DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5880 and ZDHHC4

DIOPT Version :9

Sequence 1:	NP_651539.3	Gene:	CG5880 / 43268	FlyBaseID:	FBgn0039489	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_001358221.1	Gene:	ZDHHC4 / 55146	HGNCID:	18471	Length:	359	Species:	Homo sapiens

Alignment Length:	231	Identity:	58/231 - (25%)
Similarity:	88/231 - (38%)	Gaps:	89/231 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 QLVTYFLLIVGNWLLLNV-VFHYVM------AVITPAGHP-------------PEGVSLVEAVSM 138
            :|..::||:  .:|||.| :|.:.:      .:||.|...             |:.|       .
Human    95 ELSLHYLLL--PYLLLGVNLFFFTLTCGTNPGIITKANELLFLHVYEFDEVMFPKNV-------R 150

  Fly   139 CGKCIAPKPPRTHHCS---------------ICNRCILKMDHHCPWLNNCVGYGNHRYFFLYM-- 186
            |..|...||.|:.|||               :||.|:.:.||||.|:|||:|..|.|||.:|:
Human   151 CSTCDLRKPARSKHCSECGSRDSSGTSNSTCVCNWCVHRFDHHCVWVNNCIGAWNIRYFLIYVLT 215

  Fly   187 ------TYTTLGCLFLILFGL-----------EIGH----------KYLWLDHGENWTEIEPLEG 224
                  |...:...||:...:           ::||          :||:|    .:..|..:.|
Human   216 LTASAATVAIVSTTFLVHLVVMSDLYQETYIDDLGHLHVMDTVFLIQYLFL----TFPRIVFMLG 276

  Fly   225 QPV--KFNLSGHIIPVTHPNEYDEFVLPPAVHNLPT 258
            ..|  .|.|.|:::          |||..|..|..|
Human   277 FVVVLSFLLGGYLL----------FVLYLAATNQTT 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5880	NP_651539.3	zf-DHHC	139..>201	CDD:279823	28/84 (33%)
ZDHHC4	NP_001358221.1	DHHC	151..307	CDD:366691	45/166 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910