DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5880 and Zdhhc4

DIOPT Version :9

Sequence 1:	NP_651539.3	Gene:	CG5880 / 43268	FlyBaseID:	FBgn0039489	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_082655.1	Gene:	Zdhhc4 / 72881	MGIID:	1920131	Length:	343	Species:	Mus musculus

Alignment Length:	168	Identity:	49/168 - (29%)
Similarity:	68/168 - (40%)	Gaps:	42/168 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 HCLGPFFVVGVAALTTSVVSIAYW-----------IGLPFWWAKSQLVTYFLLIVGNWLLLNVVF 113
            |...|.|:| :..|...:|...|.           ..||:     .|:.|.||.|      |:||
Mouse    62 HTRHPTFIV-LHLLLQGLVYAEYTCEVFGYCRELEFSLPY-----LLLPYVLLSV------NLVF 114

  Fly   114 HYVMAVITPAGHPPEGVSLVEAV-----------SMCGKCIAPKPPRTHHCSICNRCILKMDHHC 167
            ..:.....|........|.:..|           |.|..|...||.|:.||.:|:||:.:.||||
Mouse   115 FTLTCAANPGTITKANESFLLQVYKFDDVMFPKNSRCPTCDLRKPARSKHCRLCDRCVHRFDHHC 179

  Fly   168 PWLNNCVGYGNHRYFFLYM--------TYTTLGCLFLI 197
            .|:|||:|..|.|||.:|:        |..|:...||:
Mouse   180 VWVNNCIGAWNTRYFLIYLLTLTASAATIATVTAAFLL 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5880	NP_651539.3	zf-DHHC	139..>201	CDD:279823	28/67 (42%)
Zdhhc4	NP_082655.1	DHHC	151..292	CDD:396215	28/67 (42%)
Zdhhc4	NP_082655.1	Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q9NPG8	340..343
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810