Protein Alignment CG5882 and CFAP58

DIOPT Version :9

• Sequence 1: NP_651540.1
• Gene: CG5882 / 43269
• FlyBaseID: FBgn0039490
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_001008723.1
• Gene: CFAP58 / 159686
• HGNCID: 26676
• Length: 872
• Species: Homo sapiens
• Alignment Length: 862
• Identity: 215/862 - (24%)
• Similarity: 420/862 - (48%)
• Gaps: 91/862 - (10%)

  Fly    46 DNVQRLLICGSRYKSDLRLEKERSQELRKEIESLEERLENAARVTKLDMATIEELRGVIEGAWKQ 110
            ||.:||:              .:.:||..||.....::..|.::::.|..||..|:..||.|||.
Human    55 DNEKRLM--------------AKCRELNAEIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKM 105

  Fly   111 KDAAQIREQSAQDEVLSLREKLDESEQMV---------AHLNEKRLAMSKRDDGKERERLNAEIA 166
            .|:|..:||.|::.:|:|:|::....::|         .|.|.:.|...|.:..|||::|.:|:.
Human   106 VDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVV 170

  Fly   167 DLNKRLHLQRTYATELDHTIEGLEAKNKELLKLLDETSSDACNLKRKSDALTKELSTM------- 224
            .|.:.|........|.:.:.|..|....:..:.:.:..::|....||.:.|.|||..:
Human   171 KLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSR 235

  Fly   225 --------------KTEESRYQEQISQMKSANEHLTKVKVRQNLQILSLKTNLEHLNTQHNAANN 275
                          |.|..:.::|:.:.|..||.  ..|..:..|:.:.|  |:..|.||:....
Human   236 QTEIKALQQYVQKSKEELQKLEQQLKEQKILNER--AAKELEQFQMRNAK--LQQENEQHSLVCE 296

  Fly   276 KLAKITVDLEYTVQERDKNKRALNQRINLLKVREDELIKVRQDNGKLAKSQEAIARKYAVLDEAK 340
            :|:            ::..::||.     ||.:|:|:.::|.|.|||.|.:|.|.:|....::.|
Human   297 QLS------------QENQQKALE-----LKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQK 344

  Fly   341 REVETLNIRLRTQLGTQDKELESMRRVVHHFEKNNENLTKERDSLRRE-LQAEHHQLEQSN--AQ 402
            .|||.....|:.|:...::|:|:.::......|..:.|.:|||.|.:. |:|.:...:|::  ..
Human   345 AEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKL 409

  Fly   403 HQEAQHEVRALKDTITTMDTKLKKLNEDANKLKKEKTKKLDEIQHWIDKLDALQNEMHLKENYEI 467
            |::|:   |.|:..|.....:.:|..:....|:||:.:.:::......|:.....::.::|....
Human   410 HEQAK---RNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRETQIF 471

  Fly   468 ELKRTISDLEAKCSKFQQQHDGLAAERQTLQRSVQLADEERQKLRDQLVNLQAHVEKLKAKIGYR 532
            :.::.|::.|.|..:.|..::.:.::|....:::..|.:|...::.:|..:...|::||..|..:
Human   472 DYRKKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAK 536

  Fly   533 DGEISRLQLQIDRMEKERRLLRNEIRHAQLGQQHTKAELLDKRKENDRH-AKSLQEDEQKLARLR 596
            :..:.:|.|:..|:|||:..|:.|::..:.....|| ..::|::..:|. .:.:.|.:.:..|.:
Human   537 ESALVKLHLEQQRIEKEKETLKAELQKLRQQALETK-HFIEKQEAEERKLLRIIAEADGERLRQK 600

  Fly   597 KDVDNLMNEKNAISAALTKRNEEFDRLKHSQENLQTVYDQTQRQCSQYQDDMRLMGVEIKNLRTE 661
            |::|.:::|::.:.:.|.:||:|...|....:..|:|.::.:.|.:|..:|||::.:|||.||.|
Human   601 KELDQVISERDILGSQLVRRNDELALLYEKIKIQQSVLNKGESQYNQRLEDMRILRLEIKKLRRE 665

  Fly   662 RDVLRADRESAADLRQELLQMHRMLNQERIKARALQDEMVTPMNVHRWRLLSGKDPEKMDLLGRI 726
            :.:|.....:..:||||...|.|.|.:||.:.|||::|:..|:||||||.|...||...:|:.:|
Human   666 KGILARSMANVEELRQEFFHMQRELLKERTRCRALEEELENPLNVHRWRKLEASDPNAYELIQKI 730

  Fly   727 SILRKQLLQQNVAASEQERALNEAQQLYAALREFMLKLPSHKVRAELNSVKANLSAKDRKLKVLK 791
            ..|:|:|:.:.....|:|..|.|.::||..|:..:.:.|..:...:|...:..|..|.::||||.
Human   731 HTLQKRLISKTEEVVEKELLLQEKEKLYMELKHVLARQPGPEAAEQLKLYRRTLHDKKQQLKVLS 795

  Fly   792 AELSAREADEKSKKEKLEEMRVSLALTKTQLLEEKKHKQKLLEERQLLEQMHCYSAPAQL----- 851
            :||:..|...|..|.::|::...|...|.:.|.:|: |::|.:.:.        :||...
Human   796 SELNMYEVQSKEYKYEVEKLTNELQNLKKKYLAQKR-KEQLQKNKD--------TAPMDNTFLMV 851

  Fly   852 ----PRTLGAGFKMVSS 864
                |...|.||.:.|:
Human   852 KPNGPGFTGGGFPLRST 868

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5882	NP_651540.1	Smc	61..>699	CDD:224117	161/671 (24%)
CFAP58	NP_001008723.1	Smc	<33..>709	CDD:224117	167/692 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141971
Domainoid	1	1.000	285	1.000	Domainoid score	I1631
eggNOG	1	0.900	-	-		E1_28HHA
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H77312
Inparanoid	1	1.050	285	1.000	Inparanoid score	I2862
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1077673at2759
OrthoFinder	1	1.000	-	-		FOG0006172
OrthoInspector	1	1.000	-	-		oto90202
orthoMCL	1	0.900	-	-		OOG6_103263
Panther	1	1.100	-	-	LDO	PTHR32083
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5074
SonicParanoid	1	1.000	-	-		X4455
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.830