DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5880 and zdhhc4

DIOPT Version :9

Sequence 1:	NP_651539.3	Gene:	CG5880 / 43268	FlyBaseID:	FBgn0039489	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_956343.2	Gene:	zdhhc4 / 561817	ZFINID:	ZDB-GENE-030131-9031	Length:	345	Species:	Danio rerio

Alignment Length:	235	Identity:	62/235 - (26%)
Similarity:	87/235 - (37%)	Gaps:	75/235 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 CGKCIAPKPPRTHHCSICNRCILKMDHHCPWLNNCVGYGNHRYFFLYM-----------TYTTLG 192
            |..|...||.|:.||.:||||:.:.||||.|:|||:|..|.|||.||:           ..||..
Zfish   153 CSTCQLIKPARSKHCRVCNRCVQRFDHHCVWVNNCIGAQNTRYFMLYLLSVCAMAGNIAVLTTDM 217

  Fly   193 CLFLIL-FGLEIGHKYLWLDHGENWTEIEPLEG--QPVKFNLSGHIIPVTHPNEYDEFVLPPAVH 254
            .|..:| .||...|   ::|.          :|  ||     :|.:..:.|     .|:..|
Zfish   218 LLQTVLRTGLLHAH---YIDE----------QGIQQP-----AGPLFIIQH-----LFLTFP--- 256

  Fly   255 NLPTPIVDTDAASPGRRRALWFMAFTNVAVVLALGSLSIWHAKLITRGETSVEAHINEAERKRHL 319
                             |.::.:.|. |.|...|....::|..|:...:||.|....:....:|.
Zfish   257 -----------------RIVFMLGFL-VFVFFLLAGYCLFHFYLVLVNQTSNEWFKAKGHNCQHC 303

  Fly   320 QQQ-----RIYINP----YNFGTKKNWKLFLGLVRGRSFW 350
            ...     |...||    |:.|..||        .|..||
Zfish   304 HPYSGHNCRTSYNPFRGFYHRGILKN--------IGEIFW 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5880	NP_651539.3	zf-DHHC	139..>201	CDD:279823	30/73 (41%)
zdhhc4	NP_956343.2	DHHC	152..296	CDD:396215	51/186 (27%)
zdhhc4	NP_956343.2	Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q9NPG8	342..345
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910