DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5880 and Zdhhc16

DIOPT Version :9

Sequence 1:	NP_651539.3	Gene:	CG5880 / 43268	FlyBaseID:	FBgn0039489	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_001347605.1	Gene:	Zdhhc16 / 74168	MGIID:	1921418	Length:	377	Species:	Mus musculus

Alignment Length:	372	Identity:	158/372 - (42%)
Similarity:	207/372 - (55%)	Gaps:	48/372 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LLSILRLRWSYMKHCWHSLTFNAHMNSSYASDVCLTPIFWFVDNYTHCLGPFFVVGVAALTTSVV 78
            ||..|..||.|.|.|..||.:|:...|..|.|....|::|.|||.....|..|||.|..||.|:|
Mouse    31 LLRGLVQRWRYGKVCLRSLLYNSFGGSDTAVDAAFEPVYWLVDNVIRWFGVVFVVLVIVLTGSIV 95

  Fly    79 SIAYWIGLPF---WWAKSQLVTYFLLIVGNWLLLNVVFHYVMAVITPAGHPPEGVSLVEAVSMCG 140
            :|||...||.   .::..:|..:|  ...:|.|:.:||||..|:.||.|:||:|.:.:..||:|.
Mouse    96 AIAYLCVLPLILRTYSVPRLCWHF--FYSHWNLILIVFHYYQAITTPPGYPPQGRNDIATVSICK 158

  Fly   141 KCIAPKPPRTHHCSICNRCILKMDHHCPWLNNCVGYGNHRYFFLYMTYTTLGCLFLILFGLEIGH 205
            |||.|||.|||||||||||:|||||||||||||||:.||||||.:..:.||||:: ..:|
Mouse   159 KCIYPKPARTHHCSICNRCVLKMDHHCPWLNNCVGHYNHRYFFSFCFFMTLGCVY-CSYG----- 217

  Fly   206 KYLWLDHGENWTEIEPLEGQPVKFNLSGHIIPVTHPNEYDEFVLPPAVHNLPTPIVDTDAASPGR 270
              .|....|.:..||.:: |..|..|              :.:.....|..|.|....      |
Mouse   218 --SWDLFREAYAAIEKMK-QLDKNKL--------------QAIANQTYHQTPPPTFSF------R 259

  Fly   271 RRA-------LWFMAFTNVAVVLALGSLSIWHAKLITRGETSVEAHINEAERKRHLQQQRIYINP 328
            .|.       |||:.   .:|.||||:|::|||.||:|||||:|.|||:.||:|...:.|::.||
Mouse   260 ERITHKSLVYLWFLC---SSVALALGALTMWHAVLISRGETSIERHINKKERRRLQAKGRVFRNP 321

  Fly   329 YNFGTKKNWKLFLGLVRGRSFWRTVLLPSWHKPEGTGLSFHTVNDAP 375
            ||:|...|||:|||:..||.:...|||||.|.|.|.|:|:    |.|
Mouse   322 YNYGCLDNWKVFLGVDTGRHWLTRVLLPSSHLPHGNGMSW----DPP 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5880	NP_651539.3	zf-DHHC	139..>201	CDD:279823	43/61 (70%)
Zdhhc16	NP_001347605.1	DHHC	156..305	CDD:396215	78/180 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842489
Domainoid	1	1.000	132	1.000	Domainoid score	I5100
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11377
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2986
Isobase	1	0.950	-	0	Normalized mean entropy	S2852
OMA	1	1.010	-	-		QHG55511
OrthoDB	1	1.010	-	-		D1491968at2759
OrthoFinder	1	1.000	-	-		FOG0005702
OrthoInspector	1	1.000	-	-		oto92559
orthoMCL	1	0.900	-	-		OOG6_103703
Panther	1	1.100	-	-	LDO	PTHR12246
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5343
SonicParanoid	1	1.000	-	-		X4100
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750