Protein Alignment CG5880 and ZDHHC12

DIOPT Version :9

• Sequence 1: NP_651539.3
• Gene: CG5880 / 43268
• FlyBaseID: FBgn0039489
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: NP_001304944.2
• Gene: ZDHHC12 / 84885
• HGNCID: 19159
• Length: 322
• Species: Homo sapiens
• Alignment Length: 403
• Identity: 92/403 - (22%)
• Similarity: 140/403 - (34%)
• Gaps: 138/403 - (34%)

  Fly     2 TRITW----------RGHSTQELLSILRLRWSYMKHCW--HSLTF---NAHMNSSYASDVCLTPI 51
            |.:||          ...|..|||:.       ..|.|  |...|   ..|..:|..:....||:
Human    18 TVLTWGITLVLFLHDTDKSADELLAT-------HSHSWNQHLQAFAQPGTHFPTSNCTPTPPTPV 75

  Fly    52 FWFVDNYTHCLGPFFVVGVAALTTSVVSIAYWIGLPFWWAKSQL---VTYFLLIVGNWLLLNVVF 113
                           :.|.|:|.:....     .|..|..:.:|   :|:.||::|:.||
Human    76 ---------------LPGPASLCSPASP-----ELRQWEEQGELLLPLTFLLLVLGSLLL----- 115

  Fly   114 HYVMAVITPAGH-----PPEGVSLVEAVSM---------CGKCIAPKPPRTHHCSICNRCILKMD 164
             |:...:...|:     .|:.....|..:|         |..|:..:|.|..||..|.||:.:.|
Human   116 -YLAVSLMDPGYVNVQPQPQEELKEEQTAMVPPAIPLRRCRYCLVLQPLRARHCRECRRCVRRYD 179

  Fly   165 HHCPWLNNCVGYGNHRYFFLYMTYTTLGCLFLILFGLEIGHKYL-W--LDHGENWTEIEPLEGQP 226
            |||||:.||||..||..|.:|:...    |.::|:||     || |  |...:.|       ||.
Human   180 HHCPWMENCVGERNHPLFVVYLALQ----LVVLLWGL-----YLAWSGLRFFQPW-------GQW 228

  Fly   227 VKFNLSGHIIPVTHPNEYDEFVLPPAVHNLPTPIVDTDAASPGRRRALWFMAFTNVAVVLALGS- 290
            :                                          |...|.|..|..:::...:.|
Human   229 L------------------------------------------RSSGLLFATFLLLSLFSLVASL 251

  Fly   291 LSIWHAKLITRGETSVEAHINEAERKRHLQQQRIYINPYNFGTKKNW-KLFLGLVRGRSFWRTVL 354
            |.:.|..|:....|:.|  ...:.|..:|:|:.  .||::.|..:|. ..|.|...|.  |.|:
Human   252 LLVSHLYLVASNTTTWE--FISSHRIAYLRQRP--SNPFDRGLTRNLAHFFCGWPSGS--WETL- 309

  Fly   355 LPSWHKPEGTGLS 367
               |.:.|..|.|
Human   310 ---WAEEEEEGSS 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5880	NP_651539.3	zf-DHHC	139..>201	CDD:279823	25/61 (41%)
ZDHHC12	NP_001304944.2	DHHC	<178..272	CDD:388695	35/153 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900