGTMQYNQRV 672
            |    |.:..|.|.   .|::|..|:.::|.|:||||||:.||.||:.:.|..:::|.:||.|||
 Frog   590 A----DAERLRQKK---ELEQVISERDILGSQLVRRNDELALLYEKIKIQQSILNKGEIQYKQRV 647

  Fly   673 EDIRLLKLEVVNLRTSHECMQREVGNKAAMRHDVIRLERQLNQERLKVSAYSEELSRPCRIHRWR 737
            |||||||||:..||.....:.:.|.|...:|.:|..::|.|.:||.:..|..|||..|..:||||
 Frog   648 EDIRLLKLEIKKLRREKGILTKTVANVEELRREVYHMQRDLLKERTRCRALEEELENPMNVHRWR 712

  Fly   738 VLLGKDPRRFELIRKIQQLLKRNIRLSVERENKAKELAELEHVHEEFKRQMTNLPDPSVRQKLCI 802
            .|...||..:|||:||..|.||.||.:.|...|...|.|.|.::.|.|..:...|.|...::|.:
 Frog   713 KLEASDPSTYELIQKIHTLQKRLIRKTEEVVEKELLLQEKEKLYVELKHILARQPGPEAAEQLQV 777

  Fly   803 QQRINRRQTRQLKAMKAELRI----------------NEIDLKTREHLIEGFQEQ---------- 841
            .|:..|.:|:||||:.|||.:                ||:....:::|.:..:||
 Frog   778 YQKTLRDKTKQLKALSAELNMYESQNQEHKYEIERLANELQNMKKKYLTQKRREQQAREKERGVA 842

  Fly   842 ---LRLHHLENKENFIGKG 857
               |:..|||. ..|.|.|
 Frog   843 DTFLQQQHLEG-PRFTGGG 860

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6059	NP_651541.2	Smc	<251..>524	CDD:440809	71/310 (23%)
		SMC_prok_B	<425..715	CDD:274008	77/299 (26%)
cfap58	NP_001119542.1	PTZ00121	<2..427	CDD:173412	102/438 (23%)
		Smc	229..>838	CDD:440809	187/684 (27%)